2011-06-03 24:08:2011 09:07 tmeehan uberon $Revision: 1.52 $ See PMID:15693950, PMID:12799354, PMID:20123131, Contact Alexander Diehl, addiehl@buffalo.edu, University of Buffalo. Terms in this subset group together terms from different anatomy ontologies that have conflicting upper ontology/CARO assignments. For example, in FMA the naris is immaterial and in ZFA it is an organism subdivision. classes that have some inconsistency with FMA core classes typically found across metazoa. one purpose is to create a rough set of terms that could be used to start a new metazoan AO. Note this subset is not yet fully fleshed out Fission yeast GO slim PIR GO slim classes that are defined by relative position counting from first in a series in an individual organism rather than by homology Abnormal/normal slim A class which has a weakened disjointness axiom, to avoid inconsistency. These are kept separately in the uberon_disjoint_from_strict ontology. functional_classification Candida GO slim Subset consisting of classes creating for grouping purposes Indicates that subclasses in AOs may be inappropriately linked Scalar slim core classes typically found across vertebrates. one purpose is to create a rough set of terms that could be used to start a new vertebrate AO A grouping class that originates in two or more separate anatomical ontologies. Includes 'region of X' type terms derived from the union of EHDAA2 and EMAPA - still to be checked abstract upper-level terms not directly useful for analysis Prokaryotic GO subset somewhat fuzzy grouping for analysis purposes, currently composed of something like: liver, heart, skeletal, kidney, bladder, brain, skin, mouth, esophagus, stomach, small intestine, large intestines, trachea nose, lungs, brain, spinal cord, peripheral nerves, kidneys, ureters, bladder, urethra, gonads Yeast GO slim Value slim unvetted Plant GO slim GOA and proteome slim Uberon slim Generic GO slim A class that represents an early developmental structure, like a blastocyst. This part of the ontology is undergoing review to remove inappropriate grouping classes. Relational slim: types of quality that require an additional entity in order to exist cell_quality Attribute slim Absent/present slim Disposition slim High-level terms not to be used for direct annotation developmental_classification uberon This is an OWL translation of an ontology whose native representational form is .obo. The translation was performed using the oboInOwl xslt library. For details, see http://www.berkeleybop.org/obo-conv.cgi cell Anatomical structure that has as its parts a maximally connected cell compartment surrounded by a plasma membrane. CARO:mah http://purl.org/obo/owl/CARO#CARO_mah cell KUPO:0000002 http://purl.org/obo/owl/KUPO#KUPO_0000002 GO:0005623 http://purl.org/obo/owl/GO#GO_0005623 FMA:68646 http://purl.org/obo/owl/FMA#FMA_68646 primary cell line cell cell BTO:0002290 http://purl.org/obo/owl/BTO#BTO_0002290 permanent cell line cell cell cell in vivo cell cell by organism A classification of cells by the organisms within which they are contained. FB:ma http://purl.org/obo/owl/FB#FB_ma cell fibroblast neural crest derived cell neuronal receptor cell (sensu Animalia) cell early embryonic cell A cell found in the embryo before the formation of all the gem layers is complete. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm cell cranial neural crest cell cell fusiform initial replaced_by: PO:0000079 Obsolete. Use PO:0000079 from Plant Ontology instead. An elongated cell with approximately wedge-shaped ends, found in the vascular cambium, which gives rise to the elements of the axial system in the secondary vascular tissues. ISBN:0471245208 http://purl.org/obo/owl/ISBN#ISBN_0471245208 xylem mother cell xylem initial cell CL:0000274 cell line cell cell trunk neural crest cell cell cell by class cell dentine secreting cell cell germ line stem cell germline stem cell cell male germ cell cell FMA:72290 http://purl.org/obo/owl/FMA#FMA_72290 male germ line stem cell cell spermatocyte A male germ cell that develops from spermatogonia. The euploid primary spermatocytes undergo meiosis and give rise to the haploid secondary spermatocytes which in turn give rise to spermatids. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm MESH:A.05.360.490.890.880 http://purl.org/obo/owl/MESH#MESH_A.05.360.490.890.880 cell BTO:0001275 http://purl.org/obo/owl/BTO#BTO_0001275 FMA:84049 http://purl.org/obo/owl/FMA#FMA_84049 FBbt:00004936 http://purl.org/obo/owl/FBbt#FBbt_00004936 spermatid A male germ cell that develops from the haploid secondary spermatocytes. Without further division, spermatids undergo structural changes and give rise to spermatozoa. MESH:A.05.360.490.890.860 http://purl.org/obo/owl/MESH#MESH_A.05.360.490.890.860 Nematoblast cell FMA:72294 http://purl.org/obo/owl/FMA#FMA_72294 FBbt:00004942 http://purl.org/obo/owl/FBbt#FBbt_00004942 BTO:0001274 http://purl.org/obo/owl/BTO#BTO_0001274 sperm A mature male germ cell that develops from a spermatid. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm MESH:A.05.360.490.890 http://purl.org/obo/owl/MESH#MESH_A.05.360.490.890 spermatozoid sperm cell spermatozoon cell FBbt:00004954 http://purl.org/obo/owl/FBbt#FBbt_00004954 BTO:0001277 http://purl.org/obo/owl/BTO#BTO_0001277 FMA:67338 http://purl.org/obo/owl/FMA#FMA_67338 BTO:0002046 http://purl.org/obo/owl/BTO#BTO_0002046 spermatogonium An euploid male germ cell of an early stage of spermatogenesis. MESH:A.05.360.490.890.900 http://purl.org/obo/owl/MESH#MESH_A.05.360.490.890.900 cell FMA:72291 http://purl.org/obo/owl/FMA#FMA_72291 BTO:0000958 http://purl.org/obo/owl/BTO#BTO_0000958 FBbt:00004935 http://purl.org/obo/owl/FBbt#FBbt_00004935 female germ cell Female germ cell is a germ cell that supports female gamete production. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm PMID:11023867 http://purl.org/obo/owl/PMID#PMID_11023867 PMID:20454446 http://purl.org/obo/owl/PMID#PMID_20454446 cell female germ line stem cell cell oocyte A female germ cell that has entered meiosis. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0721662544 http://purl.org/obo/owl/ISBN#ISBN_0721662544 cell BTO:0000964 http://purl.org/obo/owl/BTO#BTO_0000964 FMA:18644 http://purl.org/obo/owl/FMA#FMA_18644 FBbt:00004886 http://purl.org/obo/owl/FBbt#FBbt_00004886 oogonial cell An undifferentiated germ cell that proliferates rapidly and gives rise to oocytes. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0721662544 http://purl.org/obo/owl/ISBN#ISBN_0721662544 cell FMA:83673 http://purl.org/obo/owl/FMA#FMA_83673 egg A female gamete where meiosis has progressed to metaphase II and is able to participate in fertilization. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0721662544 http://purl.org/obo/owl/ISBN#ISBN_0721662544 ovum mature oocyte cell BTO:0003801 http://purl.org/obo/owl/BTO#BTO_0003801 FBbt:00000034 http://purl.org/obo/owl/FBbt#FBbt_00000034 BTO:0000369 http://purl.org/obo/owl/BTO#BTO_0000369 FMA:67343 http://purl.org/obo/owl/FMA#FMA_67343 invertebrate nurse cell A germline cell that contributes to the development of the oocyte by transferring cytoplasm directly to oocyte. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm PMID:15848391 http://purl.org/obo/owl/PMID#PMID_15848391 nurse cell cell FBbt:00004878 http://purl.org/obo/owl/FBbt#FBbt_00004878 BTO:0000953 http://purl.org/obo/owl/BTO#BTO_0000953 smooth muscle cell neural crest derived cell CNS neuron (sensu Nematoda and Protostomia) cell neuron neural crest derived cell glioblast cell FBbt:00005145 http://purl.org/obo/owl/FBbt#FBbt_00005145 neuroblast cell FBbt:00005146 http://purl.org/obo/owl/FBbt#FBbt_00005146 FMA:70563 http://purl.org/obo/owl/FMA#FMA_70563 BTO:0000930 http://purl.org/obo/owl/BTO#BTO_0000930 neuroplacodal cell A cell of a platelike structure, especially a thickened plate of ectoderm in the early embryo, from which a sense organ develops. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0618947256 http://purl.org/obo/owl/ISBN#ISBN_0618947256 neural placode cell cell apocrine cell An apocrine cell is a secretory cell characterized loss of part of the cytoplasm during the process of secretion - secretions are budded off through the plasma membrane producing membrane bound vesicles containing the secreted substance. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0721662544 http://purl.org/obo/owl/ISBN#ISBN_0721662544 cell stem cell A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm MESH:A.11.872 http://purl.org/obo/owl/MESH#MESH_A.11.872 cell FMA:63368 http://purl.org/obo/owl/FMA#FMA_63368 single fate stem cell A stem cell that self-renews as well as give rise to a single mature cell type. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm Unipotential stem cell Unipotent stem cell cell FMA:70569 http://purl.org/obo/owl/FMA#FMA_70569 epithelial fate stem cell cell hematopoietic stem cell Markers differ between species, and two sets of markers have been described for mice. A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. Hematopoietic stem cells lack cell markers of effector cells (lin-negative). Lin-negative is defined by lacking one or more of the following cell surface markers: CD2, CD3 epsilon, CD4, CD5 ,CD8 alpha chain, CD11b, CD14, CD19, CD20, CD56, ly6G, ter119. GOC:DSD http://purl.org/obo/owl/GOC#GOC_DSD GOC:add http://purl.org/obo/owl/GOC#GOC_add GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm PMID:19022770 http://purl.org/obo/owl/PMID#PMID_19022770 hemopoietic stem cell colony forming unit hematopoietic blood forming stem cell HSC cell FMA:70337 http://purl.org/obo/owl/FMA#FMA_70337 FMA:86475 http://purl.org/obo/owl/FMA#FMA_86475 BTO:0000725 http://purl.org/obo/owl/BTO#BTO_0000725 erythroid progenitor cell A progenitor cell committed to the erythroid lineage. This cell is ter119-positive but lacks expression of other hematopoietic lineage markers (lin-negative). GOC:add http://purl.org/obo/owl/GOC#GOC_add ISBN:0721601464 http://purl.org/obo/owl/ISBN#ISBN_0721601464 blast forming unit erythroid burst forming unit erythroid colony forming unit erythroid CFU-E erythroid stem cell BFU-E cell BTO:0004911 http://purl.org/obo/owl/BTO#BTO_0004911 germ line cell Originally this term had some plant germ line cell children A cell that is within the developmental lineage of gametes and is able to pass along its genetic material to offspring. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0721662544 http://purl.org/obo/owl/ISBN#ISBN_0721662544 cell monoblast Morphology: mononuclear cell, diameter 12-20 _M, non-granular, N/C ratio 3/1 - 4/1; markers: CD11b (shared with many other myeloid cells); location: Adult: bone marrow; fetal: liver, Yolk Sac; role or process: hematopoiesis, monocyte development; lineage: hematopoietic, myeloid. A myeloid progenitor cell committed to the monocyte lineage. This cell is CD11b-positive, has basophilic cytoplasm, euchromatin, and the presence of a nucleolus. GOC:add http://purl.org/obo/owl/GOC#GOC_add PMID:1104740 http://purl.org/obo/owl/PMID#PMID_1104740 URL:http://www.clt.astate.edu/wwilliam/ http://www.clt.astate.edu/wwilliam/ URL:http://www.copewithcytokines.de http://www.copewithcytokines.de CFU-M colony forming unit macrophage monocyte stem cell cell FMA:83553 http://purl.org/obo/owl/FMA#FMA_83553 mature eosinophil Eosinophils are CD125-positive (IL-5R), GM-CSFR-positive, IL-3R-positive, VLA4-positive. They can also express MHC Class I & II, CD4, CD9, CD11a, CD11b, CD11c, CD13, CD15, CD16, CD17, CD18, CD24, CD25,CD28, CD29, CD32, CD33, CD35, CD37, CD39, CD43, CD44, CD45, CD45RB, CD45RO, CD46, CD47, CD48, CD49d, CD49f, CD50, CD52, CD53, CD54, CD55, CD58, CD59, CD62L, CD63, CD65, CD66, CD69, CD71, CD76, CD80, CD81, CD82, CD86, CD87, CD88, CD89, CD92, CD95, CD97, CD98, CD99, CD100, CD101, CD116, CD117, CD119, CD120, CD123, CD124, CD125, CD131, CD137, CD139, CD148, CD149, CD151, CD153, CD156, CD162, CD161, CD162, CD165, CD174, CD182, CD183, CD191, CD192, CD193, CD196, CD213, IL9R, ad integrin, beta-7 integrin, FceRI, IL13Ra1, TGFbR, PAFR, LTB4R, C3aR, CystLT1R, CystLT2R, fMLPR, CRTH2 (PGD2 receptor), histamine 4R, IDO, KYN, PAR-2, Siglec-8, Siglec-10, LIR1, LIR2, LIR3, LIR7, TLR7, TLR8, and VLA-4. Eosinophils can also secrete CXCL1, eotaxin-1, GM-CSF, IL-2, IL-3, IL-4, IL-5, IL-6, IL-8, IL-10, IL-12, IL-13, IL-16, IL-18, IFN-gamma, LTC4, MIP-1alpha, NGF, PAF, RANTES, substance P, TGF-alpha, TGF-beta, TNF-alpha, and VIP. A fully differentiated eosinophil, a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin. Cells are also differentiated from other granulocytes by a small nuclear-to-cytoplasm ratio (1:3). This cell type is CD49d-positive. GOC:add http://purl.org/obo/owl/GOC#GOC_add GOC:dsd http://purl.org/obo/owl/GOC#GOC_dsd GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0721601464 http://purl.org/obo/owl/ISBN#ISBN_0721601464 URL:http://www.cap.org http://www.cap.org mature eosinophil leucocyte polymorphonuclear leukocyte polymorphonuclear leucocyte mature eosinophil leukocyte mature eosinocyte cell neutrophilic myeloblast These cells are CD11b-negative, CD15-negative, CD16-negative, CD35-negative, CD49d-positive, CD68-positive, lactotransferrin-negative, and fMLP receptor-negative. They are found in the Band 3 fraction. A myeloblast committed to the neutrophil lineage. This cell type is GATA-1 positive, C/EBPa-positive, AML-1-positive, c-myb-positive and has low expression of PU.1 transcription factor. GOC:add http://purl.org/obo/owl/GOC#GOC_add ISBN:0721601464 http://purl.org/obo/owl/ISBN#ISBN_0721601464 PMID:12560239 http://purl.org/obo/owl/PMID#PMID_12560239 PMID:15514007 http://purl.org/obo/owl/PMID#PMID_15514007 neutrophilic granuloblast cell mature basophil Mature basophils are also capable of producing IL-3, IL-5, IL-6, IL-8, IL-13, IL-25, CCL22, tslp, vegf, and LTC4. A fully differentiated basophil, a granular leukocyte with an irregularly shaped, pale-staining nucleus that is partially constricted into two lobes, and with cytoplasm that contains coarse granules of variable size. Basophils contain vasoactive amines such as histamine and serotonin, which are released on appropriate stimulation. GOC:add http://purl.org/obo/owl/GOC#GOC_add GOC:dsd http://purl.org/obo/owl/GOC#GOC_dsd GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0721601464 http://purl.org/obo/owl/ISBN#ISBN_0721601464 PMID:18466030 http://purl.org/obo/owl/PMID#PMID_18466030 PMID:19231594 http://purl.org/obo/owl/PMID#PMID_19231594 PMID:20837449 http://purl.org/obo/owl/PMID#PMID_20837449 URL:http://www.cap.org http://www.cap.org mature basophil leucocyte polymorphonuclear leukocyte mature basophil leukocyte polymorphonuclear leucocyte cell CL:0000739 BTO:0001026 http://purl.org/obo/owl/BTO#BTO_0001026 thymus processed stem cell Consider using term 'pro-T cell ; CL:0000827' or the term 'thymocyte ; CL:0000893' or one of its children instead. OBSOLETE (was not defined before being made obsolete). cell bursa processed stem cell Consider using term 'pro-B cell ; CL:0000826' or the term 'immature B cell ; CL:0000816 or one of its children instead. OBSOLETE (was not defined before being made obsolete). cell neuronal stem cell Neural stem cell is characterized as an undifferentiated cell that originates from the neuroectoderm and has the capacity both to perpetually self-renew without differentiating and to generate multiple types of lineage-restricted progenitors. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm MESH:D058953 http://purl.org/obo/owl/MESH#MESH_D058953 PMID:15247488 http://purl.org/obo/owl/PMID#PMID_15247488 URL:http://en.wikipedia.org/wiki/Neural_stem_cell http://en.wikipedia.org/wiki/Neural_stem_cell neural stem cell NSC cell BTO:0002881 http://purl.org/obo/owl/BTO#BTO_0002881 FMA:86684 http://purl.org/obo/owl/FMA#FMA_86684 multi fate stem cell A stem cell that can give rise to multiple lineages of cells. GOC:add http://purl.org/obo/owl/GOC#GOC_add multifate stem cell multipotent stem cell multi-fate stem cell Multipotent cell cell FMA:84789 http://purl.org/obo/owl/FMA#FMA_84789 common myeloid progenitor CMP are reportedly CD38-positive, CD45RA-negative, and CD123-positive. A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages. These cells are CD34-positive, and express Gata-1, Gata2, C/EBPa, and Pu.1. GOC:add http://purl.org/obo/owl/GOC#GOC_add GOC:dsd http://purl.org/obo/owl/GOC#GOC_dsd GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0878932437 http://purl.org/obo/owl/ISBN#ISBN_0878932437 MESH:D023461 http://purl.org/obo/owl/MESH#MESH_D023461 PMCID:PMC2212039 http://purl.org/obo/owl/PMCID#PMCID_PMC2212039 PMID:10724173 http://purl.org/obo/owl/PMID#PMID_10724173 PMID:16551251 http://purl.org/obo/owl/PMID#PMID_16551251 CMP ISBN:0878932437 http://purl.org/obo/owl/ISBN#ISBN_0878932437 CFU-S ISBN:0878932437 http://purl.org/obo/owl/ISBN#ISBN_0878932437 cfu-gemm ISBN:0878932437 http://purl.org/obo/owl/ISBN#ISBN_0878932437 colony forming unit granulocyte, erythrocyte, macrophage, and megakaryocyte ISBN:0878932437 http://purl.org/obo/owl/ISBN#ISBN_0878932437 multipotential myeloid stem cell ISBN:0878932437 http://purl.org/obo/owl/ISBN#ISBN_0878932437 pluripotent stem cell (bone marrow) ISBN:0878932437 http://purl.org/obo/owl/ISBN#ISBN_0878932437 common myeloid precursor myeloid stem cell ISBN:0878932437 http://purl.org/obo/owl/ISBN#ISBN_0878932437 cell megakaryocyte-erythroid progenitor cell A progenitor cell committed to the megakaryocyte and erythroid lineages. GOC:add http://purl.org/obo/owl/GOC#GOC_add GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm MEP megakaryocyte/erythroid progenitor cell colony forming unit erythroid megakaryocyte CFU-EM cell common lymphoid progenitor CLP are CD7-positive, CD10-positive, CD19-negative, CD34-positive, CD45RA-positive, CD79a-negative, CD127-positive, AA4.1-positive, RAG-negative, Sca-1-low, sIgM-negative, sIgD-negative, TdT-negative, Vpre-B-negative, and pre-BCR-negative. Expression of transcription factors include E2A-positive, EBF-positive, Ikaros-negative, PU.1-negative, and Pax5-negative. A oligopotent progenitor cell committed to the lymphoid lineage. GOC:add http://purl.org/obo/owl/GOC#GOC_add GOC:dsd http://purl.org/obo/owl/GOC#GOC_dsd GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm PMID:10407577 http://purl.org/obo/owl/PMID#PMID_10407577 PMID:16551251 http://purl.org/obo/owl/PMID#PMID_16551251 common lymphocyte precursor lymphoid stem cell early lymphocyte progenitor common lymphoid precursor committed lymphopoietic stem cell lymphopoietic stem cell CLP common lymphocyte progenitor ELP cell CL:0000044 totipotent stem cell A stem cell from which all cells of the body can form. GOC:add http://purl.org/obo/owl/GOC#GOC_add GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm Totipotential stem cell cell FMA:84790 http://purl.org/obo/owl/FMA#FMA_84790 enamel secreting cell cell bone matrix secreting cell cell non-terminally differentiated cell A precursor cell with a limited number of potential fates. SANBI:mhl http://purl.org/obo/owl/SANBI#SANBI_mhl blast cell cell BTO:0000125 http://purl.org/obo/owl/BTO#BTO_0000125 FMA:84782 http://purl.org/obo/owl/FMA#FMA_84782 myoblast A precursor cell of the myogenic lineage that develops from the mesoderm. They undergo proliferation, migrate to their various sites, and then differentiate into the appropriate form of myocytes. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm MESH:A.11.635 http://purl.org/obo/owl/MESH#MESH_A.11.635 cell FBbt:00005083 http://purl.org/obo/owl/FBbt#FBbt_00005083 FMA:70335 http://purl.org/obo/owl/FMA#FMA_70335 BTO:0000222 http://purl.org/obo/owl/BTO#BTO_0000222 fibroblast These cells may be vimentin-positive, fibronectin-positive, fsp1-positive, mmp-1-positive, collagen I-positive, collagen III-positive, and alpha-SMA-negative. A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped. ISBN:0517223651 http://purl.org/obo/owl/ISBN#ISBN_0517223651 MESH:A.11.329.228 http://purl.org/obo/owl/MESH#MESH_A.11.329.228 URL:http://63.198.234.228/OpenFMA/Fibroblast.html http://63.198.234.228/OpenFMA/Fibroblast.html cell FMA:63877 http://purl.org/obo/owl/FMA#FMA_63877 BTO:0000452 http://purl.org/obo/owl/BTO#BTO_0000452 chondroblast An immature cartilage-producing cell found in growing cartilage. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0618947256 http://purl.org/obo/owl/ISBN#ISBN_0618947256 chrondoplast cell FMA:66783 http://purl.org/obo/owl/FMA#FMA_66783 BTO:0003607 http://purl.org/obo/owl/BTO#BTO_0003607 ameloblast A cylindrical epithelial cell in the innermost layer of the enamel organ. Their functions include contribution to the development of the dentinoenamel junction by the deposition of a layer of the matrix, thus producing the foundation for the prisms (the structural units of the dental enamel), and production of the matrix for the enamel prisms and interprismatic substance. (From Jablonski's Dictionary of Dentistry, 1992). GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm MESH:A.11.436.107 http://purl.org/obo/owl/MESH#MESH_A.11.436.107 cell BTO:0001663 http://purl.org/obo/owl/BTO#BTO_0001663 FMA:70576 http://purl.org/obo/owl/FMA#FMA_70576 odontoblast One of the cells forming the outer surface of dental pulp that produces tooth dentin. ISBN:0618947256 http://purl.org/obo/owl/ISBN#ISBN_0618947256 cell FMA:62999 http://purl.org/obo/owl/FMA#FMA_62999 BTO:0001769 http://purl.org/obo/owl/BTO#BTO_0001769 cementoblast A cell of ectomesenchymal origin that aids in the formation the cementum layer on the roots of teeth. ISBN:0781733901 http://purl.org/obo/owl/ISBN#ISBN_0781733901 cell FMA:63002 http://purl.org/obo/owl/FMA#FMA_63002 osteoblast A bone-forming cell which secretes an extracellular matrix. Hydroxyapatite crystals are then deposited into the matrix to form bone. MESH:A.11.329.629 http://purl.org/obo/owl/MESH#MESH_A.11.329.629 cell BTO:0001593 http://purl.org/obo/owl/BTO#BTO_0001593 FMA:66780 http://purl.org/obo/owl/FMA#FMA_66780 cell by histology A classification of cells by their microscopic appearance. FB:ma http://purl.org/obo/owl/FB#FB_ma GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm cell ciliated cell A cell that has a filiform extrusion of the cell surface. