TermGenie is a web application for ontology content generation. It generates new terms according to pre-defined templates, and uses OWL reasoners to place the term in the correct place in the ontology

Originally this was devolped for the GeneOntology, but TermGenie uses a generic approach applicable to many ontologies.

TermGenie – a web-application for pattern-based ontology class generation
Heiko Dietze, Tanya Z. Berardini, Rebecca E. Foulger, David P. Hill, Jane Lomax, David Osumi-Sutherland, Paola Roncaglia, and Christopher J. Mungall
Journal of Biomedical Semantics 2014, 5:48 doi:10.1186/2041-1480-5-48 Published: 11 December 2014

Link to JBMS open access article