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Apollo is a browser-based tool for visualization and editing of sequence annotations. It is designed for distributed community annotation efforts, where numerous people may be working on the same sequences in geographically different locations; real-time updating keeps all users in sync during the editing process.

Apollo was originally developed as a collaboration between the Berkeley Drosophila Genome Project (part of the FlyBase consortium) and The Sanger Institute in Cambridge, UK. It was used by the FlyBase biologists to construct the Release 3 and 4 annotations on the finished Drosophila melanogaster genome, and has also been a primary vehicle for sharing these annotations with the community. Apollo allows researchers to explore genomic annotations at many levels of detail, and to perform expert annotation curation, all in a graphical environment.


  • Dunn NA, Unni DR, Diesh C, Munoz-Torres M, Harris NL, Yao E, Rasche H, Holmes IH, Elsik CG, Lewis SE (2019). Apollo: Democratizing genome annotation. PLoS Comput Biol. Feb 6;15(2):e1006790. PMCID: PMC6380598
  • Lee E, Helt GA, Reese JT, Munoz-Torres MC, Childers CP, Buels RM, Stein L, Holmes IH, Elsik CG, Lewis SE (2013). Web Apollo: a web-based genomic annotation editing platform. Genome Biol, 2013 Aug 30;14(8):R93. PMCID: PMC4053811
  • Lee E, Harris N, Gibson M, Chetty R, Lewis S (2009). Apollo: a community resource for genome annotation editing. Bioinformatics. Oxford University Press; 2009;25(14):1836–1837.
  • Lewis SE, Searle SMJ, Harris N, Gibson M, Iyer V, Richter J, Wiel C, Bayraktaroglu L, Birney E, Crosby MA, Others (2002). Apollo: a sequence annotation editor. Genome Biol. BioMed Central; 2002;3(12):research0082–1.