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm cell ependymal cell A neurectoderm derived cell that lines the neural lumen. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm JB:jb http://purl.org/obo/owl/JB#JB_jb PMID:9550134 http://purl.org/obo/owl/PMID#PMID_9550134 ependymocyte cell BTO:0001724 http://purl.org/obo/owl/BTO#BTO_0001724 FMA:70550 http://purl.org/obo/owl/FMA#FMA_70550 epithelial cell A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina. FB:ma http://purl.org/obo/owl/FB#FB_ma GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm MESH:A.11.436 http://purl.org/obo/owl/MESH#MESH_A.11.436 Epitheliocyte cell BTO:0000414 http://purl.org/obo/owl/BTO#BTO_0000414 FBbt:00000124 http://purl.org/obo/owl/FBbt#FBbt_00000124 FMA:66768 http://purl.org/obo/owl/FMA#FMA_66768 ciliated epithelial cell An epithelial cell that has a cillia. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm cell FMA:70605 http://purl.org/obo/owl/FMA#FMA_70605 duct epithelial cell cell branched duct epithelial cell cell epithelial cell of gland cell blood vessel endothelial cell An endothelial cell that lines the vasculature. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm Cuboidal endothelial cell of vascular tree cell non-branched duct epithelial cell cell barrier epithelial cell cell epithem cell replaced_by: PO:0000066 Obsolete. Use PO:0000066 from Plant Ontology instead. A cell that constitutes the mesophyll of a hydathode and is located between the xylem endings and the epidermis. Proposed to be involved in the retrieval of solutes from the xylem sap. ISBN:0471245208 http://purl.org/obo/owl/ISBN#ISBN_0471245208 PMID:12662305 http://purl.org/obo/owl/PMID#PMID_12662305 cell columnar/cuboidal epithelial cell cell squamous epithelial cell cell mesothelial cell A flattened epithelial cell of mesenchymal origin that lines the serous cavity. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0721662544 http://purl.org/obo/owl/ISBN#ISBN_0721662544 Mesotheliocyte cell FMA:66773 http://purl.org/obo/owl/FMA#FMA_66773 peridermal cell cell stratified epithelial cell cell circulating cell A cell which moves among different tissues of the body, via blood, lymph, or other medium. GOC:add http://purl.org/obo/owl/GOC#GOC_add cell blood cell A cell found predominately in the blood. GOC:add http://purl.org/obo/owl/GOC#GOC_add GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm cell fma:62844 http://purl.org/obo/owl/fma#fma_62844 epithelial cell of lung cell BTO:0004299 http://purl.org/obo/owl/BTO#BTO_0004299 epithelial cell of pancreas An epithelial cell of the pancreas. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm epithelial cell of exocrine pancreas exocrine pancreas cell cell BTO:0000028 http://purl.org/obo/owl/BTO#BTO_0000028 T cell A type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex. GOC:add http://purl.org/obo/owl/GOC#GOC_add GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0781735149 http://purl.org/obo/owl/ISBN#ISBN_0781735149 immature T cell T-cell mature T cell T-lymphocyte T lymphocyte cell CL:0000812 CL:0000804 BTO:0000782 http://purl.org/obo/owl/BTO#BTO_0000782 FMA:62870 http://purl.org/obo/owl/FMA#FMA_62870 germ line stem cell (sensu Vertebrata) cell germ line stem cell (sensu Nematoda and Protostomia) cell FBbt:00004861 http://purl.org/obo/owl/FBbt#FBbt_00004861 male germ line stem cell (sensu Nematoda and Protostomia) cell FBbt:00004929 http://purl.org/obo/owl/FBbt#FBbt_00004929 female germ line stem cell (sensu Nematoda and Protostomia) cell FBbt:00004873 http://purl.org/obo/owl/FBbt#FBbt_00004873 male germ line stem cell (sensu Vertebrata) cell female germ line stem cell (sensu Vertebrata) cell Kupffer cell Markers: Mouse: F4/80+, CD11b-low, CD68+, sialoadhesin+, CD163/SRCR+; role or process: immune, antigen-presentation, clearance of senescent erythro-cytes, iron metabolism. Kupffer cells are also reportedly C3aR-positive, CD14-low, CD54-positive, CD88-positve, and CD284-positive. They are also capable of producing IL-1, IL-6, TNF-alpha, nitric oxide, PGD2, PGE2, PGF2alpha, and TXA2. A tissue-resident macrophage of the reticuloendothelial system found on the luminal surface of the hepatic sinusoids involved in erythrocyte clearance. Markers include F4/80+, CD11b-low, CD68-positive, sialoadhesin-positive, CD163/SRCR-positive. Irregular, with long processes including lamellipodia extending into the sinusoid lumen, have flattened nucleus with cytoplasm containing characteristic invaginations of the plasma membrane (vermiform bodies); lie within the sinusoid lumen attached to the endothelial surface; derived from the bone marrow, form a major part of the body's mononuclear phagocyte system. GOC:add http://purl.org/obo/owl/GOC#GOC_add GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm GO_REF:0000031 http://purl.org/obo/owl/GO_REF#GO_REF_0000031 ISBN:0517223651 http://purl.org/obo/owl/ISBN#ISBN_0517223651 MESH:A.11.329.372.588 http://purl.org/obo/owl/MESH#MESH_A.11.329.372.588 PMID:15771589 http://purl.org/obo/owl/PMID#PMID_15771589 PMID:17105582 http://purl.org/obo/owl/PMID#PMID_17105582 Von Kupffer cell Hepatic macrophage Macrophagocytus stellatus Stellate cell of von Kupffer Littoral cell of hepatic sinusoid Liver macrophage cell BTO:0000685 http://purl.org/obo/owl/BTO#BTO_0000685 FMA:14656 http://purl.org/obo/owl/FMA#FMA_14656 osteoclast Morphology: Highly vesicular; markers: Surface: RANK, cFMS (MCSF receptor); Secreted: cathepsin K and TRAP (tartate resistant acid phosphatase); transcription factors: PU.1, cFOS, MITF, NFkB (p52); role or process: tissue remodelling: bone resorption; lineage: hematopoietic, myeloid. A specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, which typically differentiates from monocytes. This cell has the following markers: tartrate-resistant acid phosphatase type 5-positive, PU.1-positive, c-fos-positive, nuclear factor NF-kappa-B p100 subunit-positive, tumor necrosis factor receptor superfamily member 11A-positive and macrophage colony-stimulating factor 1 receptor-positive. GOC:add http://purl.org/obo/owl/GOC#GOC_add GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm GO_REF:0000031 http://purl.org/obo/owl/GO_REF#GO_REF_0000031 ISBN:0781735149 http://purl.org/obo/owl/ISBN#ISBN_0781735149 PMID:10428500 http://purl.org/obo/owl/PMID#PMID_10428500 PMID:15055519 http://purl.org/obo/owl/PMID#PMID_15055519 PMID:17380158 http://purl.org/obo/owl/PMID#PMID_17380158 chondroclast cell FMA:66781 http://purl.org/obo/owl/FMA#FMA_66781 BTO:0000968 http://purl.org/obo/owl/BTO#BTO_0000968 osteochondroclast Consider using 'osteoclast ; CL:0000092' instead. OBSOLETE (was not defined before being made obsolete). cell granulocyte A leukocyte with abundant granules in the cytoplasm. GOC:amm http://purl.org/obo/owl/GOC#GOC_amm GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm MESH:A.11.118.637.415 http://purl.org/obo/owl/MESH#MESH_A.11.118.637.415 Granular leukocyte polymorphonuclear leukocyte Granular leucocyte cell BTO:0001026 http://purl.org/obo/owl/BTO#BTO_0001026 BTO:0000539 http://purl.org/obo/owl/BTO#BTO_0000539 FMA:62854 http://purl.org/obo/owl/FMA#FMA_62854 neuron associated cell cell mature neutrophil Neutrophils are also capable of secreting GRO-alpha, IL-1beta, IL-1ra, IL-3, IL-12, IP-10, MIG, MIP-1alpha, MIP-1beta, TGF-beta, TNF-alpha, VEGF, and anti-microbial peptides. They can positively influence the chemotaxis of basophils, T-cells, monocytes, macrophages, dendritic cells, and other neutrophils.nNeutrophils are also CD35-positive, CD64-positive, CD89-positive, CD184-positive, and fMLP receptor-positive Ly-6G-positive (mouse), TLR2-low, TLR4-low, and lineage-negative (CD2, CD3, CD5, CD9, CD19, CD36, CD49d, CD56, CD61, CD235a (glycophorin-A)). A fully differentiated neutrophil, a granular leukocyte having a nucleus with three to five lobes connected by slender threads, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes. They are produced in bone marrow at a rate of 5e10-10e10/ day and have a half-life of 6-8 hours. Neutrophils are CD15-positive, CD16-positive, CD32-positive, CD43-positive, CD181-positive, and CD182-positive ." GOC:add http://purl.org/obo/owl/GOC#GOC_add GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm MESH:A.11.118.637.415.583 http://purl.org/obo/owl/MESH#MESH_A.11.118.637.415.583 MESH:D009504 http://purl.org/obo/owl/MESH#MESH_D009504 PMID:11138776 http://purl.org/obo/owl/PMID#PMID_11138776 PMID:12560239 http://purl.org/obo/owl/PMID#PMID_12560239 PMID:15514007 http://purl.org/obo/owl/PMID#PMID_15514007 PMID:7880385 http://purl.org/obo/owl/PMID#PMID_7880385 URL:http://www.cap.org http://www.cap.org mature neutrophil leukocyte mature neutrophilic leukocyte poly polymorphonuclear leukocyte polynuclear neutrophilic leukocyte polymorphonuclear leucocyte polynuclear neutrophilic leucocyte mature neutrophil leucocyte mature neutrocyte mature neutrophilic leucocyte PMN polymorphonuclear neutrophil cell BTO:0003473 http://purl.org/obo/owl/BTO#BTO_0003473 mast cell Mast cells are generally integrin beta-7-negative and positive for TLR2, TLR3, TLR4, TLR5, TLR7, TLR9, C3aR, C5aR, CR3, CR4, VEGF, FGF2, and renin. They can express MHC Class I and II on their surface. Activated murine mast cells (IgE+Antigen) were capable of expressing the following co-stimulatory molecules: CD95 (Fas), CD120b, CD137 (4-1BB), CD153 (CD30L), CD154 (CD40L), GITR, ICOSL, OX40L, PD-L1, and PD-L2. Note that there was some mouse strain variation. Mast cells have also been demonstrated to produce bFGF, CCL2, CCL4, CCL5, CCL11, CCL20, CXCL2, CXCL8, CXCL10, GM-CSF, IFN-gamma, IL-1, IL-2, IL-3, IL-8, IL-10, IL-11, IL-12, IL-13, IL-16, IL-25, IL-18, MIP-1, prostaglandin D2, SCF, TGF-beta, TNF-alpha, TSLP, VEGF, and XCL1. They express the transcription factors Transcription factors AP-1, GATA1, MITF, Notch2, PIAS3, PU.1, and STAT5. A cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation. Progenitors leave bone marrow and mature in connective and mucosal tissue. Mature mast cells are found in all tissues, except the bloodstream. Their phenotype is CD117-high, CD123-negative, CD193-positive, CD200R3-positive, and FceRI-high. Stem-cell factor (KIT-ligand; SCF) is the main controlling signal of their survival and development. GOC:add http://purl.org/obo/owl/GOC#GOC_add GOC:dsd http://purl.org/obo/owl/GOC#GOC_dsd GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:068340007X http://purl.org/obo/owl/ISBN#ISBN_068340007X MESH:A.11.329.427 http://purl.org/obo/owl/MESH#MESH_A.11.329.427 MESH:D008407 http://purl.org/obo/owl/MESH#MESH_D008407 PMCID:PMC1312421 http://purl.org/obo/owl/PMCID#PMCID_PMC1312421 PMCID:PMC2855166 http://purl.org/obo/owl/PMCID#PMCID_PMC2855166 PMID:15153310 http://purl.org/obo/owl/PMID#PMID_15153310 PMID:16455980 http://purl.org/obo/owl/PMID#PMID_16455980 PMID:19671378 http://purl.org/obo/owl/PMID#PMID_19671378 PMID:212366338 http://purl.org/obo/owl/PMID#PMID_212366338 PMID:9354811 http://purl.org/obo/owl/PMID#PMID_9354811 Histaminocyte tissue basophil ISBN:068340007X http://purl.org/obo/owl/ISBN#ISBN_068340007X mastocyte ISBN:0721601464 http://purl.org/obo/owl/ISBN#ISBN_0721601464 labrocyte ISBN:0721601464 http://purl.org/obo/owl/ISBN#ISBN_0721601464 cell FMA:66784 http://purl.org/obo/owl/FMA#FMA_66784 BTO:0000830 http://purl.org/obo/owl/BTO#BTO_0000830 sensory epithelial cell The term "neuroepithelial cell" is used to describe both this cell type and neurecto-epithelial cell (CL:0000710). A specialized epithelial cell involved in sensory perception. Restricted to special sense organs of the olfactory, gustatory, and vestibulocochlear receptor systems; contain sensory cells surrounded by supportive, non-receptive cells. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0517223651 http://purl.org/obo/owl/ISBN#ISBN_0517223651 ISBN:0721662544 http://purl.org/obo/owl/ISBN#ISBN_0721662544 neuroepithelial cell cell BTO:0004301 http://purl.org/obo/owl/BTO#BTO_0004301 interneuron Most generally any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region as contrasted with projection neurons which have axons projecting to other brain regions. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm MESH:A.08.663.358 http://purl.org/obo/owl/MESH#MESH_A.08.663.358 cell FMA:67313 http://purl.org/obo/owl/FMA#FMA_67313 BTO:0003811 http://purl.org/obo/owl/BTO#BTO_0003811 FBbt:00005125 http://purl.org/obo/owl/FBbt#FBbt_00005125 motor neuron An efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement. MESH:A.08.663.655.500 http://purl.org/obo/owl/MESH#MESH_A.08.663.655.500 PMID:16875686 http://purl.org/obo/owl/PMID#PMID_16875686 anterior horn cell motoneuron cell FMA:83617 http://purl.org/obo/owl/FMA#FMA_83617 BTO:0000312 http://purl.org/obo/owl/BTO#BTO_0000312 sensory neuron Any neuron having a sensory function; an afferent neuron conveying sensory impulses. ISBN:0721662544 http://purl.org/obo/owl/ISBN#ISBN_0721662544 cell BTO:0001037 http://purl.org/obo/owl/BTO#BTO_0001037 FBbt:00005124 http://purl.org/obo/owl/FBbt#FBbt_00005124 FMA:84649 http://purl.org/obo/owl/FMA#FMA_84649 polymodal neuron cell bipolar neuron A type of interneuron that has two neurites, usually an axon and a dendrite, extending from opposite poles of an ovoid cell body. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0444009442 http://purl.org/obo/owl/ISBN#ISBN_0444009442 cell FMA:67282 http://purl.org/obo/owl/FMA#FMA_67282 multipolar neuron Neuron with an axon and two or more dendrites. FMA:67287 http://purl.org/obo/owl/FMA#FMA_67287 GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm cell pseudounipolar neuron Neuron with two neurites that are fused grossly when they protrude from the soma and bifurcate a short distance from the soma. FMA:67305 http://purl.org/obo/owl/FMA#FMA_67305 GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm cell unipolar neuron Neuron with an axon and no dendrites. FMA:67278 http://purl.org/obo/owl/FMA#FMA_67278 cell autonomic neuron A neruon whose cell body is within an autonomic ganglion. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm cell FMA:80121 http://purl.org/obo/owl/FMA#FMA_80121 cholinergic neuron A neuron that uses acetylcholine as a vesicular neurotransmitter. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm cell WBbt:0006840 http://purl.org/obo/owl/WBbt#WBbt_0006840 BTO:0004902 http://purl.org/obo/owl/BTO#BTO_0004902 FMA:84796 http://purl.org/obo/owl/FMA#FMA_84796 adrenergic neuron cell peptidergic neuron cell peripheral neuron A neuron that is part of nerve found outside the central nervous system. ISBN:0721662544 http://purl.org/obo/owl/ISBN#ISBN_0721662544 cell FMA:84664 http://purl.org/obo/owl/FMA#FMA_84664 columnar neuron columnar neuron cell mononuclear phagocyte A vertebrate phagocyte with a single nucleus. GOC:add http://purl.org/obo/owl/GOC#GOC_add GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0781735149 http://purl.org/obo/owl/ISBN#ISBN_0781735149 cell BTO:0001433 http://purl.org/obo/owl/BTO#BTO_0001433 surface ectodermal cell surface ectoderm cell cell of surface ectoderm cell FMA:72552 http://purl.org/obo/owl/FMA#FMA_72552 endothelial cell From FMA: n9.07.2001: Endothelial cell has always been classified as a kind of epithelial cell, specifically a squamous cell but that is not true. First, endothelial cell can either be squamous or cuboidal (e.g. high-endothelial cell) and secondly, it has different embryological derivation (mesodermal) than a true epithelial cell (ectodermal and endodermal). The basis for present classifiaction is the fact that it comprises the outermost layer or lining of anatomical structures (location-based) but a better structural basis for the differentia is the cytoskeleton of the cell. Endothelial cell has vimentin filaments while an epithelial cell has keratin filaments. [Onard] An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. In mammals, endothelial cell has vimentin filaments and is derived from the mesoderm. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm MESH:D042783 http://purl.org/obo/owl/MESH#MESH_D042783 URL:http://63.198.234.228/OpenFMA/Endothelial%20cell.html http://63.198.234.228/OpenFMA/Endothelial%20cell.html Endotheliocyte cell BTO:0001176 http://purl.org/obo/owl/BTO#BTO_0001176 FMA:66772 http://purl.org/obo/owl/FMA#FMA_66772 pioneer neuron Pioneer neurons establish a pathway in the developing central nervous system and then undergo programmed cell death once the adult axons, which follow them, have made connections with the target site. Thus, they are a transient cell type involved in axon guidance. GOC:cvs http://purl.org/obo/owl/GOC#GOC_cvs GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm cell FBbt:00005128 http://purl.org/obo/owl/FBbt#FBbt_00005128 CNS neuron (sensu Vertebrata) cell basket cell cell Golgi cell cell granule cell cell BTO:0003393 http://purl.org/obo/owl/BTO#BTO_0003393 Purkinje cell The output neuron of the cerebellar cortex. MESH:A.08.186.211.132.810.428.200.212.600 http://purl.org/obo/owl/MESH#MESH_A.08.186.211.132.810.428.200.212.600 Purkinje's cell Purkinje neuron cell FMA:67969 http://purl.org/obo/owl/FMA#FMA_67969 BTO:0001011 http://purl.org/obo/owl/BTO#BTO_0001011 stellate cell cell BTO:0002316 http://purl.org/obo/owl/BTO#BTO_0002316 neuron associated cell (sensu Vertebrata) cell glial cell (sensu Nematoda and Protostomia) cell FBbt:00005144 http://purl.org/obo/owl/FBbt#FBbt_00005144 glial cell A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Guide neuronal migration during development, and exchange metabolites with neurons. MESH:A.08.637 http://purl.org/obo/owl/MESH#MESH_A.08.637 neuroglia neuroglial cell cell FMA:54536 http://purl.org/obo/owl/FMA#FMA_54536 BTO:0002606 http://purl.org/obo/owl/BTO#BTO_0002606 macroglial cell A neuroglial cell of ectodermal origin, i.e., the astrocytes and oligodendrocytes considered together. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0721662544 http://purl.org/obo/owl/ISBN#ISBN_0721662544 Macrogliocyte cell FMA:54538 http://purl.org/obo/owl/FMA#FMA_54538 BTO:0000771 http://purl.org/obo/owl/BTO#BTO_0000771 astrocyte Astrocytes are reportedly CD68-negative, CD121a-positive, CD184-positive, CD192-positive, CRF-positive, EGFR-positive, GFAP-positive, GLUT1-positive, MBP-negative, and NGFR-positive. A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from 'star' cells) are irregularly shaped with many long processes, including those with 'end feet' which form the glial (limiting) membrane and directly and indirectly contribute to the blood-brain barrier. They regulate the extracellular ionic and chemical environment, and 'reactive astrocytes' (along with microglia) respond to injury. GOC:_tfm http://purl.org/obo/owl/GOC#GOC__tfm GOC:dsd http://purl.org/obo/owl/GOC#GOC_dsd MESH:A.08.637.200 http://purl.org/obo/owl/MESH#MESH_A.08.637.200 MESH:D001253 http://purl.org/obo/owl/MESH#MESH_D001253 PMID:11746784 http://purl.org/obo/owl/PMID#PMID_11746784 PMID:12162730 http://purl.org/obo/owl/PMID#PMID_12162730 PMID:12898703 http://purl.org/obo/owl/PMID#PMID_12898703 PMID:20942978 http://purl.org/obo/owl/PMID#PMID_20942978 astrocytic glia cell BTO:0000099 http://purl.org/obo/owl/BTO#BTO_0000099 FMA:54537 http://purl.org/obo/owl/FMA#FMA_54537 oligodendrocyte A class of large neuroglial (macroglial) cells in the central nervous system. Form the insulating myelin sheath of axons in the central nervous system. MESH:A.08.637.600 http://purl.org/obo/owl/MESH#MESH_A.08.637.600 oligodendroglia cell FMA:54540 http://purl.org/obo/owl/FMA#FMA_54540 BTO:0000962 http://purl.org/obo/owl/BTO#BTO_0000962 microglial cell Markers: Mouse: CD11b+, F4/80+, CD68+. They represent ~12% of the cells in the CNS, but they are not uniformly distributed within the CNS. A normal adult mouse brain has approximately 3.5x10e6 microglia. Microglia are also reportedly CD3-negative, CD4-positive, CD8-negative, CD11b-positive, CD19-negative, CD56-negative, CD163-negative, CD200R-positive, CD281-positive, CD282-positive, CD283-positive, CD284-positive, CD285-positive, CD286-positive, CD287-positive, CD288-positive, CD289-positive, Gr1-negative, nestin-positive, and PU.1-positive. A central nervous system macrophage found in the parenchyma of the central nervous system. Marker include CD11b-positive, F4/80-positive, and CD68-positive. GOC:add http://purl.org/obo/owl/GOC#GOC_add GOC:dsd http://purl.org/obo/owl/GOC#GOC_dsd GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0721601464 http://purl.org/obo/owl/ISBN#ISBN_0721601464 MESH:D017628 http://purl.org/obo/owl/MESH#MESH_D017628 PMID:11517395 http://purl.org/obo/owl/PMID#PMID_11517395 PMID:12430718 http://purl.org/obo/owl/PMID#PMID_12430718 PMID:14561199 http://purl.org/obo/owl/PMID#PMID_14561199 PMID:14612429 http://purl.org/obo/owl/PMID#PMID_14612429 PMID:16177057 http://purl.org/obo/owl/PMID#PMID_16177057 PMID:19461673 http://purl.org/obo/owl/PMID#PMID_19461673 PMID:2089275 http://purl.org/obo/owl/PMID#PMID_2089275 brain macrophage brain-resident macrophage MF.microglia.CNS hortega cells URL:http://www.copewithcytokines.de/ http://www.copewithcytokines.de/ microgliocyte URL:http://www.copewithcytokines.de/ http://www.copewithcytokines.de/ microglia cell BTO:0000962 http://purl.org/obo/owl/BTO#BTO_0000962 BTO:0000078 http://purl.org/obo/owl/BTO#BTO_0000078 FMA:54540 http://purl.org/obo/owl/FMA#FMA_54540 FMA:54539 http://purl.org/obo/owl/FMA#FMA_54539 neuron associated cell (sensu Nematoda and Protostomia) cell gut endothelial cell cell corneal endothelial cell Cell of the single layer of large flattened cells covering the surface of the cornea. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm MESH:A.09.371.060.067.31 http://purl.org/obo/owl/MESH#MESH_A.09.371.060.067.31 cell FMA:70614 http://purl.org/obo/owl/FMA#FMA_70614 neurectodermal cell Ectoderm destined to be nervous tissue. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:068340007X http://purl.org/obo/owl/ISBN#ISBN_068340007X neurectoderm cell cell mesenchymal cell Many but not all mesenchymal cells derive from the mesoderm. MSCs are reportedly CD3-negative, CD4-negative, CD5-negative, CD8-negative, CD11a-negative, CD11b-negative, CD14-negative, CD19-negative, CD29-positive, CD31-negative, CD34-negative, CD38-negative, CD40-negative, CD44-positive, CD45-negative, CD49-positive, CD54-positive, CD66b-negative, CD79a-negative, CD80-negative, CD102-positive, CD106-positive, CD117-positive, CD121a-positive, CD121b-positive, CD123-positive, CD124-positive, CD133-negative, CD146-positive, CD166-positive, CD271-positive, B220-negative, Gr1-negative, MHCI-positive, MHCII-negative, SSEA4-negative, sca1-positive, Ter119-negative, and glycophorin A-negative. Cultured MSCs are capable of producing stem cell factor, IL7, IL8, IL11, TGF-beta, cofilin, galectin-1, laminin-receptor 1, cyclophilin A, and MMP-2. A connective tissue cell that normally gives rise to other cells that are organized as three-dimensional masses. This cell type is CD73-positive, CD90-positive, CD105-positive, CD45-negative, CD34-negative, and MHCII-negative. They may further differentiate into osteoblasts, adipocytes, myocytes, neurons, or chondroblasts in vitro. Originally described as residing in the bone marrow, this cell type is now known to reside in many, if not all, adult organs. FB:ma http://purl.org/obo/owl/FB#FB_ma GOC:dsd http://purl.org/obo/owl/GOC#GOC_dsd PMCID:PMC2613570 http://purl.org/obo/owl/PMCID#PMCID_PMC2613570 PMID:_17986482 http://purl.org/obo/owl/PMID#PMID__17986482 PMID:_19960544 http://purl.org/obo/owl/PMID#PMID__19960544 PMID:10102814j http://purl.org/obo/owl/PMID#PMID_10102814j PMID:16923606 http://purl.org/obo/owl/PMID#PMID_16923606 URL:http://en.wikipedia.org/wiki/Mesenchymal_stem_cell http://en.wikipedia.org/wiki/Mesenchymal_stem_cell URL:http://www.copewithcytokines.de/cope.cgi?key=mesenchymal%20stem%20cells http://www.copewithcytokines.de/cope.cgi?key=mesenchymal%20stem%20cells mesenchymal stromal cells MSC PMID:11378515 http://purl.org/obo/owl/PMID#PMID_11378515 Stem Cells, Mesenchymal MESH:D044982 http://purl.org/obo/owl/MESH#MESH_D044982 bone marrow stromal cells mesenchymal stem cell BMSC mesenchymal precursor cell colony-forming unit-fibroblast mesenchymal stromal cell CFU-F marrow stromal cells PMID:11378515 http://purl.org/obo/owl/PMID#PMID_11378515 mesenchymal progenitor cells MESH:D044982 http://purl.org/obo/owl/MESH#MESH_D044982 cell CL:0002452 BTO:0002625 http://purl.org/obo/owl/BTO#BTO_0002625 FMA:70546 http://purl.org/obo/owl/FMA#FMA_70546 BTO:0003298 http://purl.org/obo/owl/BTO#BTO_0003298 fibrocyte Cultured human fibrocytes are MHCI-positive, MHCII-positive, CD1a-negative, CD3-negative, CD4-negative, CD8-negative, CD10-negative, CD11b-positive, CD13-positive, CD14-negative, CD16-negative, CD18-positive, CD19-negative, CD25-negative, CD29-positive, CD32-positive, CD33-negative, CD34-positive, CD38-negative, CD40-positive, CD44-negative, CD45RO-positive, CD49a-positive, CD49b-positive, CD49c-negative, CD49d-negative, CD49e-positive, CD49f-negative, CD56-negative, CD58-positive, CD61-positive, CD64-positive, CD70-negative, CD71-positive, CD80-positive, CD83-negative, CD86-positive, CD103-negative, CD105-positive, CD181-positive, CD182-negative, CD183-positive, CD184-positive, CD185-negative, CD186-negative, CD191-positive, CD192-negative, CD193-positive, CD194-positive, CD195-positive, CD196-negative, CD197-positive, CD199-positive, desmin-negative, F4/80-positive, Gr1-positive, LSP-1-positive, MHCI-positive, MHCII-positive, alpha-SMA-negative, TCRab-negative, TCRgd-negative, and vimentin-positive. Fibrocytes are also capable of secreting angiogenin, bFGF, CCL2, CCL3, CCL4, CCL8, CXCL1, type I collagen, type III collagen, CTGF, fibronectin, GM-CSF, IL-1a, IL-6, IL-8, IL-10, M-CSF, MMP-9, PDGF-A, TGF-alpha, TGF-beta1, TNF-alpha, VEGF-A, and type I collagen. An inactive fibroblast; cytoplasm is sparse, endoplasmic reticulum is scanty with flattened nucleus. Term used by some histologists; when fibroblasts become relatively inactive in fiber formation. However, this cell has the potential for fibrogenesis in quiescent connective tissue of the adult, as well as during development, other histologists prefer to use the term fibroblast in all circumstances. These cells represent ~0.5% of peripheral blood leukocytes. GOC:dsd http://purl.org/obo/owl/GOC#GOC_dsd GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0412046911 http://purl.org/obo/owl/ISBN#ISBN_0412046911 ISBN:0517223651 http://purl.org/obo/owl/ISBN#ISBN_0517223651 PMID:11641248 http://purl.org/obo/owl/PMID#PMID_11641248 PMID:15010326 http://purl.org/obo/owl/PMID#PMID_15010326 PMID:17607298 http://purl.org/obo/owl/PMID#PMID_17607298 PMID:18222966 http://purl.org/obo/owl/PMID#PMID_18222966 PMID:8790603 http://purl.org/obo/owl/PMID#PMID_8790603 PMID:9551999 http://purl.org/obo/owl/PMID#PMID_9551999 cell FMA:63879 http://purl.org/obo/owl/FMA#FMA_63879 fat cell A fat-storing cell found mostly in the abdominal cavity and subcutaneous tissue of mammals. Fat is usually stored in the form of triglycerides. MESH:A.11.329.114 http://purl.org/obo/owl/MESH#MESH_A.11.329.114 adipocyte adipose cell cell CL:0000450 FMA:63880 http://purl.org/obo/owl/FMA#FMA_63880 BTO:0000443 http://purl.org/obo/owl/BTO#BTO_0000443 osteocyte A mature osteoblast that has become embedded in the bone matrix. They occupy a small cavity, called lacuna, in the matrix and are connected to adjacent osteocytes via protoplasmic projections called canaliculi. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm MESH:A.11.329.629.500 http://purl.org/obo/owl/MESH#MESH_A.11.329.629.500 bone cell cell FMA:66779 http://purl.org/obo/owl/FMA#FMA_66779 BTO:0002038 http://purl.org/obo/owl/BTO#BTO_0002038 chondrocyte Polymorphic cell that form cartilage. MESH:A.11.329.171 http://purl.org/obo/owl/MESH#MESH_A.11.329.171 cartilage cell cell BTO:0000249 http://purl.org/obo/owl/BTO#BTO_0000249 FMA:66782 http://purl.org/obo/owl/FMA#FMA_66782 amelocyte cell odontocyte cell cementocyte An osteocytelike cell with numerous processes, trapped in a lacuna in the cement of the tooth. ISBN:0781733901 http://purl.org/obo/owl/ISBN#ISBN_0781733901 cell FMA:63003 http://purl.org/obo/owl/FMA#FMA_63003 hyalocyte A cell occurring in the peripheral part of the vitreous body of the eye that may be responsible for production of hyaluronic acid and collagen. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm PMID:19073178 http://purl.org/obo/owl/PMID#PMID_19073178 vitreous cell cell BTO:0004271 http://purl.org/obo/owl/BTO#BTO_0004271 FMA:70620 http://purl.org/obo/owl/FMA#FMA_70620 guidepost cell cell cell by function A classification of cells by their primary end goal or behavior. FB:ma http://purl.org/obo/owl/FB#FB_ma cell professional antigen presenting cell Note change of name; nearly all somatic cells can present antigens to T cells via MHC Class I complexes leading to effector responses, but professional antigen presenting cells constituitively express MHC Class II as well as constimulatory molecules, and thus can initiate immune responses via T cells. A cell capable of processing and presenting lipid and protein antigens to T cells in order to initiate an immune response. GOC:add http://purl.org/obo/owl/GOC#GOC_add ISBN:0781735149 http://purl.org/obo/owl/ISBN#ISBN_0781735149 APC cell simple columnar epithelial cell cell pigment cell A pigment cell is a cell that contains pigment granules. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm chromatocyte chromatophore cell melanocyte A pigment cell derived from the neural crest. Contains melanin-filled pigment granules, which gives a brown to black appearance. SANBI:mhl http://purl.org/obo/owl/SANBI#SANBI_mhl melanophore cell CL:0000572 FMA:70545 http://purl.org/obo/owl/FMA#FMA_70545 BTO:0000847 http://purl.org/obo/owl/BTO#BTO_0000847 visual pigment cell pigment cell cell glandular epithelial cell A specialized epithelial cell that is capable of synthesizing and secreting certain biomolecules. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm cell FMA:86494 http://purl.org/obo/owl/FMA#FMA_86494 secretory cell A cell that specializes in controlled release of one or more substances. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0721662544 http://purl.org/obo/owl/ISBN#ISBN_0721662544 cell BTO:0003659 http://purl.org/obo/owl/BTO#BTO_0003659 FMA:86916 http://purl.org/obo/owl/FMA#FMA_86916 exocrine cell A cell of an exocrine gland, i.e. a gland that discharges its secretion via a duct. ISBN:0198547684 http://purl.org/obo/owl/ISBN#ISBN_0198547684 cell FMA:16014 http://purl.org/obo/owl/FMA#FMA_16014 GAG secreting cell A cell that secretes glycosaminoglycans. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm hyaluronic acid secreting cell cell protein secreting cell cell peptic cell A cell that is usually basal in position, cuboidal with round nucleus, short microvilli, secretes pepsinogen. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm chief cell of stomach pepsinogen secreting cell peptic cell gastric chief cell zymogenic cell cell FMA:62902 http://purl.org/obo/owl/FMA#FMA_62902 antibody secreting cell Consider using 'B cell ; CL:0000236' or one of its children instead. OBSOLETE: A cell of the lymphoid series that can react with antigen to produce specific cell products called antibodies. Various cell subpopulations, often B cells, can be defined, based on the different classes of immunoglobulins that they synthesize. cell surfactant secreting cell A cell that specializes in secretion of surfactant in the alveoli of the lung. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0721662544 http://purl.org/obo/owl/ISBN#ISBN_0721662544 cell Clara cell Epithelial progenitor cell of the lung. Clara cells are dome-shaped with short microvilli but no cilia. They function to protect the bronchiolar epithelium. Clara cells also multiply and differentiate into ciliated cells to regenerate the bronchiolar epithelium. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm PMID:12107102 http://purl.org/obo/owl/PMID#PMID_12107102 PMID:7905712 http://purl.org/obo/owl/PMID#PMID_7905712 Clara cell of bronchiole Bronchiolar non-ciliated Clara cell cell FMA:14119 http://purl.org/obo/owl/FMA#FMA_14119 BTO:0004811 http://purl.org/obo/owl/BTO#BTO_0004811 seromucus secreting cell cell goblet cell A cell of the epithelial lining that produce and secrete mucins. MESH:A.03.492.411.369.320 http://purl.org/obo/owl/MESH#MESH_A.03.492.411.369.320 chalice cell cell FMA:13148 http://purl.org/obo/owl/FMA#FMA_13148 BTO:0001540 http://purl.org/obo/owl/BTO#BTO_0001540 acid secreting cell cell parietal cell A large, oval stomach epithelial cell with a central nucleus; source of gastric acid. Secretes HCl. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0517223651 http://purl.org/obo/owl/ISBN#ISBN_0517223651 oxyntic cell cell FMA:62901 http://purl.org/obo/owl/FMA#FMA_62901 BTO:0001780 http://purl.org/obo/owl/BTO#BTO_0001780 endocrine cell A cell of an endocrine gland, ductless glands that secrete substances which are released directly into the circulation and which influence metabolism and other body functions. MESH:A.06.407 http://purl.org/obo/owl/MESH#MESH_A.06.407 endocrinocyte cell FMA:83809 http://purl.org/obo/owl/FMA#FMA_83809 enteroendocrine cell An endocrine cell that is located in the epithelium of the gastrointestinal tract or in the pancreas. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm SANBI:mhl http://purl.org/obo/owl/SANBI#SANBI_mhl cell FMA:62930 http://purl.org/obo/owl/FMA#FMA_62930 BTO:0003865 http://purl.org/obo/owl/BTO#BTO_0003865 neuroendocrine cell An endocrine cell that has the specialized function to produce and secrete hormones in response to neuronal signals. MESH:A.06.688 http://purl.org/obo/owl/MESH#MESH_A.06.688 neurosecretory cell cell FMA:83810 http://purl.org/obo/owl/FMA#FMA_83810 BTO:0002691 http://purl.org/obo/owl/BTO#BTO_0002691 chromaffin cell A cell that stores epinephrine secretory vesicles. During times of stress, the nervous system signals the vesicles to secrete their hormonal content. Their name derives from their ability to stain a brownish color with chromic salts. Characteristically, they are located in the adrenal medulla and paraganglia of the sympathetic nervous system. MESH:A.06.224.161 http://purl.org/obo/owl/MESH#MESH_A.06.224.161 phaeochromocyte cell FMA:69263 http://purl.org/obo/owl/FMA#FMA_69263 BTO:0000259 http://purl.org/obo/owl/BTO#BTO_0000259 peptide hormone secreting cell cell insulin secreting cell cell BTO:0000783 http://purl.org/obo/owl/BTO#BTO_0000783 type B pancreatic cell Pancreatic beta cells are also reportedly CD284-positive. Upon activation, they upregulate their CD14 expression. A cell that secretes insulin and is located towards the center of the islets of Langerhans. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0517223651 http://purl.org/obo/owl/ISBN#ISBN_0517223651 pancreatic B cell B-cell of pancreatic islet FMA:70586 http://purl.org/obo/owl/FMA#FMA_70586 pancreatic beta cell type B enteroendocrine cell FMA:70586 http://purl.org/obo/owl/FMA#FMA_70586 pancreatic B-cell FMA:70586 http://purl.org/obo/owl/FMA#FMA_70586 pancreatic beta cell FMA:70586 http://purl.org/obo/owl/FMA#FMA_70586 insulin-secreting cell FMA:70586 http://purl.org/obo/owl/FMA#FMA_70586 beta cell of pancreatic islet FMA:70586 http://purl.org/obo/owl/FMA#FMA_70586 beta cell islet MA:0002419 http://purl.org/obo/owl/MA#MA_0002419 pancreatic islet core MA:0002419 http://purl.org/obo/owl/MA#MA_0002419 cell MA:0002419 http://purl.org/obo/owl/MA#MA_0002419 FMA:70586 http://purl.org/obo/owl/FMA#FMA_70586 BTO:0000783 http://purl.org/obo/owl/BTO#BTO_0000783 glucagon secreting cell A cell that secretes glucagon. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm Glucagon-secreting cell cell FMA:84045 http://purl.org/obo/owl/FMA#FMA_84045 pancreatic A cell A type of enteocrine cell found in the periphery of the islets of Langerhans that secretes glucagon. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0721662544 http://purl.org/obo/owl/ISBN#ISBN_0721662544 pancreatic alpha cell cell BTO:0000990 http://purl.org/obo/owl/BTO#BTO_0000990 FMA:70585 http://purl.org/obo/owl/FMA#FMA_70585 somatostatin secreting cell cell pancreatic D cell A D cell located in the pancreas. Peripherally placed within the islets like type A cells; contains somatostatin. FMA:0517223651 http://purl.org/obo/owl/FMA#FMA_0517223651 GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm Pancreatic D-cell Delta cell of islet Pancreatic delta cell pancreatic delta cell Delta cell of pancreatic islet D-cell of pancreatic islet Somatostatin-secreting pancreatic cell cell BTO:0000803 http://purl.org/obo/owl/BTO#BTO_0000803 FMA:70587 http://purl.org/obo/owl/FMA#FMA_70587 steroid hormone secreting cell cell luteal cell A progesterone secreting cell in the corpus luteum. The large luteal cells develop from the granulosa cells. The small luteal cells develop from the theca cells. MESH:A.05.360.319.114.630.278.400 http://purl.org/obo/owl/MESH#MESH_A.05.360.319.114.630.278.400 lutein cell cell FMA:18688 http://purl.org/obo/owl/FMA#FMA_18688 BTO:0003939 http://purl.org/obo/owl/BTO#BTO_0003939 ecdysteroid secreting cell cell testosterone secreting cell cell Leydig cell A Leydig cell is a testosterone-secreting cell in the interstitial area, between the seminiferous tubules, in the testis. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm PMID:12050120 http://purl.org/obo/owl/PMID#PMID_12050120 interstitial cell cell FMA:72297 http://purl.org/obo/owl/FMA#FMA_72297 BTO:0000755 http://purl.org/obo/owl/BTO#BTO_0000755 progesterone secreting cell cell estradiol secreting cell cell metabolising cell A cell whose primary function is intermediary metabolism. FB:ma http://purl.org/obo/owl/FB#FB_ma cell hepatocyte The main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules. Majority of cell population of liver, polygonal in shape, arranged in plates or trabeculae between sinusoids; may have single nucleus or binucleated. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0412046911 http://purl.org/obo/owl/ISBN#ISBN_0412046911 MESH:A.11.436.348 http://purl.org/obo/owl/MESH#MESH_A.11.436.348 PMID:19717280 http://purl.org/obo/owl/PMID#PMID_19717280 cell FMA:14515 http://purl.org/obo/owl/FMA#FMA_14515 BTO:0000575 http://purl.org/obo/owl/BTO#BTO_0000575 contractile cell A cell whose primary function is to shorten. FB:ma http://purl.org/obo/owl/FB#FB_ma cell myoepithelial cell Contractile cells resembling smooth muscle cells that are present in glands, notably the mammary gland, and aid in secretion. This cell has long weaving dendritic processes containing myofilament. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0721662544 http://purl.org/obo/owl/ISBN#ISBN_0721662544 basket epithelial cell Myoepitheliocyte cell FMA:67799 http://purl.org/obo/owl/FMA#FMA_67799 BTO:0002309 http://purl.org/obo/owl/BTO#BTO_0002309 myofibroblast cell Myofibroblasts are alpha-SMA-positive, CD34-negative, CD45-negative. They are reportedly capable of secreting IL-1beta, IL-6, and TNF-alpha. An animal cell that has characteristics of both a fibroblast cell and a smooth muscle cell. GOC:dsd http://purl.org/obo/owl/GOC#GOC_dsd GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm MESH:D058628 http://purl.org/obo/owl/MESH#MESH_D058628 PMID:19800625 http://purl.org/obo/owl/PMID#PMID_19800625 PMID:20630469 http://purl.org/obo/owl/PMID#PMID_20630469 MFB PMID:_8731193 http://purl.org/obo/owl/PMID#PMID__8731193 cell muscle cell A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns. MESH:A.11.620 http://purl.org/obo/owl/MESH#MESH_A.11.620 myocyte cell FBbt:00005074 http://purl.org/obo/owl/FBbt#FBbt_00005074 BTO:0000888 http://purl.org/obo/owl/BTO#BTO_0000888 BTO:0000902 http://purl.org/obo/owl/BTO#BTO_0000902 FMA:67328 http://purl.org/obo/owl/FMA#FMA_67328 skeletal muscle cell A somatic cell located in skeletal muscle. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm cell FMA:9727 http://purl.org/obo/owl/FMA#FMA_9727 BTO:0004392 http://purl.org/obo/owl/BTO#BTO_0004392 slow muscle cell A muscle cell that develops tension more slowly than a fast-twitch fiber. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0323052908 http://purl.org/obo/owl/ISBN#ISBN_0323052908 slow muscle fiber ISBN:0815316208 http://purl.org/obo/owl/ISBN#ISBN_0815316208 cell FMA:84448 http://purl.org/obo/owl/FMA#FMA_84448 fast muscle cell A muscle cell that can develop high tension rapidly. It is usually innervated by a single alpha neuron . GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0323052908 http://purl.org/obo/owl/ISBN#ISBN_0323052908 glycolytic muscle fiber cell smooth muscle cell A non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. They develop from specialized myoblasts (smooth muscle myoblast). MESH:A.11.620.520 http://purl.org/obo/owl/MESH#MESH_A.11.620.520 MESH:D032389 http://purl.org/obo/owl/MESH#MESH_D032389 PMID:9315361 http://purl.org/obo/owl/PMID#PMID_9315361 smooth muscle fiber SMCs PMID:9315361 http://purl.org/obo/owl/PMID#PMID_9315361 myocytes, smooth muscle MESH:D032389 http://purl.org/obo/owl/MESH#MESH_D032389 non-striated muscle cell cell CL:0000191 BTO:0004576 http://purl.org/obo/owl/BTO#BTO_0004576 FMA:14072 http://purl.org/obo/owl/FMA#FMA_14072 cardiac muscle cell (sensu Arthopoda) A striated muscle cell found in the heart. They develop from cardiac myoblasts. MESH:A.11.620.500 http://purl.org/obo/owl/MESH#MESH_A.11.620.500 cell CL:0000466 nodal cardiac cell Consider CL:0002072. cell Purkinje fiber cell flight muscle cell cell receptor cell cell pain receptor cell The peripheral receptor for pain. Includes receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli. All mammalian nociceptors are free nerve endings. MESH:A.08.800.550.700.650 http://purl.org/obo/owl/MESH#MESH_A.08.800.550.700.650 nociceptor nocireceptor cell mechanoreceptor cell A cell specialized to transduce mechanical stimuli and relay that information centrally in the nervous system. MESH:A.08.800.550.700.500 http://purl.org/obo/owl/MESH#MESH_A.08.800.550.700.500 cell touch receptor cell cell auditory hair cell In mammals these cells are located in the organ of Corti. A mechanoreceptor cell located in the inner ear that is sensitive to auditory stimuli. The accessory sensory structures are arranged so that appropriate stimuli cause movement of the hair-like projections (stereocilia and kinocilia) which relay the information centrally in the nervous system. MESH:A.08.663.650.250 http://purl.org/obo/owl/MESH#MESH_A.08.663.650.250 cochlear hair cell auditory receptor cell cell CL:0000201 FMA:62364 http://purl.org/obo/owl/FMA#FMA_62364 gravity sensitive cell cell acceleration receptive cell cell thermoreceptor cell A cellular receptor which mediates the sense of temperature. Thermoreceptor cells in vertebrates are mostly located under the skin. In mammals there are separate types of thermoreceptors for cold and for warmth and pain receptor cells which detect cold or heat extreme enough to cause pain. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm MESH:A.08.800.550.700.840 http://purl.org/obo/owl/MESH#MESH_A.08.800.550.700.840 MP:0000971 http://purl.org/obo/owl/MP#MP_0000971 cell chemoreceptor cell A cell specialized to detect chemical substances and relay that information centrally in the nervous system. Chemoreceptors may monitor external stimuli, as in taste and olfaction, or internal stimuli, such as the concentrations of oxygen and carbon dioxide in the blood. MESH:A.08.800.550.700.120 http://purl.org/obo/owl/MESH#MESH_A.08.800.550.700.120 cell olfactory receptor cell Schultze's cell olfactory receptor neuron olfactory sensory neuron cell FMA:67860 http://purl.org/obo/owl/FMA#FMA_67860 BTO:0004185 http://purl.org/obo/owl/BTO#BTO_0004185 pH receptor cell cell taste receptor cell A cell type found in the spherical or ovoid clusters of receptor cells found mainly in the epithelium of the tongue and constituting the end organs of the sense of taste. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0618947256 http://purl.org/obo/owl/ISBN#ISBN_0618947256 taste bud cell cell FMA:67910 http://purl.org/obo/owl/FMA#FMA_67910 photoreceptor cell A cell specialized to detect and transduce light. MESH:A.08.663.650.650 http://purl.org/obo/owl/MESH#MESH_A.08.663.650.650 cell BTO:0001060 http://purl.org/obo/owl/BTO#BTO_0001060 FMA:86740 http://purl.org/obo/owl/FMA#FMA_86740 FBbt:00004211 http://purl.org/obo/owl/FBbt#FBbt_00004211 electrically active cell A cell whose function is determined by the generation or the reception of an electric signal. FB:ma http://purl.org/obo/owl/FB#FB_ma cell absorptive cell A cell that takes up and metabolizes substances. CL:CVS http://purl.org/obo/owl/CL#CL_CVS cell lining cell A cell within an epithelial cell sheet whose main function is to act as an internal or external covering for a tissue or an organism. JB:jb http://purl.org/obo/owl/JB#JB_jb boundary cell cell synovial cell A meso-epithelial cell that lies between the cartilaginous fibers in the synovial membrane of a joint and produces hyaluronic acid. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0721662544 http://purl.org/obo/owl/ISBN#ISBN_0721662544 PMID:17942474 http://purl.org/obo/owl/PMID#PMID_17942474 Synoviocyte Hyaluronic acid secreting cell cell BTO:0003652 http://purl.org/obo/owl/BTO#BTO_0003652 FMA:66786 http://purl.org/obo/owl/FMA#FMA_66786 barrier cell A cell whose primary function is to prevent the transport of stuff across compartments. JB:jb http://purl.org/obo/owl/JB#JB_jb cell Sertoli cell A supporting cell projecting inward from the basement membrane of seminiferous tubules. They surround and nourish the developing male germ cells and secrete androgen binding protein. Their tight junctions with the spermatogonia and spermatocytes provide a blood-testis barrier. MESH:A.05.360.444.849.789 http://purl.org/obo/owl/MESH#MESH_A.05.360.444.849.789 cell BTO:0001238 http://purl.org/obo/owl/BTO#BTO_0001238 FMA:72298 http://purl.org/obo/owl/FMA#FMA_72298 insulating cell cell myelinating Schwann cell A neuroglial cell of the peripheral nervous system which forms the insulating myelin sheaths of peripheral axons. GOC:cvs http://purl.org/obo/owl/GOC#GOC_cvs GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm MESH:A.08.637.800 http://purl.org/obo/owl/MESH#MESH_A.08.637.800 neurilemmal cell Peripheral neuroglial cell Schwann cell cell FMA:62121 http://purl.org/obo/owl/FMA#FMA_62121 motile cell A cell that moves by its own activities. FB:ma http://purl.org/obo/owl/FB#FB_ma cell cell by lineage cell ectodermal cell A cell of the outer of the three germ layers of the embryo. MESH:A.16.254.425.273 http://purl.org/obo/owl/MESH#MESH_A.16.254.425.273 ectoderm cell cell FMA:72549 http://purl.org/obo/owl/FMA#FMA_72549 mesodermal cell A cell of the middle germ layer of the embryo. MESH:A.16.254.425.660 http://purl.org/obo/owl/MESH#MESH_A.16.254.425.660 mesoblast mesoderm cell cell FMA:72554 http://purl.org/obo/owl/FMA#FMA_72554 endodermal cell A cell of the inner of the three germ layers of the embryo. MESH:A.16.254.425.407 http://purl.org/obo/owl/MESH#MESH_A.16.254.425.407 endoderm cell cell FMA:72555 http://purl.org/obo/owl/FMA#FMA_72555 cell by nuclear number A classification of cells by the number of their nuclei. FB:ma http://purl.org/obo/owl/FB#FB_ma GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm cell anucleate cell A cell that lacks a nucleus. FB:ma http://purl.org/obo/owl/FB#FB_ma Non-nucleated cell cell FMA:68647 http://purl.org/obo/owl/FMA#FMA_68647 single nucleate cell A cell with a single nucleus. FB:ma http://purl.org/obo/owl/FB#FB_ma GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm cell binucleate cell cell multinucleate cell A cell with more than one nucleus. FB:ma http://purl.org/obo/owl/FB#FB_ma syncytium syncytial cell syncitium cell lymphoblast Refers to an activated mature lymphocyte phenotype rather than a distinct cell type; consider using 'lymphocyte ; CL:0000542' or one of its children instead. OBSOLETE (was not defined before being made obsolete). cell T lymphoblast Refers to an activated mature T lymphocyte phenotype rather than a distinct cell type; consider using 'T cell ; CL:0000084' or one of its children instead. OBSOLETE (was not defined before being made obsolete). cell B lymphoblast Refers to an activated mature B lymphocyte phenotype rather than a distinct cell type; consider using 'B cell ; CL:0000236' or one of its children instead. OBSOLETE (was not defined before being made obsolete). cell erythrocyte A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm MESH:A.11.118.290 http://purl.org/obo/owl/MESH#MESH_A.11.118.290 red blood cell RBC cell BTO:0000424 http://purl.org/obo/owl/BTO#BTO_0000424 FMA:81100 http://purl.org/obo/owl/FMA#FMA_81100 platelet Platelets are reportedly CCR1-positive, CCR2-negative, CCR3-positive, CCR4-positive, CCR5-negative, CCR6-negative, CCR7-negative, CCR8-negative, CCR9-negative, CCR10-negative, CD16-positive, CD23-positive, CD32-positive, CD40-positive, CD41-positive CD42-positive, CD61-positive, CD62P-positive, CD64-positive, CD89-positive, CD102-positive, CD147-positive (activated platelets), CD154-positive (activated platelets), CD162-positive, CD209, CD282-positive, CD284-positive, CD289-positive, CD181-negative, CD182-negative, CD183-negative, CD184-positive, CLEC2-positive, GPVI-positive, JAMC-positive, PAR1-positive, PAR2-negative, PAR3-positive, PAR4-positive, TSP1-positive, and TXA2R-positive. Platelets can reportedly produce CCL2, CCL3, CCL5, CCL7, CCL17, CD40L, CXCL1, CXCL4, CXCL4L1, CXCL5, CXCL7, CXCL8, CXCL12, EGF, factor V, factor VII, factor XI, factor XIII, bFGF, histamine, IGF-1, IL-1beta, PAI-1, PDGF, plasminogen, protein S, serotonin, TGF-beta, TFPI, VEGF, and vWF. A non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation. GOC:add http://purl.org/obo/owl/GOC#GOC_add GOC:dsd http://purl.org/obo/owl/GOC#GOC_dsd GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm MESH:A.11.118.188 http://purl.org/obo/owl/MESH#MESH_A.11.118.188 MESH:D001792 http://purl.org/obo/owl/MESH#MESH_D001792 PMID:11110672 http://purl.org/obo/owl/PMID#PMID_11110672 PMID:16987572 http://purl.org/obo/owl/PMID#PMID_16987572 PMID:17204662 http://purl.org/obo/owl/PMID#PMID_17204662 PMID:17479180 http://purl.org/obo/owl/PMID#PMID_17479180 PMID:20414831 http://purl.org/obo/owl/PMID#PMID_20414831 enucleate thrombocyte blood platelet anucleate thrombocyte cell BTO:0000132 http://purl.org/obo/owl/BTO#BTO_0000132 FMA:62851 http://purl.org/obo/owl/FMA#FMA_62851 phagocyte Any cell capable of ingesting particulate matter via phagocytosis. GOC:add http://purl.org/obo/owl/GOC#GOC_add ISBN:0721601464 http://purl.org/obo/owl/ISBN#ISBN_0721601464 cell FMA:83806 http://purl.org/obo/owl/FMA#FMA_83806 BTO:0001044 http://purl.org/obo/owl/BTO#BTO_0001044 macrophage Morphology: Diameter 30_M-80 _M, abundant cytoplasm, low N/C ratio, eccentric nucleus. Irregular shape with pseudopods, highly adhesive. Contain vacuoles and phagosomes, may contain azurophilic granules; markers: Mouse & Human: CD68, in most cases CD11b. Mouse: in most cases F4/80+; role or process: immune, antigen presentation, & tissue remodelling; lineage: hematopoietic, myeloid. A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells. GOC:add http://purl.org/obo/owl/GOC#GOC_add GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm GO_REF:0000031 http://purl.org/obo/owl/GO_REF#GO_REF_0000031 PMID:16213494 http://purl.org/obo/owl/PMID#PMID_16213494 PMID:1919437 http://purl.org/obo/owl/PMID#PMID_1919437 URL:http://www.clt.astate.edu/wwilliam/ http://www.clt.astate.edu/wwilliam/ histiocyte cell FMA:63261 http://purl.org/obo/owl/FMA#FMA_63261 FMA:83585 http://purl.org/obo/owl/FMA#FMA_83585 BTO:0000801 http://purl.org/obo/owl/BTO#BTO_0000801 B cell A lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity. GOC:add http://purl.org/obo/owl/GOC#GOC_add GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm GO_REF:0000031 http://purl.org/obo/owl/GO_REF#GO_REF_0000031 ISBN:0781735149 http://purl.org/obo/owl/ISBN#ISBN_0781735149 B lymphocyte B-cell B-lymphocyte cell BTO:0000776 http://purl.org/obo/owl/BTO#BTO_0000776 FMA:62869 http://purl.org/obo/owl/FMA#FMA_62869 keratinizing barrier epithelial cell cell non keratinizing barrier epithelial cell cell brush border epithelial cell cell stratified squamous epithelial cell cell stratified cuboidal epithelial cell cell Merkel cell A modified epidermal cell located in the stratum basale. They are found mostly in areas where sensory perception is acute. Merkel cells are closely associated with an expanded terminal bulb of an afferent myelinated nerve fiber. MESH:A.08.800.550.700.500.425 http://purl.org/obo/owl/MESH#MESH_A.08.800.550.700.500.425 Merkel,s cell cell FMA:70548 http://purl.org/obo/owl/FMA#FMA_70548 glial cell (sensu Vertebrata) A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Form the myelin insulation of nervous pathways, guide neuronal migration during development, and exchange metabolites with neurons. Neuroglia have high-affinity transmitter uptake systems, voltage-dependent and transmitter-gated ion channels, and can release transmitters, but their role in signaling (as in many other functions) is unclear. MESH:A.08.637 http://purl.org/obo/owl/MESH#MESH_A.08.637 cell transitional epithelial cell A cell characteristically found lining hollow organs that are subject to great mechanical change due to contraction and distention; originally thought to represent a transition between stratified squamous and columnar epithelium. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0721662544 http://purl.org/obo/owl/ISBN#ISBN_0721662544 cell FMA:66778 http://purl.org/obo/owl/FMA#FMA_66778 passage cell replaced_by: PO:0000353 Obsolete. Use PO:0000353 from Plant Ontology instead. Cell in exodermis or endodermis that remains thin walled when the associated cells develop thick secondary walls. Has casparian strip in endodermis. ISBN:0471245208 http://purl.org/obo/owl/ISBN#ISBN_0471245208 cell Mauthner neuron cell Rohon-Beard neuron cell microsporocyte replaced_by: PO:0020047 Obsolete. Use PO:0020047 from Plant Ontology instead. A diploid (2n) cell that undergoes meiosis and forms four haploid (1n) microspores; also called microspore mother cell and, in seed plants, pollen mother cell. ISBN:0471245208 http://purl.org/obo/owl/ISBN#ISBN_0471245208 pollen mother cell primary sporogenous cell cell hatching gland cell cell megaspore replaced_by: PO:0020019 Obsolete. Use PO:0020019 from Plant Ontology instead. A haploid (1n) spore developing into a female gametophyte in heterosporous plants. ISBN:0471245208 http://purl.org/obo/owl/ISBN#ISBN_0471245208 cell extramedullary cell cell microspore replaced_by: PO:0020048 Obsolete. Use PO:0020048 from Plant Ontology instead. A haploid (1n) spore developing into a male gametophyte in heterosporous plants; the uninucleate pollen grain in seed plants. ISBN:0471245208 http://purl.org/obo/owl/ISBN#ISBN_0471245208 cell eurydendroid cell cell egg cell replaced_by: PO:0020094 Obsolete. Use PO:0020094 from Plant Ontology instead. The female gamete of plants. TAIR:lr http://purl.org/obo/owl/TAIR#TAIR_lr female gametophyte egg cell cell eukaryotic cell cell uric acid accumulating cell cell Mycetozoan cell cell fiber tracheid replaced_by: PO:0000355 Obsolete. Use PO:0000355 from Plant Ontology instead. A fiber like tracheid in the secondary xylem; commonly thick walled, with pointed ends and bordered pits that have lenticular to slit like apertures. ISBN:0471245208 http://purl.org/obo/owl/ISBN#ISBN_0471245208 cell aggregate cell Differentiating cell composing the aggregate that has acquired adhesive properties. DictyBase:DDB http://purl.org/obo/owl/DictyBase#DictyBase_DDB cell mucilage cell replaced_by: PO:0000373 Obsolete. Use PO:0000373 from Plant Ontology instead. Cell containing mucilages or gums or similar carbohydrate material characterized by the property of swelling in water. ISBN:0471245208 http://purl.org/obo/owl/ISBN#ISBN_0471245208 cell anterior cell cell guard mother cell replaced_by: PO:0000351 Obsolete. Use PO:0000351 from Plant Ontology instead. An epidermal cell that divides to produce the guard cells. ISBN:0471245208 http://purl.org/obo/owl/ISBN#ISBN_0471245208 cell vegetative cell (sensu Mycetozoa) Unicellular haploid myxamoebae that feeds on bacteria and divides by binary fission. DictyBase:DDB http://purl.org/obo/owl/DictyBase#DictyBase_DDB amoeba cell phloem initial replaced_by: PO:0000400 Obsolete. Use PO:0000400 from Plant Ontology instead. A cambial cell on the phloem side of the cambial zone that is the source of one or more cells arising by periclinal divisions and differentiating into phloem elements with or without additional divisions in various planes. ISBN:0471245208 http://purl.org/obo/owl/ISBN#ISBN_0471245208 phloem mother cell cell anterior like cell Cell that has properties of anterior cells (for e.g., accumulate vital dyes in autophagic vesicles) but that is are scattered throughout the rear of the slug. Some but not all these cells express the ecmA gene and/or the ecmB gene. ALCs maintain an amoeboid appearance during culmination. ALCs that express the ecmO promoter have been called pstO/ALC. DictyBase:DDB http://purl.org/obo/owl/DictyBase#DictyBase_DDB ALC cell meristemoid replaced_by: PO:0004011 Obsolete. Use PO:0004011 from Plant Ontology instead. A cell constituting an active locus of meristematic activity in a tissue composed of somewhat older, differentiating cells. ISBN:0471245208 http://purl.org/obo/owl/ISBN#ISBN_0471245208 cell prespore cell Cell that is undergoing differentiation to become a spore. DictyBase:DDB http://purl.org/obo/owl/DictyBase#DictyBase_DDB cell sieve element Obsolete. Consult Plant Ontology instead. The cell in the phloem tissue concerned with mainly longitudinal conduction of food materials. Classified into sieve cell and sieve tube member. ISBN:0471245208 http://purl.org/obo/owl/ISBN#ISBN_0471245208 cell prestalk cell cell subsidiary cell replaced_by: PO:0000284 Obsolete. Use PO:0000284 from Plant Ontology instead. An epidermal cell associated with a stoma and at least morphologically distinguishable from the epidermal cells composing the groundmass of the tissue. ISBN:047124520 http://purl.org/obo/owl/ISBN#ISBN_047124520 cell prestalk A cell Cell expressing the ecmA marker from a promoter region that is proximal to the ATG (ecmAO promoter). They are located at the anterior-most region of the slug. During culmination pstA cells differentiate into pstAB cells. DictyBase:DDB http://purl.org/obo/owl/DictyBase#DictyBase_DDB pstAO pstA cell cambial initial replaced_by PO:0000295 OBSOLETE, use term from Plant Ontology. A cell localized in the vascular cambium or phellogen. Its periclinal division can contribute cells either to the outside or to the inside of the axis; in vascular cambium, classified into fusiform initials (source of axial cells of xylem and phloem) and ray initials (source of the ray cells). ISBN:0471245208 http://purl.org/obo/owl/ISBN#ISBN_0471245208 cell prestalk AB cell Cell that expresses both ecmA and ecmB either simultaneously or sequentially. During culmination pstA differentiate into pstAB cells. DictyBase:DDB http://purl.org/obo/owl/DictyBase#DictyBase_DDB pstAB cell prestalk B cell Cell expressing ecmB but not ecmA. Most pstB cells are located at the very rear of the slug (rearguard region). These cells form part of the basal disc of the fruiting body. If a migratory slug is formed, these cells are left behind. DictyBase:DDB http://purl.org/obo/owl/DictyBase#DictyBase_DDB pstB cell sclerenchyma cell replaced_by: PO:0000077 Obsolete. Use PO:0000077 from Plant Ontology instead. Cell variable in form and size, being more or less thick, often lignified, secondary walls. Belongs to the category of subcells and may or may not be devoid of protoplast at maturity. ISBN:0471245208 http://purl.org/obo/owl/ISBN#ISBN_0471245208 cell prestalk I cell Initial population of prestalk cells that activate the ecmA promoter at the mound stage and that presumably further differentiate into pstA and pstO cells. DictyBase:DDB http://purl.org/obo/owl/DictyBase#DictyBase_DDB cell central cell replaced_by: PO:0020090 Obsolete. Use PO:0020090 from Plant Ontology instead. OBSOLETED, use term from Plant Ontology. A cell containing the two polar nuclei which, after double fertilization, will develop into the endosperm. TAIR:lr http://purl.org/obo/owl/TAIR#TAIR_lr cell prestalk 0 cell Cell that express ecmA at a very low level. Located at the posterior half of the prestalk zone. Expresses ecmA from the distal region of its promoter (ecmO). DictyBase:DDB http://purl.org/obo/owl/DictyBase#DictyBase_DDB cell generative cell replaced_by: PO:0020097 Obsolete. Use PO:0020097 from Plant Ontology instead. The cell that will give rise to the generative nuclei which will participate in fertilization. TAIR:lr http://purl.org/obo/owl/TAIR#TAIR_lr cell pstAB/ALC Anterior-like cell expressing both ecmA and ecmB. DictyBase:DDB http://purl.org/obo/owl/DictyBase#DictyBase_DDB cell trichome replaced_by: PO:0000282 Obsolete. Use PO:0000282 from Plant Ontology instead. An outgrowth from the epidermis. Trichomes vary in size and complexity and include hairs, scales, and other structures and may be glandular. In Arabidopsis, patterning of trichome development is not random but does not appear to be lineage-based like stomata. ISBN:0471245208 http://purl.org/obo/owl/ISBN#ISBN_0471245208 PMID:10938806 http://purl.org/obo/owl/PMID#PMID_10938806 cell pstO/ALC Anterior-like cell that expresses the ecmO promoter and that can move to the position normally occupied by the pstO cells. DictyBase:DDB http://purl.org/obo/owl/DictyBase#DictyBase_DDB cell companion cell replaced_by: PO:0000071 Obsolete. Use PO:0000071 from Plant Ontology instead. A specialized parenchyma cell associated with a sieve-tube member in angiosperm phloem and arising from the same mother cell as the sieve-tube member. ISBN:0879015322 http://purl.org/obo/owl/ISBN#ISBN_0879015322 cell stalk cell Vacuolated cell located at the center of the stalk tube that has a cell wall composed of cellulose and that die upon terminal differentiation. Stalk cells provide structural support for the fruiting body. DictyBase:DDB http://purl.org/obo/owl/DictyBase#DictyBase_DDB cell hyphal cell A cell of a filament of a fungal mycelium. ISBN:08199377X http://purl.org/obo/owl/ISBN#ISBN_08199377X cell eye photoreceptor cell cell synergid replaced_by: PO:0000191 Obsolete. Use PO:0000191 from Plant Ontology instead. A cell in the micropylar end of the embryo sac associated with the egg in the egg apparatus of angiosperms. Plays a vital role in fertilization. ISBN:047125208 http://purl.org/obo/owl/ISBN#ISBN_047125208 cell chemotactic amoeboid cell (sensu Mycetozoa) Starved cell that secretes and responds to chemoattractants (cAMP). DictyBase:DDB http://purl.org/obo/owl/DictyBase#DictyBase_DDB cell xylem fiber cell replaced_by: PO:0000274 Obsolete. Use PO:0000274 from Plant Ontology instead. A fiber of the xylem tissue, Two types are recognized in the secondary xylem: fiber tracheids and libriform fibers. ISBN:0471245208 http://purl.org/obo/owl/ISBN#ISBN_0471245208 cell spore (sensu Mycetozoa) Dormant cell protected by a tri-layer spore coat. The spore has an elliptical shape and is approximately 6-9 microns by 3 microns. DDB_REF:5048 http://purl.org/obo/owl/DDB_REF#DDB_REF_5048 DictyBase:DDB http://purl.org/obo/owl/DictyBase#DictyBase_DDB PMID:4338436 http://purl.org/obo/owl/PMID#PMID_4338436 cell DDANAT:0000414 http://purl.org/obo/owl/DDANAT#DDANAT_0000414 guard cell replaced_by: PO:0000293 Obsolete. Use PO:0000293 from Plant Ontology instead. One of a pair of cells flanking the stomatal pore and causing the opening and closing of the pore by changes in turgor. ISBN:0471245208 http://purl.org/obo/owl/ISBN#ISBN_0471245208 stomatal guard cell cell structural cell A cell whose primary function is to provide structural support, to provide strength and physical integrity to the organism. TAIR:sr http://purl.org/obo/owl/TAIR#TAIR_sr cell sieve cell Obsolete. Consult Plant Ontology instead. A type of sieve element that has relatively undifferentiated sieve areas (with narrow pores), rather uniform in structure on all walls; that is, there are no sieve plates. Typical of gymnosperms and lower vascular plants. ISBN:0471245208 http://purl.org/obo/owl/ISBN#ISBN_0471245208 cell somatotropin secreting cell A peptide hormone secreting cell that produces growth hormone, somatotropin. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm SANBI:mhl http://purl.org/obo/owl/SANBI#SANBI_mhl growth hormone secreting cell somatotrophin secreting cell cell CL:0000471 vegetative cell replaced_by: PO:0020099 Obsolete. Use PO:0020099 from Plant Ontology instead. Cell type formed after the first mitotic division of the microgametophye, The nucleus of this cell migrates to the tip of the pollen tube after germination and disintegrates when the pollen tube penetrates the nucellus. ISBN:0140514031 http://purl.org/obo/owl/ISBN#ISBN_0140514031 TAIR:lr http://purl.org/obo/owl/TAIR#TAIR_lr cell socket cell replaced_by: PO:0000115 Obsolete. Use PO:0000115 from Plant Ontology instead. A cell that surrounds a trichome and provides support for the trichome. PMID:10938806 http://purl.org/obo/owl/PMID#PMID_10938806 cell xylem element replaced_by: PO:0000273 Obsolete. Use PO:0000273 from Plant Ontology instead. A cell composing the xylem. ISBN:0471245208 http://purl.org/obo/owl/ISBN#ISBN_0471245208 cell trichoblast Obsoleted. Use trichoblast from the plant ontology (PO:0000262). OBSOLETED. Commonly used for a cell in root epidermis that gives rise to a root hair. The daughter cell produced by the asymmetric division of a root epidermal cell that gives rise to a root hair. ISBN:0471245208 http://purl.org/obo/owl/ISBN#ISBN_0471245208 cell gamete A mature sexual reproductive cell having a single set of unpaired chromosomes. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0721662544 http://purl.org/obo/owl/ISBN#ISBN_0721662544 haploid nucleated cell haploid germ cell cell FBbt:00005412 http://purl.org/obo/owl/FBbt#FBbt_00005412 FMA:18649 http://purl.org/obo/owl/FMA#FMA_18649 pole cell cell FBbt:00000092 http://purl.org/obo/owl/FBbt#FBbt_00000092 IgM B cell Not a differentiation state per se; consider using 'B cell ; CL:0000236' or one of its children instead. OBSOLETE (was not defined before being made obsolete). cell IgG B cell Not a differentiation state per se, and IgG isotypes vary by species; consider using 'B cell ; CL:0000236' or one of its children instead. OBSOLETE (was not defined before being made obsolete). cell IgA B cell Not a differentiation state per se, and IgA isotypes vary by species. Consider using 'B cell ; CL:0000236' or one of its children instead. OBSOLETE (was not defined before being made obsolete). cell IgE B cell Not a differentiation state per se; consider using 'B cell ; CL:0000236' or one of its children instead. OBSOLETE (was not defined before being made obsolete). cell crystallin accumulating cell lens cell cell FBbt:00004193 http://purl.org/obo/owl/FBbt#FBbt_00004193 tracheal epithelial cell An epithelial cell found in the trachea. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm tracheocyte cell CL:1000474 FMA:74793 http://purl.org/obo/owl/FMA#FMA_74793 FBbt:00005038 http://purl.org/obo/owl/FBbt#FBbt_00005038 metal ion accumulating cell cell copper accumulating cell cuprophilic cell cell iron accumulating cell cell keratin accumulating cell cell keratinocyte Keratinocytes are reportedly CDw210a-negative, CDw210b-positive, CD281Ppositive, CD282-positive, CD285-positive, IL22Ra1-positive, Human keratinocytes are reportedly capable of secreting BD-2, BD-3, hCAP-18, CXCL1, CXCL5, CXCL8, elafin, MMP-3, NGAL, PDGF-A, S100A7, S100A8, and S100A9. Transcription factors: STAT3-positive. An epidermal cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. Successive stages of differentiation of the keratinocytes forming the epidermal layers are basal cell, spinous or prickle cell, and the granular cell. GOC:dsd http://purl.org/obo/owl/GOC#GOC_dsd MESH:A.11.436.397 http://purl.org/obo/owl/MESH#MESH_A.11.436.397 MESH:D015603 http://purl.org/obo/owl/MESH#MESH_D015603 PMID:15582983 http://purl.org/obo/owl/PMID#PMID_15582983 PMID:15749908 http://purl.org/obo/owl/PMID#PMID_15749908 PMID:19727116 http://purl.org/obo/owl/PMID#PMID_19727116 keratinized cell of epidermis malpighian cell cell CL:0002185 FMA:62879 http://purl.org/obo/owl/FMA#FMA_62879 BTO:0000667 http://purl.org/obo/owl/BTO#BTO_0000667 serous secreting cell Columnar glandular cell with irregular nucleus, copious granular endoplasmic reticulum and supranuclear granules. Secretes a watery fluid containing proteins known as serous fluid. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0517223651 http://purl.org/obo/owl/ISBN#ISBN_0517223651 ISBN:0721662544 http://purl.org/obo/owl/ISBN#ISBN_0721662544 serous cell cell BTO:0003687 http://purl.org/obo/owl/BTO#BTO_0003687 FMA:62511 http://purl.org/obo/owl/FMA#FMA_62511 milk secreting cell cell tears secreting cell A cell secreting tears, the fluid secreted by the lacrimal glands. This fluid moistens the conjunctiva and cornea. MESH:A.12.200.882 http://purl.org/obo/owl/MESH#MESH_A.12.200.882 cell ray initial replaced_by: PO:0000082 Obsolete. Use PO:0000082 from Plant Ontology instead. OBSOLETE, use term from Plant Ontology. A meristemic ray cell in the vascular cambium that gives rise to ray cells of the secondary xylem and secondary phloem. ISBN:0471245208 http://purl.org/obo/owl/ISBN#ISBN_0471245208 cell sebum secreting cell A cell secreting sebun, an oily substance secreted by sebaceous glands, composed of keratin, fat, and cellular debris. MESH:A.12.200.702 http://purl.org/obo/owl/MESH#MESH_A.12.200.702 cell sweat secreting cell A cell secreting sweat, the fluid excreted by the sweat glands of mammals. It consists of water containing sodium chloride, phosphate, urea, ammonia, and other waste products. MESH:A.12.200.849 http://purl.org/obo/owl/MESH#MESH_A.12.200.849 cell mucus secreting cell mucous cell cell BTO:0003689 http://purl.org/obo/owl/BTO#BTO_0003689 megasporocyte replaced_by: PO:0000431 Obsolete. Use PO:0000431 from Plant Ontology instead. A diploid (2n) cell that undergoes meiosis and produces four haploid (1n) megaspores; also called megaspore mother cell. ISBN:0471245208 http://purl.org/obo/owl/ISBN#ISBN_0471245208 megaspore mother cell archesporial cell cell seminal fluid secreting cell cell pneumocyte An epithelial cell that lines the peripheral gas exchange region of the lungs of air-breathing vertebrates. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm PMID:20054144 http://purl.org/obo/owl/PMID#PMID_20054144 Alveolar epithelial cell Pneumonocyte cell FMA:62499 http://purl.org/obo/owl/FMA#FMA_62499 BTO:0000395 http://purl.org/obo/owl/BTO#BTO_0000395 lysozyme secreting cell cell metanephric mesenchyme stem cell cell stuff accumulating cell A cell that is specialised to accumulate a particular substance(s). FB:ma http://purl.org/obo/owl/FB#FB_ma cell glycogen accumulating cell cell extracellular matrix secreting cell cell myelin accumulating cell cell oxygen accumulating cell cell collenchymal cell replaced_by: PO:0000075 Obsolete. Use PO:0000075 from Plant Ontology instead. An elongated living cell with unevenly thickened nonlignified primary walls. ISBN:0471245208 http://purl.org/obo/owl/ISBN#ISBN_0471245208 cell tracheid replaced_by: PO:0000301 Obsolete. Use PO:0000301 from Plant Ontology instead. A tracheary element of the xylem that has no perforations, as contrasted with a vessel member. May occur in primary and in secondary xylem. May have any kind of secondary wall thickening found in tracheary elements. ISBN:0471245208 http://purl.org/obo/owl/ISBN#ISBN_0471245208 cell atrichoblast replaced_by: PO:0020090 OBSOLETE, use term from Plant Ontology. A cell formed after asymmetric division of root epidermal cell that does not give rise to a root hair. ISBN:0387987819 http://purl.org/obo/owl/ISBN#ISBN_0387987819 non-hair cell cell neural crest cell A cell of the strip of specialized ectoderm flanking each side of the embryonal neural plate, which after the closure of the neural tube, forms a column of isolated cells along the dorsal aspect of the neural tube. Most of the cranial and all of the spinal sensory ganglion cells arise by differentiation of neural crest cells. MESH:A.16.254.600 http://purl.org/obo/owl/MESH#MESH_A.16.254.600 cell FMA:86667 http://purl.org/obo/owl/FMA#FMA_86667 vegetative cell (sensu Fungi) yeast-form cell FAO:0000032 http://purl.org/obo/owl/FAO#FAO_0000032 BTO:0002307 http://purl.org/obo/owl/BTO#BTO_0002307 mesenchyme condensation cell A mesenchymal cell in embryonic development found in a contracting mass and that gives rise to osteoprogenitors. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm PMID:5025404 http://purl.org/obo/owl/PMID#PMID_5025404 cell adrenal medulla chromaffin cell A cell found within the adrenal medulla that secrete biogenic amine hormones upon stimulation. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm URL:http://www.britannica.com/EBchecked/topic/6405/adrenal-gland http://www.britannica.com/EBchecked/topic/6405/adrenal-gland medullary chromaffin cell of adrenal gland FMA:69262 http://purl.org/obo/owl/FMA#FMA_69262 cell CL:1000422 FMA:69262 http://purl.org/obo/owl/FMA#FMA_69262 neuroblast (sensu Vertebrata) An embryonic cell that develops into a nerve cell or neuron. FMA:70563 http://purl.org/obo/owl/FMA#FMA_70563 cell neuroblast (sensu Nematoda and Protostomia) neuroblast cell glioblast (sensu Vertebrata) An early neural cell developing from the early ependymal cell of the neural tube. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0618947256 http://purl.org/obo/owl/ISBN#ISBN_0618947256 Spongioblast cell FMA:70564 http://purl.org/obo/owl/FMA#FMA_70564 glioblast (sensu Nematoda and Protostomia) cell pigment cell (sensu Nematoda and Protostomia) cell pigment cell (sensu Vertebrata) Any animal cell containing pigment granules. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0721662544 http://purl.org/obo/owl/ISBN#ISBN_0721662544 cell visual pigment cell (sensu Vertebrata) A pigment cell that is capable of detecting light stimulus that is involved in visual perception. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm cell FMA:63846 http://purl.org/obo/owl/FMA#FMA_63846 non-visual cell (sensu Vertebrata) cell dental papilla cell A small mass of condensed mesenchyme in the enamel organ; it differentiates into the dentin and dental pulp. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0721662544 http://purl.org/obo/owl/ISBN#ISBN_0721662544 cell hair follicle dermal papilla cell A specialized mesenchymal cell that resides in the dermal papilla located at the bottom of hair follicles. This cell plays a pivotal roles in hair formation, growth, and cycling. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm PMID:9893172 http://purl.org/obo/owl/PMID#PMID_9893172 cell scleral cell A cell of the sclera of the eye. GOC:add http://purl.org/obo/owl/GOC#GOC_add cell choroidal cell of the eye A cell of the choroid of the eye. GOC:add http://purl.org/obo/owl/GOC#GOC_add cell extraembryonic cell cell amnioserosal cell cell trophoblast cell A cell lining the outside of the blastocyst. After binding to the endometrium, trophoblast cells develop into two distinct layers, an inner layer of mononuclear cytotrophoblast cells and an outer layer of continuous multinuclear cytoplasm, the syncytiotrophoblast cells, which form the early fetal-maternal interface. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm MESH:A.11.936 http://purl.org/obo/owl/MESH#MESH_A.11.936 Trophoblastic cell cell FMA:83028 http://purl.org/obo/owl/FMA#FMA_83028 epiblast cell A cell of the outer layer of a blastula that gives rise to the ectoderm after gastrulation. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0618947256 http://purl.org/obo/owl/ISBN#ISBN_0618947256 cell blastoderm cell An undifferentiated cell produced by early cleavages of the fertilized egg (zygote). MESH:A.11.104 http://purl.org/obo/owl/MESH#MESH_A.11.104 blastomere cell BTO:0001473 http://purl.org/obo/owl/BTO#BTO_0001473 FMA:72551 http://purl.org/obo/owl/FMA#FMA_72551 blastemal cell cell muscle stem cell A multifate stem cell found in skeletal muscle than can differentiate into many different cell types. Distinct cell type from satellite cell. PMID:18282570 http://purl.org/obo/owl/PMID#PMID_18282570 cell FMA:86767 http://purl.org/obo/owl/FMA#FMA_86767 hair matrix stem cell cell stratified epithelial stem cell cell sphincter associated smooth muscle cell cell vascular associated smooth muscle cell A smooth muscle cell assocatiated with the vasculature. GOC:_tfm http://purl.org/obo/owl/GOC#GOC__tfm GOC:dsd http://purl.org/obo/owl/GOC#GOC_dsd vascular smooth muscle cell VSMC cell morula cell A cell of the early embryo at the developmental stage in which the blastomeres, resulting from repeated mitotic divisions of the fertilized ovum (zygote), form a compact cell mass. MESH:A.16.254.270.550 http://purl.org/obo/owl/MESH#MESH_A.16.254.270.550 cell gastrula cell A cell of the embryo in the early stage following the blastula, characterized by morphogenetic cell movements, cell differentiation, and the formation of the three germ layers. MESH:A.16.254.412 http://purl.org/obo/owl/MESH#MESH_A.16.254.412 cell epidermal cell An epithelial cell of the integument (the outer layer of an organism). Flybase:dsj http://purl.org/obo/owl/Flybase#Flybase_dsj MA:ma http://purl.org/obo/owl/MA#MA_ma epithelial cell of skin FMA:62411 http://purl.org/obo/owl/FMA#FMA_62411 cell of epidermis FMA:62411 http://purl.org/obo/owl/FMA#FMA_62411 cell CL:1000396 FMA:62411 http://purl.org/obo/owl/FMA#FMA_62411 BTO:0001470 http://purl.org/obo/owl/BTO#BTO_0001470 axial cell replaced_by: PO:0000081 Obsolete. Use PO:0000081 from Plant Ontology instead. OBSOLETE, use term from the Plant Ontology. A secondary vascular cell that develops from the fusiform cambial initials and oriented with their longest diameter parallel with the main axis of stem or root. These cells make up the axial system, also known as vertical or longitudinal system. ISBN:0471245208 http://purl.org/obo/owl/ISBN#ISBN_0471245208 cell ray cell Obsolete. Consult Plant Ontology. A cell that develops from the ray initial and composes all rays (panels of tissue variable in height and width, formed by the ray initials in the vascular cambium and extending radially in the secondary xylem and secondary phloem) in the secondary vascular tissues. ISBN:0471245208 http://purl.org/obo/owl/ISBN#ISBN_0471245208 cell zygote Diploid cell produced by the fusion of sperm cell nucleus and egg cell. ISBN:0471245208 http://purl.org/obo/owl/ISBN#ISBN_0471245208 cell BTO:0000854 http://purl.org/obo/owl/BTO#BTO_0000854 PO:0000423 http://purl.org/obo/owl/PO#PO_0000423 FMA:72395 http://purl.org/obo/owl/FMA#FMA_72395 sperm cell (sensu Viridiplantae) replaced_by: PO:0000084 Obsolete. Use PO:0000084 from Plant Ontology instead. Male gamete, part of male germ unit. ISBN:0471245208 http://purl.org/obo/owl/ISBN#ISBN_0471245208 pollen germ cell male gametophyte sperm cell gametophyte sperm cell cell sheath cell (sensu Nematoda) glial cell (sensu Nematoda) cell myrosin cell replaced_by: PO:0000352 Obsolete. Use PO:0000352 from Plant Ontology instead. Cell containing glucosinolates ('mustard oil glucosides') and myrosinases, enzymes hydrolyzing the glucosinolates. Occurs in eleven dicotyledon families, the two largest of which are the Brassicaceae and Euphorbiaceae. ISBN:0471245208 http://purl.org/obo/owl/ISBN#ISBN_0471245208 cell transfer cell replaced_by: PO:0000078 Obsolete. Use PO:0000078 from Plant Ontology instead. Parenchyma cell with the wall ingrowth (or invaginations) that increase the surface of the plasmalemma. Appears to be specialized for short-distance transfer of solutes. ISBN:0471245208 http://purl.org/obo/owl/ISBN#ISBN_0471245208 intermediary cell cell protoplast The cell protoplasm after removal of the cell wall. ISBN:08199377X http://purl.org/obo/owl/ISBN#ISBN_08199377X cell tormogen cell An epidermal cell that is part of a cell cluster organ of the insect integument (such as a sensillum) and that secretes a cuticular specialization that forms a socket around the base of a cuticular specialization produced by a trichogen cell. ISBN:978-0801481253 http://purl.org/obo/owl/ISBN#ISBN_978-0801481253 socket cell ISBN:978-0801481253 http://purl.org/obo/owl/ISBN#ISBN_978-0801481253 cell FBbt:00005171 http://purl.org/obo/owl/FBbt#FBbt_00005171 histoblast cell FBbt:00001789 http://purl.org/obo/owl/FBbt#FBbt_00001789 trichogen cell An epidermal cell that is part of a cell cluster organ of the insect integument (such as a sensillum) and that secretes a cuticular specialization, often in the form of a hair, bristle, peg or scale. The base of this specialization is often surrounded by a socket produced by a closely associated tormogen cell. ISBN:978-0801481253 http://purl.org/obo/owl/ISBN#ISBN_978-0801481253 hair cell cell BTO:0004744 http://purl.org/obo/owl/BTO#BTO_0004744 FBbt:00005169 http://purl.org/obo/owl/FBbt#FBbt_00005169 osteoprogenitor cell cell BTO:0002051 http://purl.org/obo/owl/BTO#BTO_0002051 humidity receptor cell cell tracheoblast cell support cell (sensu Nematoda and Protostomia) cell sensory processing neuron cell thecogen cell The support cell that makes the thecogen dendritic cap - a cuticle-like matrix around the tip of the eo-dendrite and which encloses the soma of the eo-neuron. Fbbt:00005173 http://purl.org/obo/owl/Fbbt#Fbbt_00005173 fly sheath cell cell neurosecretory neuron cell FBbt:00005130 http://purl.org/obo/owl/FBbt#FBbt_00005130 scolopidium scolopale cell cell FBbt:00005217 http://purl.org/obo/owl/FBbt#FBbt_00005217 nephrogenic mesenchyme stem cell cell ligament cell cell prohemocyte (sensu Nematoda and Protostomia) cell FBbt:00005062 http://purl.org/obo/owl/FBbt#FBbt_00005062 attachment cell cell hemocyte (sensu Nematoda and Protostomia) cell tendon cell A fibrocyte that is part of a tendon. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm muscle attachment cell tenocyte cell socket cell (sensu Nematoda) cell blood cell (sensu Nematoda and Protostomia) cell podocyte (sensu Diptera) An insect immune cell that develops from plasmatocyte. PMID:12930778 http://purl.org/obo/owl/PMID#PMID_12930778 cell crystal cell cell electrically responsive cell A cell whose function is determined by its response to an electric signal. FB:ma http://purl.org/obo/owl/FB#FB_ma cell plasmatocyte cell FBbt:00001685 http://purl.org/obo/owl/FBbt#FBbt_00001685 procrystal cell cell FBbt:00001689 http://purl.org/obo/owl/FBbt#FBbt_00001689 lamellocyte cell FBbt:00001687 http://purl.org/obo/owl/FBbt#FBbt_00001687 ganglion interneuron cell polygonal cell cell FBbt:00001691 http://purl.org/obo/owl/FBbt#FBbt_00001691 phloem element Obsolete. Consult Plant Ontology instead. OBSOLETED, not defined prior to obsoletion. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm cell pavement cell replaced_by: PO:0000332 Obsolete. Use PO:0000332 from Plant Ontology instead. An epidermal cell with a characteristic convoluted anticlinal cell wall that gives a jigsaw like appearance to the lamina. ISBN:087694289 http://purl.org/obo/owl/ISBN#ISBN_087694289 cell macrophage (sensu Diptera) cell FBbt:00001686 http://purl.org/obo/owl/FBbt#FBbt_00001686 CNS interneuron cell electrically signaling cell A cell that initiates an electrical signal and passes that signal to another cell. FB:ma http://purl.org/obo/owl/FB#FB_ma cell neuroepidermoblast cell FBbt:00005148 http://purl.org/obo/owl/FBbt#FBbt_00005148 CNS short range interneuron cell scolopidial ligament cell cell FBbt:00005221 http://purl.org/obo/owl/FBbt#FBbt_00005221 male gamete cell BTO:0001277 http://purl.org/obo/owl/BTO#BTO_0001277 scolopidial sheath cell cell FBbt:00005219 http://purl.org/obo/owl/FBbt#FBbt_00005219 CNS long range interneuron cell hypodermal cell cell polyploid cell A cell whose nucleus, or nuclei, each contain more than two haploid genomes. FB:ma http://purl.org/obo/owl/FB#FB_ma cell haploid cell A cell whose nucleus contains a single haploid genome. FB:ma http://purl.org/obo/owl/FB#FB_ma GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm cell cell by ploidy A classification of cells by the number of haploid genome equivalents of their nucleus or nuclei. FB:ma http://purl.org/obo/owl/FB#FB_ma GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm cell diploid cell A cell whose nucleus has two haploid genomes. FB:ma http://purl.org/obo/owl/FB#FB_ma cell polytene cell cell endopolyploid cell cell arcade cell An epithelial cell found in C. elegans that firmly hold the outer body wall and the lips to the inner cylinder of the pharynx in a manner that keeps these organs from breaking apart, while still giving each organ freedom of movement during feeding. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm URL:http://www.wormatlas.org/ver1/handbook/hypodermis/hypsupportother.htm#arcadecells http://www.wormatlas.org/ver1/handbook/hypodermis/hypsupportother.htm#arcadecells cell seam cell cell BTO:0003039 http://purl.org/obo/owl/BTO#BTO_0003039 syncytial epithelial cell cell coelomocyte A free floating cell, including amebocytes and eleocytes, in the coelom of certain animals, especially annelids. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0721662544 http://purl.org/obo/owl/ISBN#ISBN_0721662544 cell BTO:0002856 http://purl.org/obo/owl/BTO#BTO_0002856 mitogenic signaling cell A cell whose primary function is to cause growth by stimulating cell division in its immediate cellular environment. FB:ma http://purl.org/obo/owl/FB#FB_ma cell tip cell cell excretory cell A cell involved in the elimination of metabolic and foreign toxins, and in maintaining the ionic, acid-base and water balance of biological fluids. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm PMID:19783135 http://purl.org/obo/owl/PMID#PMID_19783135 cell pore cell Forms the terminal part of the cuticle-lined excretory duct of C. elegans. JB:jb http://purl.org/obo/owl/JB#JB_jb cell scaffold cell cell GLR cell A scaffolding cell type found in C. elegans, this cell plays a supportive role to the muscle arms. May also have an endocrine role. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm URL:http://wormatlas.psc.edu/hermaphrodite/muscleGLR/mainframe.htm http://wormatlas.psc.edu/hermaphrodite/muscleGLR/mainframe.htm cell yolk cell cell imaginal disc cell cell xanthophore A pigment cell derived from the neural crest. Contains cartenoid pigments in structures called pterinosomes or xanthosomes. This gives an appearance ranging from a golden yellow to orange and red. SANBI:mhl http://purl.org/obo/owl/SANBI#SANBI_mhl cell iridophore A pigment cell derived from the neural crest. The cell contains flat light-reflecting platelets, probably of guanine, in stacks called reflecting platets or iridisomes. The color-generating components produce a silver, gold, or iridescent color. SANBI:mhl http://purl.org/obo/owl/SANBI#SANBI_mhl cell reticular cell Large, stellate fibroblast found along the network of collagen fibers of the reticulum of the spleen; synthesize the matrix components of the reticulum. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0517223651 http://purl.org/obo/owl/ISBN#ISBN_0517223651 reticulum cell cell FMA:62877 http://purl.org/obo/owl/FMA#FMA_62877 functional megaspore replaced_by: PO:0000244 Obsolete. Use PO:0000244 from Plant Ontology instead. In monosporic and bisporic megasporogenesis: the megaspore(s) that will undergo megagametogenesis. TAIR:lr http://purl.org/obo/owl/TAIR#TAIR_lr cell eccrine cell A secretory cell that discharges its product without loss of cytoplasm. ISBN:0198547684 http://purl.org/obo/owl/ISBN#ISBN_0198547684 cell alkali secreting cell cell vaginal lubricant secreting cell cell gonadtroph A rounded cell that is usually situated next to sinusoids; secretes follicular stimulating hormone (FSH) and luteinizing hormone (LH). GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0517223651 http://purl.org/obo/owl/ISBN#ISBN_0517223651 http:63.198.234.228/OpenFMA/Gonadotroph.html http://purl.org/obo/owl/http#http_63.198.234.228/OpenFMA/Gonadotroph.html Gonadotrope delta basophil gonadotroph Gonadotrope cell Pituitary delta cell follicle stimulating hormone secreting cell cell BTO:0002482 http://purl.org/obo/owl/BTO#BTO_0002482 FMA:83100 http://purl.org/obo/owl/FMA#FMA_83100 luteinizing hormone secreting cell A peptide hormone secreting cell pituitary that produces luteinizing hormone. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm cell prolactin secreting cell A peptide hormone cell that secretes prolactin. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm SANBI:mhl http://purl.org/obo/owl/SANBI#SANBI_mhl cell melanocyte stimulating hormone secreting cell A cell of the intermediate pituitary that produces melanocyte stimulating hormone. SANBI:mhl http://purl.org/obo/owl/SANBI#SANBI_mhl melanotrope melanotroph cell BTO:0002277 http://purl.org/obo/owl/BTO#BTO_0002277 follicle stem cell cell FBbt:00004903 http://purl.org/obo/owl/FBbt#FBbt_00004903 follicular dendritic cell Due to its unique lineage and distinct function, this is not a type of dendritic cell; CL:0000451. A cell with extensive dendritic processes found in the B cell areas (primary follicles and germinal centers) of lymphoid tissue. They are unrelated to the dendritic cell associated with T cells. Follicular dendritic cells have Fc receptors and C3b receptors, but unlike other dendritic cells, they do not process or present antigen in a way that allows recognition by T cells. Instead, they hold antigen in the form of immune complexes on their surfaces for long periods and can present antigen to B cells during an immune response. ISBN:127520252 http://purl.org/obo/owl/ISBN#ISBN_127520252 cell BTO:0004267 http://purl.org/obo/owl/BTO#BTO_0004267 FMA:83037 http://purl.org/obo/owl/FMA#FMA_83037 calcitonin secreting cell cell obliquely striated muscle cell cell apoptosis fated cell cell chief cell of parathyroid gland An epithelial cell of the parathyroid gland that is arranged in wide, irregular interconnecting columns; responsible for the synthesis and secretion of parathyroid hormone. FMA:69078 http://purl.org/obo/owl/FMA#FMA_69078 GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0517223651 http://purl.org/obo/owl/ISBN#ISBN_0517223651 parathyroid hormone secreting cell Principal cell of parathyroid gland Parathyroid gland chief cell Parathyroid chief cell cell FMA:69078 http://purl.org/obo/owl/FMA#FMA_69078 BTO:0004712 http://purl.org/obo/owl/BTO#BTO_0004712 carbohydrate secreting cell cell white fat cell Fat cells with light coloration and few mitochondria. They contain a scant ring of cytoplasm surrounding a single large lipid droplet or vacuole. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm MESH:A11.329.114.500 http://purl.org/obo/owl/MESH#MESH_A11.329.114.500 White fat cell white adipocyte White adipose cell cell FMA:83434 http://purl.org/obo/owl/FMA#FMA_83434 brown fat cell A cell from the thermogenic form of adipose tissue found in newborns of many species, including humans, and in hibernating mammals. Brown fat is capable of rapid liberation of energy and seems to be important in the maintenance of body temperature immediately after birth and upon waking from hibernation. MESH:A.10.165.114.322 http://purl.org/obo/owl/MESH#MESH_A.10.165.114.322 Brown adipocyte Brown adipose cell cell FMA:83435 http://purl.org/obo/owl/FMA#FMA_83435 dendritic cell A cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. These cells are lineage negative (CD3-negative, CD19-negative, CD34-negative, and CD56-negative). GOC:add http://purl.org/obo/owl/GOC#GOC_add ISBN:0781735149 http://purl.org/obo/owl/ISBN#ISBN_0781735149 veiled cell interdigitating cell cell BTO:0002042 http://purl.org/obo/owl/BTO#BTO_0002042 FMA:83036 http://purl.org/obo/owl/FMA#FMA_83036 thyroid hormone secreting cell cell Langerhans cell Originally described in the dendritic cell ontology (DC_CL:0000021 )(PMID: 19243617). These cells are also CD1a-high, CD14-negative, CD207-positive (langerin), CD324-positive (E-cadherin), and DCIR-positive. They reside in the epidermis. Langerhans cell is a conventional dendritic cell that has plasma membrane part CD207. A Langerhans cell is a stellate dendritic cell of myeloid origin, that appears clear on light microscopy and has a dark-staining, indented nucleus and characteristic inclusions (Birbeck granules) in the cytoplasm; Langerhans cells are found principally in the stratum spinosum of the epidermis, but they also occur in other stratified epithelia and have been identified in the lung, lymph nodes, spleen, and thymus. GOC:add http://purl.org/obo/owl/GOC#GOC_add GOC:amm http://purl.org/obo/owl/GOC#GOC_amm GO_REF:0000031 http://purl.org/obo/owl/GO_REF#GO_REF_0000031 ISBN:0721601464 http://purl.org/obo/owl/ISBN#ISBN_0721601464 ISBN:0781735149 http://purl.org/obo/owl/ISBN#ISBN_0781735149 PMCID:PMC2346585 http://purl.org/obo/owl/PMCID#PMCID_PMC2346585 PMID:17850486 http://purl.org/obo/owl/PMID#PMID_17850486 LC Langerhans' cell cell FMA:63072 http://purl.org/obo/owl/FMA#FMA_63072 BTO:0000705 http://purl.org/obo/owl/BTO#BTO_0000705 epinephrin secreting cell A cell capable of producting Epinephrine. Epiniphrine is synthesized from norepiniphrine by the actions of the phenylethanolamine N-methyltransferase enzyme, which is expressed in the adrenal glands, androgenic neurons, and in other cell types. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm PMID:12438093 http://purl.org/obo/owl/PMID#PMID_12438093 adrenaline secreting cell cell starch sheath cell replaced_by: PO:0004531 Obsolete. Use PO:0004531 from Plant Ontology instead. A cell characterized by conspicuous and rather stable accumulation of starch. ISBN:044174520 http://purl.org/obo/owl/ISBN#ISBN_044174520 cell mineralocorticoid secreting cell cell biogenic amine secreting cell cell serotonin secreting cell A cell type that secretes 5-Hydroxytryptamine (serotonin). GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm PMID:19630576 http://purl.org/obo/owl/PMID#PMID_19630576 5-HT secreting cell 5-Hydroxytryptamine secreting cell cell norepinephrin secreting cell A cell capable of producting norepiniphrine. Norepiniphrine is a catecholamine with multiple roles including as a hormone and a neurotransmitter. In addition, epiniphrine is synthesized from norepiniphrine by the actions of the phenylethanolamine N-methyltransferase enzyme. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:068340007X http://purl.org/obo/owl/ISBN#ISBN_068340007X noradrenalin secreting cell cell glucocorticoid secreting cell cell adepithelial cell cell FBbt:00003219 http://purl.org/obo/owl/FBbt#FBbt_00003219 epidermal cell (sensu arthropoda) While insect epidermis is generally columnar/cuboidal, there are certainly well studied cases where it is not (e.g.- Rhodnius prolixus when starved). So it would be safer to add this as a differentium for particular species where this is known. -DSJ An epidermal cell that secretes chitinous cuticle from its apical side. FlyBase:ds http://purl.org/obo/owl/FlyBase#FlyBase_ds ISBN:ISBN:978-0801481253 http://purl.org/obo/owl/ISBN#ISBN_ISBN:978-0801481253 cell epidermoblast An epidermal progenitor cell that arises from neuroectoderm and in turn gives rise to the epidermal sheath of ventral and cephalic regions. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm PMID:7576311 http://purl.org/obo/owl/PMID#PMID_7576311 cell FBbt:00004994 http://purl.org/obo/owl/FBbt#FBbt_00004994 cardioblast (sensu Arthropoda) cell FBbt:00001666 http://purl.org/obo/owl/FBbt#FBbt_00001666 adrenocorticotropic hormone secreting cell A peptide hormone secreting cell that produces adrenocorticotropin, or corticotropin. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm SANBI:mhl http://purl.org/obo/owl/SANBI#SANBI_mhl corticotropin hormone secreting cell adrenocorticotrophic hormone secreting cell corticotrophin hormone secreting cell cell CL:0000640 neuroglioblast cell FBbt:00005147 http://purl.org/obo/owl/FBbt#FBbt_00005147 ganglion mother cell cell FBbt:00005149 http://purl.org/obo/owl/FBbt#FBbt_00005149 digestive enzyme secreting cell cell chlorenchyma cell replaced_by: PO:0000076 Obsolete. Use PO:0000076 from Plant Ontology instead. OBSOLETE, use term from Plant Ontology. Parenchyma cells containing chloroplasts; a component of leaf mesophyll and other green parenchyma tissue. ISBN:0471245208 http://purl.org/obo/owl/ISBN#ISBN_0471245208 cell defensive cell A cell whose primary function is to protect the organism. JB:jb http://purl.org/obo/owl/JB#JB_jb cell pericardial cell Cell which forms the outer layer of the dorsal vessel within the abdomen of the fly larvae. These cells sequester macromolecules from the hemolymph. FBbt:00003184 http://purl.org/obo/owl/FBbt#FBbt_00003184 GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm PMID:19783135 http://purl.org/obo/owl/PMID#PMID_19783135 cell FBbt:00003184 http://purl.org/obo/owl/FBbt#FBbt_00003184 degenerate megaspore replaced_by: PO:0000245 Obsolete. Use PO:0000245 from Plant Ontology instead. In monosporic and bisporic megasporogenesis: the megaspore(s) that do not participate in megagametogenesis. TAIR:lr http://purl.org/obo/owl/TAIR#TAIR_lr cell thyrotroph A basophil cell of the anterior pituitary that produces thyroid stimulating hormone, thyrotrophin. This cell type is elongated, polygonal and lie in clusters towards the adenohypophyseal center. ISBN:0517223651 http://purl.org/obo/owl/ISBN#ISBN_0517223651 SANBI:mhl http://purl.org/obo/owl/SANBI#SANBI_mhl beta-basophil thyrotrope thyroid stimulating hormone secreting cell cell FMA:83099 http://purl.org/obo/owl/FMA#FMA_83099 follicle cell cell FBbt:00004904 http://purl.org/obo/owl/FBbt#FBbt_00004904 oxytocin stimulating hormone secreting cell A peptide hormone secreting cell that secretes oxytocin stimulating hormone GO:tfm http://purl.org/obo/owl/GO#GO_tfm cell vasopressin stimulating hormone secreting cell A peptide hormone secreting cell that secretes vasopressin stimulating hormone GO:tfm http://purl.org/obo/owl/GO#GO_tfm cell secretin stimulating hormone secreting cell A peptide hormone secreting cell that secretes secretin stimulating hormone GO:tfm http://purl.org/obo/owl/GO#GO_tfm cell cholecystokin stimulating hormone secreting cell A peptide hormone secreting cell that secretes cholecystokin stimulating hormone GO:tfm http://purl.org/obo/owl/GO#GO_tfm cell juvenile hormone secreting cell An endocrine cell that secretes juvenile hormone. GO:tfm http://purl.org/obo/owl/GO#GO_tfm cell bombesin stimulating hormone secreting cell A peptide hormone secreting cell that secretes cholecystokin stimulating hormone GO:tfm http://purl.org/obo/owl/GO#GO_tfm cell connective tissue type mast cell They are CD88-positive. The cytoplasmic granules contain high levels of histamine and heparin (mouse) or major neutral proteases, tryptase, chymase, carboxypeptidase A, and cathepsin G (humans). Reportedly, they cannot produce leukotrienes (LTC4) and IL-4. They are reportedly very heterogeneous depending upon location and can convert to the MC(T) phenotype. Mast cell subtype whose granules contain both the serine proteases tryptase and chymase. These cells are primarily found in connective tissue, such as the peritoneal cavity, skin, and intestinal submucosa. Their development is T-cell independent. GOC:add http://purl.org/obo/owl/GOC#GOC_add GOC:dsd http://purl.org/obo/owl/GOC#GOC_dsd GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm PMID:19923473 http://purl.org/obo/owl/PMID#PMID_19923473 PMID:9354811 http://purl.org/obo/owl/PMID#PMID_9354811 MC(TC) MCTC TC mast cells cell mucosal type mast cell They are CD88-negative. The cytoplasmic granules contain low levels of histamine and high levels of chondroitin sulfate (mouse) or major neutral proteases and tryptase (humans). Additionally, they can produce leukotrienes (LTC4), IL-5, IL-6, and low levels of IL-4. They are reportedly very heterogeneous depending upon location and can convert to the MC(T) phenotype. Mast cell subtype that contains only the serine protease trypase in its granules. These cells are primarily found in mucosal tissue, such as intestinal mucosa and alveoli. They depend upon T-cells for development of phenotype. GOC:add http://purl.org/obo/owl/GOC#GOC_add GOC:dsd http://purl.org/obo/owl/GOC#GOC_dsd PMID:19923473 http://purl.org/obo/owl/PMID#PMID_19923473 PMID:9354811 http://purl.org/obo/owl/PMID#PMID_9354811 MC(T) MCT T mast cells cell garland cell A large binucleate cell that forms a 'garland' around the anterior end of the proventriculus (cardia) at its junction with the esophagus in both adults and larvae flies. Each cell is surrounded by a basement membrane and there are numerous micro-invaginations (lacunae) extending from the surface into the cytoplasm. At the mouth of each lacuna is a doubled filament forming a specialised filtration system (diaphragm). The filtrate is endocytosed from the lacunae. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm PMID:19783135 http://purl.org/obo/owl/PMID#PMID_19783135 fbbt:00005059 http://purl.org/obo/owl/fbbt#fbbt_00005059 cell FBbt:00005059 http://purl.org/obo/owl/FBbt#FBbt_00005059 BTO:0004596 http://purl.org/obo/owl/BTO#BTO_0004596 oenocyte A large secretory cell found in clusters underlying the epidermis of the abdominal segments of larval abdominal segments. GOC:bf http://purl.org/obo/owl/GOC#GOC_bf PMID:11171397 http://purl.org/obo/owl/PMID#PMID_11171397 cell FBbt:00004995 http://purl.org/obo/owl/FBbt#FBbt_00004995 visible light photoreceptor cell A photoreceptor cell that detects visible light. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm cell scotopic photoreceptor cell cell photopic photoreceptor cell cell cytotoxic T cell This term had an incorrect definition and was overly broad. Consider using 'cytotoxic T cell ; CL:0000910' (in most cases) or another lymphocyte cell type if cytotoxicity is shown to be part of the cell's phenotype in a particular experimental situation. OBSOLETE: A cell responsible for spontaneous cytotoxicity of a variety of tumor cells without prior immunization. These natural killer cells are found in non-immune humans and experimental animals and are thought by some to be the same as killer cells (killing by antibody-dependent cell cytotoxicity), but they can also kill in the absence of antibody. cell CD4-positive helper T cell A CD4-positive, alpha-beta T cell that cooperates with other lymphocytes via direct contact or cytokine release to initiate a variety of immune functions. GOC:add http://purl.org/obo/owl/GOC#GOC_add GOC:pam http://purl.org/obo/owl/GOC#GOC_pam GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm GO_REF:0000031 http://purl.org/obo/owl/GO_REF#GO_REF_0000031 ISBN:0781735149 http://purl.org/obo/owl/ISBN#ISBN_0781735149 MESH:A.11.118.637.555.567.569.200.400 http://purl.org/obo/owl/MESH#MESH_A.11.118.637.555.567.569.200.400 CD4-positive helper T lymphocyte CD4-positive T-helper cell CD4-positive helper T-lymphocyte CD4-positive helper T-cell cell FMA:70572 http://purl.org/obo/owl/FMA#FMA_70572 regulatory T cell This term was defined too narrowly; consider using the term 'regulatory T cell ; CL:0000815' instead. OBSOLETE: Subpopulation of CD4+ cells which induce CD8+ suppressor T cells to suppress antibody production by B cells. They also stimulate other cellular immune responses. cell UV sensitive photoreceptor cell A photoreceptor cell that detects ultraviolet light. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm cell blue sensitive photoreceptor cell A photoreceptor cell that is sensitive to blue light. GO:tfm http://purl.org/obo/owl/GO#GO_tfm cell green sensitive photoreceptor cell A photoreceptor cell that is sensitive to green light. GO:tfm http://purl.org/obo/owl/GO#GO_tfm cell red sensitive photoreceptor cell A photoreceptor cell that is sensitive to red light. GO:tfm http://purl.org/obo/owl/GO#GO_tfm cell inhibitory interneuron An interneuron (also called relay neuron, association neuron or local circuit neuron) is a multipolar neuron which connects afferent neurons and efferent neurons in neural pathways. Like motor neurons, interneuron cell bodies are always located in the central nervous system (CNS). GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm URL:http://en.wikipedia.org/wiki/Interneuron http://en.wikipedia.org/wiki/Interneuron cell FMA:84776 http://purl.org/obo/owl/FMA#FMA_84776 stromal cell A connective tissue cell of an organ found in the loose connective tissue. These are most often associated with the uterine mucosa and the ovary as well as the hematopoietic system and elsewhere. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm MESH:A.11.329.830 http://purl.org/obo/owl/MESH#MESH_A.11.329.830 cell BTO:0002064 http://purl.org/obo/owl/BTO#BTO_0002064 FMA:83624 http://purl.org/obo/owl/FMA#FMA_83624 follicular epithelial cell cell granulosa cell A supporting cell for the developing female gamete in the ovary of mammals. They develop from the coelomic epithelial cells of the gonadal ridge. Granulosa cells form a single layer around the mammalian oocyte in the primordial ovarian follicle and advance to form a multilayered cumulus oophorus surrounding the ovum in the Graafian follicle. The major functions of granulosa cells include the production of steroids and LH receptors. MESH:A.05.360.319.114.630.535.200 http://purl.org/obo/owl/MESH#MESH_A.05.360.319.114.630.535.200 granulosa cell of ovary cell FMA:18718 http://purl.org/obo/owl/FMA#FMA_18718 BTO:0000542 http://purl.org/obo/owl/BTO#BTO_0000542 type D enteroendocrine cell A cell found throughout the gastrointestinal tract and in the pancreas. They secrete somatostatin in both an endocrine and paracrine manner. Somatostatin inhibits gastrin, cholecystokinin, insulin, glucagon, pancreatic enzymes, and gastric hydrochloric acid. A variety of substances which inhibit gastric acid secretion (vasoactive intestinal peptide, calcitonin gene-related peptide, cholecystokinin, beta-adrenergic agonists, and gastric inhibitory peptide) are thought to act by releasing somatostatin. MESH:A.03.492.766.440.175 http://purl.org/obo/owl/MESH#MESH_A.03.492.766.440.175 D cell cell FMA:62935 http://purl.org/obo/owl/FMA#FMA_62935 theca cell A flattened stroma cell forming a sheath or theca outside the basal lamina lining the mature ovarian follicle. Thecal interstitial or stromal cells are steroidogenic, and produce primarily androgens which serve as precusors of estrogens in the granulosa cells. MESH:A.05.360.319.114.630.535.400 http://purl.org/obo/owl/MESH#MESH_A.05.360.319.114.630.535.400 cell FMA:18690 http://purl.org/obo/owl/FMA#FMA_18690 BTO:0002850 http://purl.org/obo/owl/BTO#BTO_0002850 enterochromaffin-like cell Consider enterochromaffin cell (CL:0002065). For several years this cell type was "enterochromaffin cell" despite a MESH dbxref and a free text definition that clearly meant enterochromaffin-like cell. A enteroendocrine cell part of the glands of the gastric mucosa. They produce histamine and peptides such as chromogranins. This cell type respond to gastrin by releasing histamine which acts as a paracrine stimulator of the release of hydrochloric acid from the gastric parietal cells. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm MESH:A.06.224.365 http://purl.org/obo/owl/MESH#MESH_A.06.224.365 ECL cell BTO:0002692 http://purl.org/obo/owl/BTO#BTO_0002692 substance P secreting cell A peptide hormone secreting cell that secretes substance P. GO:tfm http://purl.org/obo/owl/GO#GO_tfm cell enkephalin secreting cell An endorphine cell that secretes enkephalin. GO:tfm http://purl.org/obo/owl/GO#GO_tfm cell endorphin secreting cell A peptide hormone secreting cell that secretes endorphin. GO:tfm http://purl.org/obo/owl/GO#GO_tfm cell type G enteroendocrine cell An endocrine cell found in the pyloric gland mucosa (antral mucosa) of the stomach of mammals and responsible for the secretion of gastrin and enkephalin. Most abundant in pyloric antrum, pyramidal in form with a narrow apex bearing long microvilli. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0517223651 http://purl.org/obo/owl/ISBN#ISBN_0517223651 MESH:A.03.492.766.440.300 http://purl.org/obo/owl/MESH#MESH_A.03.492.766.440.300 G cell cell FMA:67609 http://purl.org/obo/owl/FMA#FMA_67609 BTO:0004108 http://purl.org/obo/owl/BTO#BTO_0004108 gastrin secreting cell A peptide hormone secreting cell that secretes gastrin. GO:tfm http://purl.org/obo/owl/GO#GO_tfm cell paneth cell An epithelial cell found in the basal part of the intestinal glands (crypts of Lieberkuhn) including the appendix. Paneth cells synthesize and secrete lysozyme and cryptdins. Numerous in the deeper parts of the intestinal crypts, particularly in the duodenum, rich in zinc, contain large acidophilic granules, with irregular apical microvilli and prominent membrane-bound vacuoles containing matrix. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0517223651 http://purl.org/obo/owl/ISBN#ISBN_0517223651 MESH:A.03.492.411.369.700 http://purl.org/obo/owl/MESH#MESH_A.03.492.411.369.700 cell BTO:0000993 http://purl.org/obo/owl/BTO#BTO_0000993 FMA:62897 http://purl.org/obo/owl/FMA#FMA_62897 androgen binding protein secreting cell A peptide hormone secreting cell that secretes androgen binding protein. GO:tfm http://purl.org/obo/owl/GO#GO_tfm cell paracrine cell A paracrine cell is a secretory cell that secretes an agonist into intercellular spaces in which it diffuses to a target cell other than that which produced it. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0198529171 http://purl.org/obo/owl/ISBN#ISBN_0198529171 cell cardiac muscle myoblast A precursor cell destined to differentiate into cardiac muscle cell. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm MESH:A.11.635.470 http://purl.org/obo/owl/MESH#MESH_A.11.635.470 cell CL:0000714 FMA:84797 http://purl.org/obo/owl/FMA#FMA_84797 smooth muscle myoblast A precursor cell destined to differentiate into smooth muscle myocytes. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm MESH:A.11.635.510 http://purl.org/obo/owl/MESH#MESH_A.11.635.510 MESH:D032390 http://purl.org/obo/owl/MESH#MESH_D032390 satellite cell myoblast, smooth muscle MESH:D032390 http://purl.org/obo/owl/MESH#MESH_D032390 cell FMA:84798 http://purl.org/obo/owl/FMA#FMA_84798 skeletal muscle myoblast A myoblast that differentiates into skeletal muscle fibers. SANBI:mhl http://purl.org/obo/owl/SANBI#SANBI_mhl skeletal myoblast cell FMA:84799 http://purl.org/obo/owl/FMA#FMA_84799 perineuronal satellite cell A non-neuronal cell that surrounds the neuronal cell bodies of the ganglia. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm MESH:A.08.340.685 http://purl.org/obo/owl/MESH#MESH_A.08.340.685 Satellite oligodendrocyte Perineuronal satellite oligodendroglial cell perineural satellite cell cell FMA:54550 http://purl.org/obo/owl/FMA#FMA_54550 macrophage derived foam cell A type of foam cell derived from a macrophage containing lipids in small vacuoles and typically seen in atherolosclerotic lesions, as well as other conditions. GOC:add http://purl.org/obo/owl/GOC#GOC_add PMID:20213546 http://purl.org/obo/owl/PMID#PMID_20213546 cell phagocyte (sensu Vertebrata) A phagocyte in vertebrates that is able to phagocytosis. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm cell phagocyte (sensu Nematoda and Protostomia) A phagocyte from organisms in the Nematoda or Protostomia clades. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm cell prokaryotic cell cell fungal cell cell spore The reproductive structure of bacteria, fungi and cryptograms. ISBN:08199377X http://purl.org/obo/owl/ISBN#ISBN_08199377X cell mononuclear cytotrophoblast cell A cell from the inner layer of the trophoblast of the early mammalian embryo that gives rise to the outer surface and villi of the chorion. Mononuclear crytoblasts fuse to give rise to a multinuclear cytotrophoblast. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0323052908 http://purl.org/obo/owl/ISBN#ISBN_0323052908 Langhans' cell cell FMA:83042 http://purl.org/obo/owl/FMA#FMA_83042 spheroplast A cell, usually of bacteria or yeast, which has partially lost its cell wall. MESH:A.11.868 http://purl.org/obo/owl/MESH#MESH_A.11.868 sphaeroplast cell syncytiotrophoblast cell A cell from the outer syncytial layer of the trophoblast of an early mammalian embryo. It It secretes hCG in order to maintain progesterone secretion and sustain a pregnancy. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0323052908 http://purl.org/obo/owl/ISBN#ISBN_0323052908 syntrophoblast plasmidotrophoblast syncytial trophoblast cell FMA:83043 http://purl.org/obo/owl/FMA#FMA_83043 afferent neuron A neuron which conveys sensory information centrally from the periphery. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm MESH:A.08.663.650 http://purl.org/obo/owl/MESH#MESH_A.08.663.650 input neuron cell FMA:87653 http://purl.org/obo/owl/FMA#FMA_87653 efferent neuron A neuron which sends impulses peripherally to activate muscles or secretory cells. MESH:A.08.663.655 http://purl.org/obo/owl/MESH#MESH_A.08.663.655 output neuron cell nitrergic neuron A nerve cell where transmission is mediated by nitric oxide. MESH:A.08.663.748 http://purl.org/obo/owl/MESH#MESH_A.08.663.748 cell FMA:84792 http://purl.org/obo/owl/FMA#FMA_84792 pigmented epithelial cell cell primary neuron cell primary sensory neuron cell CAP motoneuron cell primary motor neuron cell FMA:83619 http://purl.org/obo/owl/FMA#FMA_83619 primary interneuron cell secondary neuron cell secondary motor neuron cell FMA:83620 http://purl.org/obo/owl/FMA#FMA_83620 antipodal cell replaced_by: PO:0020093 Obsolete. Use PO:0020093 from Plant Ontology instead. OBSOLETE, use term from plant ontology. A cell located at the chalazal end of the mature embryo sac in angiosperms. ISBN:047125208 http://purl.org/obo/owl/ISBN#ISBN_047125208 cell epidermal initial replaced_by: PO:0000349 Obsolete. Use PO:0000349 from Plant Ontology instead. A relatively unspecialized cell that will give rise to specialized cell types of the epidermis. TAIR:lr http://purl.org/obo/owl/TAIR#TAIR_lr cell idioblast A cell in a tissue that markedly differs in form, size, or contents from other cells in the same tissue. ISBN:0471245208 http://purl.org/obo/owl/ISBN#ISBN_0471245208 cell neuron These cells are also reportedly CD4-negative and CD200-positive. They are also capable of producing CD40L and IFN-gamma. The basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system. MESH:A.08.663 http://purl.org/obo/owl/MESH#MESH_A.08.663 MESH:D009474 http://purl.org/obo/owl/MESH#MESH_D009474 nerve cell cell FBbt:00005106 http://purl.org/obo/owl/FBbt#FBbt_00005106 FMA:54527 http://purl.org/obo/owl/FMA#FMA_54527 BTO:0000938 http://purl.org/obo/owl/BTO#BTO_0000938 melanoblast Derived from UBERON:0002342 neural crest. A cell that originates from the neural crest and differentiates into a pigment cell. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm SANBI:mhl http://purl.org/obo/owl/SANBI#SANBI_mhl cell BTO:0003217 http://purl.org/obo/owl/BTO#BTO_0003217 FMA:83377 http://purl.org/obo/owl/FMA#FMA_83377 lymphocyte A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin. GOC:add http://purl.org/obo/owl/GOC#GOC_add ISBN:0683073696 http://purl.org/obo/owl/ISBN#ISBN_0683073696 ISBN:0781735149 http://purl.org/obo/owl/ISBN#ISBN_0781735149 cell FMA:62863 http://purl.org/obo/owl/FMA#FMA_62863 BTO:0000775 http://purl.org/obo/owl/BTO#BTO_0000775 sieve tube member replaced_by: PO:0000289 Obsolete. Use PO:0000289 from Plant Ontology instead. One of the series of cellular components of a sieve tube. It shows a more or less pronounced differentiation between sieve plates (wide pores) and lateral sieve areas (narrow pores). Also sieve tube element and the obsolete sieve tube segment. ISBN:0471245208 http://purl.org/obo/owl/ISBN#ISBN_0471245208 sieve tube element cell slowly adapting mechanoreceptor cell cell T-helper 1 cell A CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma. GOC:add http://purl.org/obo/owl/GOC#GOC_add GOC:pam http://purl.org/obo/owl/GOC#GOC_pam GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm GO_REF:0000031 http://purl.org/obo/owl/GO_REF#GO_REF_0000031 PMID:19375293 http://purl.org/obo/owl/PMID#PMID_19375293 PMID:20303875 http://purl.org/obo/owl/PMID#PMID_20303875 Th1 T cell helper T cell type 1 Th1 T-cell Th1 T-lymphocyte Th1 cell Th1 T lymphocyte cell FMA:84382 http://purl.org/obo/owl/FMA#FMA_84382 BTO:0001678 http://purl.org/obo/owl/BTO#BTO_0001678 T-helper 2 cell A CD4-positive, alpha-beta T cell that has the phenotype GATA-3-positive and produces interleukin-4. GOC:add http://purl.org/obo/owl/GOC#GOC_add GOC:pam http://purl.org/obo/owl/GOC#GOC_pam GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm GO_REF:0000031 http://purl.org/obo/owl/GO_REF#GO_REF_0000031 PMID:19375293 http://purl.org/obo/owl/PMID#PMID_19375293 PMID:20103781 http://purl.org/obo/owl/PMID#PMID_20103781 Th2 cell Th2 T-cell Th2 T-lymphocyte Th2 T cell helper T cell type 2 Th2 T lymphocyte cell BTO:0001679 http://purl.org/obo/owl/BTO#BTO_0001679 FMA:84385 http://purl.org/obo/owl/FMA#FMA_84385 proerythroblast An immature, nucleated erythrocyte occupying the stage of erythropoeisis that follows formation of erythroid progenitor cells. This cell is CD71-positive, has both a nucleus and a nucleolus, and lacks hematopoeitic lineage markers. ISBN:0721601464 http://purl.org/obo/owl/ISBN#ISBN_0721601464 MESH:A.11.118.290.350.200 http://purl.org/obo/owl/MESH#MESH_A.11.118.290.350.200 PMID:1638021 http://purl.org/obo/owl/PMID#PMID_1638021 rubriblast ISBN:0721601464 http://purl.org/obo/owl/ISBN#ISBN_0721601464 pronormoblast cell FMA:83518 http://purl.org/obo/owl/FMA#FMA_83518 animal cell cell basophilic erythroblast A nucleated immature erythrocyte, having cytoplasm generally similar to that of the earlier proerythroblast but sometimes even more basophilic, and usually regular in outline. The nucleus is still relatively large, but the chromatin strands are thicker and more deeply staining, giving a coarser appearance; the nucleoli have disappeared. This cell is CD71-positive and lacks hematopoeitic lineage markers. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0721601464 http://purl.org/obo/owl/ISBN#ISBN_0721601464 prorubricyte ISBN:0721601464 http://purl.org/obo/owl/ISBN#ISBN_0721601464 early erythroblast ISBN:0721601464 http://purl.org/obo/owl/ISBN#ISBN_0721601464 basophilic normoblast ISBN:0721601464 http://purl.org/obo/owl/ISBN#ISBN_0721601464 early normoblast ISBN:0721601464 http://purl.org/obo/owl/ISBN#ISBN_0721601464 cell FMA:83505 http://purl.org/obo/owl/FMA#FMA_83505 polychromatophilic erythroblast A nucleated, immature erythrocyte in which the nucleus occupies a relatively smaller part of the cell than in its precursor, the basophilic erythroblast. The cytoplasm is beginning to acquire hemoglobin and thus is no longer a purely basophilic, but takes on acidophilic aspects, which becomes progressively more marked as the cell matures. The chromatin of the nucleus is arranged in coarse, deeply staining clumps. This cell is CD71-positive and lacks hematopoeitic lineage markers. ISBN:0721601464 http://purl.org/obo/owl/ISBN#ISBN_0721601464 rubricyte ISBN:0721601464 http://purl.org/obo/owl/ISBN#ISBN_0721601464 polychromatic normoblast ISBN:0721601464 http://purl.org/obo/owl/ISBN#ISBN_0721601464 polychromatophilic normoblast ISBN:0721601464 http://purl.org/obo/owl/ISBN#ISBN_0721601464 intermediate erythroblast ISBN:0721601464 http://purl.org/obo/owl/ISBN#ISBN_0721601464 intermediate normoblast ISBN:0721601464 http://purl.org/obo/owl/ISBN#ISBN_0721601464 polychromatic erythroblast ISBN:0721601464 http://purl.org/obo/owl/ISBN#ISBN_0721601464 cell FMA:83506 http://purl.org/obo/owl/FMA#FMA_83506 unimodal nocireceptor cell orthochromatic erythroblast The final stage of the nucleated, immature erythrocyte, before nuclear loss. Typically the cytoplasm is described as acidophilic, but it still shows a faint polychromatic tint. The nucleus is small and initially may still have coarse, clumped chromatin, as in its precursor, the polychromatophilic erythroblast, but ultimately it becomes pyknotic, and appears as a deeply staining, blue-black, homogeneous structureless mass. The nucleus is often eccentric and sometimes lobulated. ISBN:0721601464 http://purl.org/obo/owl/ISBN#ISBN_0721601464 pyknotic eto enrythroblast ISBN:0721601464 http://purl.org/obo/owl/ISBN#ISBN_0721601464 orthochromatic normoblast ISBN:0721601464 http://purl.org/obo/owl/ISBN#ISBN_0721601464 acidophilic erythroblast ISBN:0721601464 http://purl.org/obo/owl/ISBN#ISBN_0721601464 late erythoblast eosinophilic erythroblast ISBN:0721601464 http://purl.org/obo/owl/ISBN#ISBN_0721601464 cell FMA:84646 http://purl.org/obo/owl/FMA#FMA_84646 megakaryocyte progenitor cell Lineage negative is described here as CD2-negative, CD3-negative, CD4-negative, CD5-negative, CD8a-negative, CD14-negative, CD19-negative, CD20-negative, CD56-negative, Ly6g-negative, and Ter119-negative. The earliest cytologically identifiable precursor in the thrombocytic series. This cell is capable of endomitosis and lacks expression of hematopoieitic lineage markers (lin-negative). GOC:dsd http://purl.org/obo/owl/GOC#GOC_dsd GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0721601464 http://purl.org/obo/owl/ISBN#ISBN_0721601464 megakaryocytic progenitor cell PMID:12482498 http://purl.org/obo/owl/PMID#PMID_12482498 Meg-CFC PMCID:PMC1794060 http://purl.org/obo/owl/PMCID#PMCID_PMC1794060 CFU-Meg PMID:11722431 http://purl.org/obo/owl/PMID#PMID_11722431 PMID:12482498 http://purl.org/obo/owl/PMID#PMID_12482498 megakaryoblast megacaryocyte progenitor cell promegakaryocyte megacaryoblast colony-forming unit-megakaryocyte promegacaryocyte cell BTO:0001164 http://purl.org/obo/owl/BTO#BTO_0001164 FMA:84235 http://purl.org/obo/owl/FMA#FMA_84235 gastrin stimulating hormone secreting cell A peptide hormone secreting cell that secretes gastrin stimulating hormone. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm cell neuronal brush cell cell megakaryocyte Megakaryocytes are reportedly CD181-positive and CD182-positive. A giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow; mature blood platelets are released from its cytoplasm. ISBN:0721601464 http://purl.org/obo/owl/ISBN#ISBN_0721601464 MESH:D008533 http://purl.org/obo/owl/MESH#MESH_D008533 megalocaryocyte megalokaryocyte megacaryocyte cell BTO:0000843 http://purl.org/obo/owl/BTO#BTO_0000843 FMA:83555 http://purl.org/obo/owl/FMA#FMA_83555 granulocyte monocyte progenitor cell Originally described in the dendritic cell ontology (DC_CL:0000042)(PMID: 19243617). GMPs are reportedly CD34-positive, CD38-positive, CD45RA-positive, and CD123-positive. A hematopoietic progenitor cell that is committed to the granulocyte and monocyte lineages. These cells are CD123-positive, and do not express Gata-1, Gata2 but do express C/EBPa, and Pu.1. GOC:amm http://purl.org/obo/owl/GOC#GOC_amm GOC:dsd http://purl.org/obo/owl/GOC#GOC_dsd GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm GO_REF:0000031 http://purl.org/obo/owl/GO_REF#GO_REF_0000031 ISBN:0721601464 http://purl.org/obo/owl/ISBN#ISBN_0721601464 MESH:D055014 http://purl.org/obo/owl/MESH#MESH_D055014 PMCID:PMC2213186 http://purl.org/obo/owl/PMCID#PMCID_PMC2213186 PMCID:PMC548021 http://purl.org/obo/owl/PMCID#PMCID_PMC548021 PMID:16551251 http://purl.org/obo/owl/PMID#PMID_16551251 URL:http://www.copewithcytokines.de http://www.copewithcytokines.de colony forming unit granulocyte macrophage ISBN:0721601464 http://purl.org/obo/owl/ISBN#ISBN_0721601464 PMCID:PMC2213186 http://purl.org/obo/owl/PMCID#PMCID_PMC2213186 PMCID:PMC548021 http://purl.org/obo/owl/PMCID#PMCID_PMC548021 GMP ISBN:0721601464 http://purl.org/obo/owl/ISBN#ISBN_0721601464 PMCID:PMC2213186 http://purl.org/obo/owl/PMCID#PMCID_PMC2213186 PMCID:PMC548021 http://purl.org/obo/owl/PMCID#PMCID_PMC548021 CFU-C , Colony forming unit in culture URL:http://www.copewithcytokines.de http://www.copewithcytokines.de granulocyte-macrophage progenitor ISBN:0721601464 http://purl.org/obo/owl/ISBN#ISBN_0721601464 PMCID:PMC2213186 http://purl.org/obo/owl/PMCID#PMCID_PMC2213186 PMCID:PMC548021 http://purl.org/obo/owl/PMCID#PMCID_PMC548021 CFU-GM ISBN:0721601464 http://purl.org/obo/owl/ISBN#ISBN_0721601464 PMCID:PMC2213186 http://purl.org/obo/owl/PMCID#PMCID_PMC2213186 PMCID:PMC548021 http://purl.org/obo/owl/PMCID#PMCID_PMC548021 cell reticulocyte An immature erythrocyte that changes the protein composition of its plasma membrane by exosome formation and extrusion. The types of protein removed differ between species though removal of the transferrin receptor is apparent in mammals and birds. GOC:add http://purl.org/obo/owl/GOC#GOC_add GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm PMID:15946868 http://purl.org/obo/owl/PMID#PMID_15946868 PMID:2037622 http://purl.org/obo/owl/PMID#PMID_2037622 cell BTO:0001173 http://purl.org/obo/owl/BTO#BTO_0001173 promonocyte Morphology: Mononuclear cell, diameter 14-18 _M, fine azurophilic granules; markers: CD11b (shared with many other myeloid cells); location: Adult: bone marrow; Fetal: Liver, Yolk Sac; role or process: hematopoiesis, monocyte development; lineage: hematopoietic, myeloid. A precursor in the monocytic series, being a cell intermediate in development between the monoblast and monocyte. This cell is CD11b-positive and has fine azurophil granules. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0721601464 http://purl.org/obo/owl/ISBN#ISBN_0721601464 URL:http://www.clt.astate.edu/wwilliam/ http://www.clt.astate.edu/wwilliam/ cell FMA:83551 http://purl.org/obo/owl/FMA#FMA_83551 BTO:0004657 http://purl.org/obo/owl/BTO#BTO_0004657 band form neutrophil They are found in the Band 1 fraction. A late neutrophilic metamyelocyte in which the nucleus is indented to more than half the distance to the farthest nuclear margin but in no area being condensed to a single filament. The nucleus is in the form of a curved or coiled band, not having acquired the typical multilobar shape of the mature neutrophil. These cells are fMLP receptor-positive, CD11b-positive, CD35-negative, and CD49d-negative. GOC:add http://purl.org/obo/owl/GOC#GOC_add GOC:dsd http://purl.org/obo/owl/GOC#GOC_dsd GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0721601464 http://purl.org/obo/owl/ISBN#ISBN_0721601464 PMID:10618520 http://purl.org/obo/owl/PMID#PMID_10618520 PMID:12560239 http://purl.org/obo/owl/PMID#PMID_12560239 PMID:15514007 http://purl.org/obo/owl/PMID#PMID_15514007 URL:http://www.cap.org http://www.cap.org band rod neutrophil stab cell band cell band form cell amacrine cell Not clear if this term overlaps with retinal bipolar neuron (CL:0000748). Interneuron of the vertebrate retina. They integrate, modulate, and interpose a temporal domain in the visual message presented to the retinal ganglion cells, with which they synapse in the inner plexiform layer. They lack large axons. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm MESH:A.08.663.358.050 http://purl.org/obo/owl/MESH#MESH_A.08.663.358.050 amacrine neuron cell FBbt:00005127 http://purl.org/obo/owl/FBbt#FBbt_00005127 BTO:0004044 http://purl.org/obo/owl/BTO#BTO_0004044 FMA:67766 http://purl.org/obo/owl/FMA#FMA_67766 nucleate erythrocyte An erythrocyte having a nucleus. GOC:add http://purl.org/obo/owl/GOC#GOC_add GOc:tfm http://purl.org/obo/owl/GOc#GOc_tfm RBC red blood cell cell endospore A rounded, inactive form that certain bacteria assume under conditions of extreme temperature, dryness, or lack of food. The bacterium develops a waterproof cell wall that protects it from being dried out or damaged. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0618947256 http://purl.org/obo/owl/ISBN#ISBN_0618947256 bacterial spore cell BTO:0002779 http://purl.org/obo/owl/BTO#BTO_0002779 neutrophilic promyelocyte These cells are CD11b-negative, CD15-positive, CD16-negative, CD49d-positive, CD68-positive, CD35-negative, and fMLP receptor-negative. They are found in the Band 3 fraction. A promyelocyte committed to the neutrophil lineage. This cell type is GATA-1-positive, C/EBPa-positive, AML-1-positive, MPO-positive, has low expression of PU.1 transcription factor and lacks lactotransferrin expression. GOC:add http://purl.org/obo/owl/GOC#GOC_add GOC:dsd http://purl.org/obo/owl/GOC#GOC_dsd GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0721601464 http://purl.org/obo/owl/ISBN#ISBN_0721601464 PMID:12560239 http://purl.org/obo/owl/PMID#PMID_12560239 PMID:15514007 http://purl.org/obo/owl/PMID#PMID_15514007 neutrophilic progranulocyte neutrophilic premyelocyte cell FMA:84196 http://purl.org/obo/owl/FMA#FMA_84196 fat body cell A cell whose primary function is intermediary metabolism. FB:ma http://purl.org/obo/owl/FB#FB_ma cell angioblastic mesenchymal cell These cells are reportedly CD31-positive, CD34-positive, CD144-positive, CD309-positive, and TAL1-positive. A mesenchymal stem cell capable of developing into blood vessel endothelium. GOC:dsd http://purl.org/obo/owl/GOC#GOC_dsd GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm PMID:12768659 http://purl.org/obo/owl/PMID#PMID_12768659 chondroplast angioblast cell polymodal nocireceptor cell APUD cell A cell that originates in the neural crest, that has certain cytochemical and ultrastructural characteristics and is found scattered throughout the body; types include melanocytes, the cells of the chromaffin system, and cells in the hypothalamus, hypophysis, thyroid, parathyroids, lungs, gastrointestinal tract, and pancreas. THis cell type concentrates the amino acid precursors of certain amines and decarboxylate them, forming amines that function as regulators and neurotransmitters. This cell type produces substances such as epinephrine, norepinephrine, dopamine, serotonin, enkephalin, somatostatin, neurotensin, and substance P, the actions of which may affect contiguous cells, nearby groups of cells, or distant cells, thus functioning as local or systemic hormones. The name is an acronym for amine precursor uptake and decarboxylation cell. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0721662544 http://purl.org/obo/owl/ISBN#ISBN_0721662544 MESH:A.11.070 http://purl.org/obo/owl/MESH#MESH_A.11.070 Amine precursor uptake and decarboxylation cell cell FMA:83114 http://purl.org/obo/owl/FMA#FMA_83114 BTO:0003866 http://purl.org/obo/owl/BTO#BTO_0003866 cardiac mesenchymal cell A mesenchymal cell found in the developing heart. PMID:18816864 http://purl.org/obo/owl/PMID#PMID_18816864 cell parafollicular cell A neuroepithelial cells that occurs singly or in small groups, close to the outer follicular borders but within the follicular basement membrane of the thyroid. Expresses a form of the neural cell adhesion molecule (N-CAM) on their surface. Secrets calcitonin, 5-hydroxytryptamine and dopamine. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0517223651 http://purl.org/obo/owl/ISBN#ISBN_0517223651 C cell cell FMA:68653 http://purl.org/obo/owl/FMA#FMA_68653 leucophore A pigment cell derived from the neural crest. Contains uric acid or other purine crystals deposited in stacks called leucosomes. The crystals reflect light and this gives a white appearance under white light. SANBI:mhl http://purl.org/obo/owl/SANBI#SANBI_mhl cell retinal cone cell One of the two photoreceptor cell types in the vertebrate retina. In cones the photopigment is in invaginations of the cell membrane of the outer segment. Cones are less sensitive to light than rods, but they provide vision with higher spatial and temporal acuity, and the combination of signals from cones with different pigments allows color vision. MESH:A.08.663.650.650.670.100 http://purl.org/obo/owl/MESH#MESH_A.08.663.650.650.670.100 cell BTO:0001036 http://purl.org/obo/owl/BTO#BTO_0001036 FMA:67748 http://purl.org/obo/owl/FMA#FMA_67748 erythrophore A pigment cell derived from the neural crest. Contains pteridine and/or carotenoid pigments in structures called pterinosomes or erythrosomes. This gives an orange to red appearance. SANBI:mhl http://purl.org/obo/owl/SANBI#SANBI_mhl cell corneal epithelial cell An epithelial cell of the cornea. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm epithelial cell of cornea FMA:70551 http://purl.org/obo/owl/FMA#FMA_70551 cell CL:1000431 FMA:70551 http://purl.org/obo/owl/FMA#FMA_70551 BTO:0004298 http://purl.org/obo/owl/BTO#BTO_0004298 monocyte Morphology: Mononuclear cell, diameter, 14 to 20 _M, N/C ratio 2:1-1:1. Nucleus may appear in variety of shapes: round, kidney, lobulated, or convoluted. Fine azurophilic granules present; markers: CD11b (shared with other myeloid cells), human: CD14, mouse: F4/80-mid,GR1-low; location: Blood, but can be recruited into tissues; role or process: immune & tissue remodelling; lineage: hematopoietic, myeloid. Myeloid mononuclear recirculating leukocyte that can act as a precursor of tissue macrophages, osteoclasts and some populations of tissue dendritic cells. GO_REF:0000031 http://purl.org/obo/owl/GO_REF#GO_REF_0000031 MESH:A.11.118.637.555.652 http://purl.org/obo/owl/MESH#MESH_A.11.118.637.555.652 URL:http://www.clt.astate.edu/wwilliam/ http://www.clt.astate.edu/wwilliam/ cell BTO:0000876 http://purl.org/obo/owl/BTO#BTO_0000876 FMA:62864 http://purl.org/obo/owl/FMA#FMA_62864 type EC enteroendocrine cell A subtype of enteroendocrine cells found in the gastrointestinal mucosa, particularly in the glands of pyloric antrum; duodenum; and ileum. These cell type secretes serotonin and some neurotransmitters including enkephalins and substance P. Their secretory granules stain readily with silver (argentaffin stain). MESH:A.03.492.766.440.250 http://purl.org/obo/owl/MESH#MESH_A.03.492.766.440.250 PMID:9505449 http://purl.org/obo/owl/PMID#PMID_9505449 argentaffin cell Kulchitsky cell enterochromaffin cell cell CL:0002065 FMA:62934 http://purl.org/obo/owl/FMA#FMA_62934 experimentally modified cell A cell that has been changed as a consequence of a deliberate and specific experimental procedure. FB:ma http://purl.org/obo/owl/FB#FB_ma cell border follicle cell cell FBbt:00004905 http://purl.org/obo/owl/FBbt#FBbt_00004905 neutrophilic myelocyte These cells are also CD15-positive, CD35-negative, CD49d-positive, and fMLP receptor-negative. They are found in the Band 2 fraction. A neutrophil precursor in the granulocytic series, being a cell intermediate in development between a promyelocyte and a metamyelocyte; in this stage, production of primary granules is complete and neutrophil-specific granules has started. No nucleolus is present. This cell type is CD13-positive, CD16-negative, integrin alpha-M-positive, CD15-positive, CD33-positive, CD24-positive, C/EBP-a-positive, C/EBPe-positive, PU.1-positive, lactotransferrin-positive, myeloperoxidase-positive and NGAL-positive. GOC:add http://purl.org/obo/owl/GOC#GOC_add GOC:dsd http://purl.org/obo/owl/GOC#GOC_dsd GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0721601464 http://purl.org/obo/owl/ISBN#ISBN_0721601464 PMID:10618520 http://purl.org/obo/owl/PMID#PMID_10618520 PMID:12560239 http://purl.org/obo/owl/PMID#PMID_12560239 PMID:15514007 http://purl.org/obo/owl/PMID#PMID_15514007 URL:http://www.cap.org http://www.cap.org cell FMA:83540 http://purl.org/obo/owl/FMA#FMA_83540 BTO:0003455 http://purl.org/obo/owl/BTO#BTO_0003455 peritoneal macrophage Markers: Mouse: F4/80-high, CD11b-high, CD68+, SIGNR1+, Dectin-1+. A macrophage resident in the peritoneum under non-inflammatory conditions. Markers include F4/80-high, CD11b-high, CD68-positive, SIGNR1-positive, CD115-high, MHC-II-negative, and Dectin-1-positive. MESH:A.11.329.372.630 http://purl.org/obo/owl/MESH#MESH_A.11.329.372.630 PMID:15771589 http://purl.org/obo/owl/PMID#PMID_15771589 PMID:19201820 http://purl.org/obo/owl/PMID#PMID_19201820 cell BTO:0001034 http://purl.org/obo/owl/BTO#BTO_0001034 FMA:83025 http://purl.org/obo/owl/FMA#FMA_83025 neutrophilic metamyelocyte These cells are also CD35-negative, CD49d-positive, and fMLP receptor-negative. They are found in the Band 2 fraction. A neutrophil precursor in the granulocytic series, being a cell intermediate in development between a myelocyte and the band form neutrophil. The protein synthesis seen in earlier stages decreases or stops; the nucleus becomes indented where the indentation is smaller than half the distance to the farthest nuclear margin; chromatin becomes coarse and clumped; specific granules predominate while primary granules are rare; and the cytoplasm becomes amphophilic like that of a mature granulocyte. This cell type is integrin alpha-M-positive, CD13-negative, CD15-positive, CD16-positive, CD33-positive, CD24-positive, fMLP receptor-negative and has expression of C/EBP-a, C/EBP-e, PU.1 transcription factor, lactotransferrin, myeloperoxidase and neutrophil gelatinase associated lipocalin. GOC:add http://purl.org/obo/owl/GOC#GOC_add GOC:dsd http://purl.org/obo/owl/GOC#GOC_dsd GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0721601464 http://purl.org/obo/owl/ISBN#ISBN_0721601464 PMID:10618520 http://purl.org/obo/owl/PMID#PMID_10618520 PMID:12560239 http://purl.org/obo/owl/PMID#PMID_12560239 PMID:15514007 http://purl.org/obo/owl/PMID#PMID_15514007 URL:http://www.cap.org http://www.cap.org juvenile neutrophil cell FMA:84197 http://purl.org/obo/owl/FMA#FMA_84197 alveolar macrophage Markers: Mouse: F4/80mid, CD11b-/low, CD11c+, CD68+, sialoadhesin+, dectin-1+, MR+, CX3CR1-. A tissue-resident macrophage found in the alveoli of the lungs. Ingests small inhaled particles resulting in degradation and presentation of the antigen to immunocompetent cells. Markers include F4/80-positive, CD11b-/low, CD11c-positive, CD68-positive, sialoadhesin-positive, dectin-1-positive, MR-positive, CX3CR1-negative. GOC:ana http://purl.org/obo/owl/GOC#GOC_ana GOC:dsd http://purl.org/obo/owl/GOC#GOC_dsd GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm GO_REF:0000031 http://purl.org/obo/owl/GO_REF#GO_REF_0000031 MESH:A.11.329.372.600 http://purl.org/obo/owl/MESH#MESH_A.11.329.372.600 dust cell MF.Lu cell FMA:83023 http://purl.org/obo/owl/FMA#FMA_83023 BTO:0000802 http://purl.org/obo/owl/BTO#BTO_0000802 enterocyte An epithelial cell that has its apical plasma membrane folded into microvilli to provide ample surface for the absorption of nutrients from the intestinal lumen. SANBI:mhl http://purl.org/obo/owl/SANBI#SANBI_mhl cell FMA:62122 http://purl.org/obo/owl/FMA#FMA_62122 BTO:0000398 http://purl.org/obo/owl/BTO#BTO_0000398 null cell This term is rather archaic; consider using 'natural killer cell ; CL:0000623', 'pro-B cell ; CL:0000826', 'pro-T cell ; CL:0000827', or other appropriate lymphocyte-related term depending on the context. OBSOLETE: A class of lymphocytes characterized by the lack of surface markers specific for either T or B cells. cell germ cell The reproductive cell in multicellular organisms. MESH:A.05.360.490 http://purl.org/obo/owl/MESH#MESH_A.05.360.490 cell BTO:0000535 http://purl.org/obo/owl/BTO#BTO_0000535 cold sensing thermoreceptor cell A thermoreceptor cell that detects reduced temperatures. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm cell odontoclast A specialized osteoclast associated with the absorption and removal of cementum. GOC:add http://purl.org/obo/owl/GOC#GOC_add MESH:A.11.329.679 http://purl.org/obo/owl/MESH#MESH_A.11.329.679 cell BTO:0002516 http://purl.org/obo/owl/BTO#BTO_0002516 FMA:83027 http://purl.org/obo/owl/FMA#FMA_83027 cochlear inner hair cell A bulbous cell that is medially placed in one row in the organ of Corti. In contrast to the outer hair cells, the inner hair cells are fewer in number, have fewer sensory hairs, and are less differentiated. MESH:A.08.663.650.250.250 http://purl.org/obo/owl/MESH#MESH_A.08.663.650.250.250 inner hair cell cell FMA:62365 http://purl.org/obo/owl/FMA#FMA_62365 BTO:0003667 http://purl.org/obo/owl/BTO#BTO_0003667 small luteal cell A progesterone secreting cell in the corpus luteum that develops from theca cells. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm MESH:A.05.360.319.114.630.278.400 http://purl.org/obo/owl/MESH#MESH_A.05.360.319.114.630.278.400 Theca lutein cell small lutein cell cell BTO:0002850 http://purl.org/obo/owl/BTO#BTO_0002850 FMA:18690 http://purl.org/obo/owl/FMA#FMA_18690 warmth sensing thermoreceptor cell A thermoreceptor cell that detects reduced temperatures. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm cell large luteal cell A large, progesterone secreting cell in the corpus luteum that develops from the granulosa cells. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm MESH:A.05.360.319.114.630.278.400 http://purl.org/obo/owl/MESH#MESH_A.05.360.319.114.630.278.400 Granulosoluteocytus Granulosa lutein cell cell FMA:18689 http://purl.org/obo/owl/FMA#FMA_18689 androgen secreting cell A steroid hormone secreting cell that secretes androgen. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm cell skeletal muscle satellite cell An elongated, spindle-shaped, quiescent myoblast that are located between the basal lamina and the plasmalemma of the muscle fibres. They are thought to play a role in muscle repair and regeneration. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm MESH:A.11.635.500.700 http://purl.org/obo/owl/MESH#MESH_A.11.635.500.700 cell enucleate erythrocyte An erythrocyte lacking a nucleus. GOC:add http://purl.org/obo/owl/GOC#GOC_add GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm red blood cell RBC cell sexual spore A spore formed following meiosis. Sometimes following meiosis, prospores may undergo one or more rounds of mitosis before they are fully mature. FAO:0000017 http://purl.org/obo/owl/FAO#FAO_0000017 GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm SGD:clt http://purl.org/obo/owl/SGD#SGD_clt meiotically-derived spore cell FAO:0000017 http://purl.org/obo/owl/FAO#FAO_0000017 microconidium The smaller of two types of asexual spores formed by some fungi. An ovoid to pear-shaped asexual spore that contains very little cytoplasm and organelles, is uninucleate, and forms in vegetative hypae within a mycelium. Micronidia are extruded from the hyphal cell wall. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0471940526 http://purl.org/obo/owl/ISBN#ISBN_0471940526 PMID:8357339 http://purl.org/obo/owl/PMID#PMID_8357339 SGD:clt http://purl.org/obo/owl/SGD#SGD_clt cell FAO:0000028 http://purl.org/obo/owl/FAO#FAO_0000028 pyramidal cell A projection neuron in the cerebral cortex and the hippocampus. Pyramidal cells have a pyramid-shaped soma with the apex and an apical dendrite pointed toward the pial surface and other dendrites and an axon emerging from the base. The axons may have local collaterals but also project outside their cortical region. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm MESH:A.08.186.211.577.405.700 http://purl.org/obo/owl/MESH#MESH_A.08.186.211.577.405.700 projection neuron pyramidal neuron cell BTO:0003102 http://purl.org/obo/owl/BTO#BTO_0003102 FMA:86775 http://purl.org/obo/owl/FMA#FMA_86775 conidium An asexual, nonmotile spore formed by higher fungi; conidia are usually made from the side or tip of specialized sporogenous cells and do not form by progressive cleavage of the cytoplasm. ISBN:08199377X http://purl.org/obo/owl/ISBN#ISBN_08199377X PMID:2524423 http://purl.org/obo/owl/PMID#PMID_2524423 PMID:9529886 http://purl.org/obo/owl/PMID#PMID_9529886 SGD:clt http://purl.org/obo/owl/SGD#SGD_clt cell FAO:0000024 http://purl.org/obo/owl/FAO#FAO_0000024 BTO:0000283 http://purl.org/obo/owl/BTO#BTO_0000283 heterokaryon A fungal cell with two or more genetically distinct nuclei. ISBN:08199377X http://purl.org/obo/owl/ISBN#ISBN_08199377X cell outer hair cell A mechanoreceptor in the organ of Corti. In mammals the outer hair cells are arranged in three rows which are further from the modiolus than the single row of inner hair cells. The motile properties of the outer hair cells may contribute actively to tuning the sensitivity and frequency selectivity of the cochlea. MESH:A.08.663.650.250.315 http://purl.org/obo/owl/MESH#MESH_A.08.663.650.250.315 cochlear outer hair cell cell BTO:0003666 http://purl.org/obo/owl/BTO#BTO_0003666 FMA:62366 http://purl.org/obo/owl/FMA#FMA_62366 pressoreceptor cell A receptor in the vascular system, particularly the aorta and carotid sinus, which is sensitive to stretch of the vessel walls. MESH:A.08.800.050.800.900.700 http://purl.org/obo/owl/MESH#MESH_A.08.800.050.800.900.700 cell dikaryon A fungal cell with two genetically distinct haploid nuclei. ISBN:08199377X http://purl.org/obo/owl/ISBN#ISBN_08199377X cell retinal rod cell One of the two photoreceptor cell types of the vertebrate retina. In rods the photopigment is in stacks of membranous disks separate from the outer cell membrane. Rods are more sensitive to light than cones, but rod mediated vision has less spatial and temporal resolution than cone vision. MESH:A.08.663.650.650.670.650 http://purl.org/obo/owl/MESH#MESH_A.08.663.650.650.670.650 cell FMA:67747 http://purl.org/obo/owl/FMA#FMA_67747 BTO:0001024 http://purl.org/obo/owl/BTO#BTO_0001024 fungal asexual spore A spore formed following mitosis or mitoses. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm PMID:2524423 http://purl.org/obo/owl/PMID#PMID_2524423 PMID:9529886 http://purl.org/obo/owl/PMID#PMID_9529886 SGD:clt http://purl.org/obo/owl/SGD#SGD_clt cell FAO:0000023 http://purl.org/obo/owl/FAO#FAO_0000023 macroconidium The larger of two types of asexual spores formed by some fungi; usually round or oblong. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0471940526 http://purl.org/obo/owl/ISBN#ISBN_0471940526 SGD:clt http://purl.org/obo/owl/SGD#SGD_clt cell FAO:0000038 http://purl.org/obo/owl/FAO#FAO_0000038 ascospore A thick walled spore that stores and protects one or more nuclei following sexual reproduction in an Ascomycete. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:08199377X http://purl.org/obo/owl/ISBN#ISBN_08199377X SGD:clt http://purl.org/obo/owl/SGD#SGD_clt cell FAO:0000020 http://purl.org/obo/owl/FAO#FAO_0000020 BTO:0000097 http://purl.org/obo/owl/BTO#BTO_0000097 zygospore A thick walled, sexual, resting spore formed by Zygomycetes; sometimes refers to the spore and the multi-layered cell wall that encloses the spore, the zygosporangium. ISBN:0471940526 http://purl.org/obo/owl/ISBN#ISBN_0471940526 ISBN:08199377X http://purl.org/obo/owl/ISBN#ISBN_08199377X SGD:clt http://purl.org/obo/owl/SGD#SGD_clt cell FAO:0000040 http://purl.org/obo/owl/FAO#FAO_0000040 vestibular hair cell A mechanoreceptor located in the acoustic maculae and the semicircular canals that mediates the sense of balance, movement, and head position. The vestibular hair cells are connected to accessory structures in such a way that movements of the head displace their stereocilia. This influences the membrane potential of the cells which relay information about movements via the vestibular part of the vestibulocochlear nerve to the brain stem. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm MESH:A.08.663.650.250.380 http://purl.org/obo/owl/MESH#MESH_A.08.663.650.250.380 vestibular receptor cell cell FMA:62351 http://purl.org/obo/owl/FMA#FMA_62351 plant cell A cell found in seeded plants. Descendants of this cell type are represented in the Plant Ontology (PO). GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm TAIR:syr http://purl.org/obo/owl/TAIR#TAIR_syr cell PO:0009002 http://purl.org/obo/owl/PO#PO_0009002 eosinophil progenitor cell These cells are CD34-positive, CD45RA-negative, CD71-negative, and lineage-negative (CD2, CD3 epsilon, CD4, CD5, CD8a, CD14, CD19, CD20, integrin alpha-M, NCAM-1, SCA-1, Ly6G, Ly76). CFU-Eo eosinophil stem cell EoP PMCID:PMC2212039 http://purl.org/obo/owl/PMCID#PMCID_PMC2212039 PMCID:PMC2626675 http://purl.org/obo/owl/PMCID#PMCID_PMC2626675 colony forming unit eosinophil cell eosinophilic myelocyte A eosinophil precursor in the granulocytic series, being a cell intermediate in development between a promyelocyte and a metamyelocyte;in this stage, production of primary granules is complete and eosinophil-specific granules has started. No nucleolus is present. These cells are integrin alpha-M-positive, CD13-positive, CD15-positive, CD16-negative, CD24-positive, and CD33-positive. GOC:add http://purl.org/obo/owl/GOC#GOC_add GOC:dsd http://purl.org/obo/owl/GOC#GOC_dsd ISBN:0721601464 http://purl.org/obo/owl/ISBN#ISBN_0721601464 PMID:19622087 http://purl.org/obo/owl/PMID#PMID_19622087 URL:http://www.cap.org http://www.cap.org cell BTO:0003454 http://purl.org/obo/owl/BTO#BTO_0003454 FMA:83542 http://purl.org/obo/owl/FMA#FMA_83542 basophil progenitor cell BaP are also CD13-low and integrin beta-7-low. They are lin-negative (CD2, CD3e, CD4, CD5, CD8, CD11b, CD14, CD19, CD20, ly6g, ly76, and NCAM-1). They also lack expression of mast cell protease 1 (MCP-1) and microphthalmia-associated transcription factor (mitf). A progenitor cell committed to the basophil lineage. This cell lacks hematopoietic lineage markers (lin-negative) and is CD34-positive, T1/ST2-low, CD117-negative, and FceRIa-high. This cell also expresses Gata-1, Gata-2 and C/EBPa. GOC:add http://purl.org/obo/owl/GOC#GOC_add GOC:dsd http://purl.org/obo/owl/GOC#GOC_dsd PMCID:PMC1312421 http://purl.org/obo/owl/PMCID#PMCID_PMC1312421 URL:http://www.copewithcytokines.de http://www.copewithcytokines.de basophilic stem cell colony forming unit basophil CFU-Bas BaP cell basophilic myelocyte A basophil precursor in the granulocytic series, being a cell intermediate in development between a promyelocyte and a metamyelocyte; in this stage, production of primary granules is complete and basophil-specific granules has started. No nucleolus is present. Markers are being integrin alpha-M-positive, fucosyltransferase FUT4-positive, CD33-positive, CD24-positive, aminopeptidase N-positive. GOC:add http://purl.org/obo/owl/GOC#GOC_add GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0721601464 http://purl.org/obo/owl/ISBN#ISBN_0721601464 PMID:18466030 http://purl.org/obo/owl/PMID#PMID_18466030 URL:http://www.cap.org http://www.cap.org cell BTO:0003456 http://purl.org/obo/owl/BTO#BTO_0003456 FMA:83543 http://purl.org/obo/owl/FMA#FMA_83543 basidiospore A thick walled spore containing one or more haploid nuclei produced by sexual reproduction in an Basidiomycete; formed externally on extrusions of the basidium. GOC:clt http://purl.org/obo/owl/GOC#GOC_clt ISBN:0471940526 http://purl.org/obo/owl/ISBN#ISBN_0471940526 ISBN:08199377X http://purl.org/obo/owl/ISBN#ISBN_08199377X cell FAO:0000021 http://purl.org/obo/owl/FAO#FAO_0000021 BTO:0002166 http://purl.org/obo/owl/BTO#BTO_0002166 sporangiospore A walled spore produced in a sporangium. ISBN:08199377X http://purl.org/obo/owl/ISBN#ISBN_08199377X cell GABAergic neuron A neuron that uses GABA as a vesicular neurotransmitter GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm GABA-ergic neuron cell FMA:84788 http://purl.org/obo/owl/FMA#FMA_84788 WBbt:0005190 http://purl.org/obo/owl/WBbt#WBbt_0005190 sheath cell cell support cell (sensu Nematoda) cell zoospore A sporangiospore that is motile, having flagella. ISBN:08199377X http://purl.org/obo/owl/ISBN#ISBN_08199377X cell FAO:0000039 http://purl.org/obo/owl/FAO#FAO_0000039 fusion competent myoblast cell acinar cell A secretory cell that is grouped together with other cells of the same type to form grape shaped clusters known as acini (singular acinus). GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm URL:http://www.copewithcytokines.de http://www.copewithcytokines.de acinous cell acinic cell cell FMA:83625 http://purl.org/obo/owl/FMA#FMA_83625 natural killer cell A lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation via germline encoded activation receptors and also regulate immune responses via cytokine release and direct contact with other cells. GOC:add http://purl.org/obo/owl/GOC#GOC_add ISBN:0781735149 http://purl.org/obo/owl/ISBN#ISBN_0781735149 PMID:15771571 http://purl.org/obo/owl/PMID#PMID_15771571 null cell large granular lymphocyte NK cell cell FMA:63147 http://purl.org/obo/owl/FMA#FMA_63147 BTO:0000914 http://purl.org/obo/owl/BTO#BTO_0000914 FMA:83601 http://purl.org/obo/owl/FMA#FMA_83601 BTO:0004716 http://purl.org/obo/owl/BTO#BTO_0004716 CD4-positive, alpha-beta T cell A mature alpha-beta T cell that expresses an alpha-beta T cell receptor and the CD4 coreceptor. GOC:add http://purl.org/obo/owl/GOC#GOC_add ISBN:0781735149 http://purl.org/obo/owl/ISBN#ISBN_0781735149 CD4-positive, alpha-beta T-cell CD4-positive, alpha-beta T lymphocyte CD4-positive, alpha-beta T-lymphocyte cell CD8-positive, alpha-beta T cell A T cell expressing an alpha-beta T cell receptor and the CD8 coreceptor. GOC:add http://purl.org/obo/owl/GOC#GOC_add GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0781735149 http://purl.org/obo/owl/ISBN#ISBN_0781735149 CD8-positive, alpha-beta T-lymphocyte CD8-positive, alpha-beta T-cell CD8-positive, alpha-beta T lymphocyte cell olfactory granule cell Granule cell that is part of the olfactory bulb. GOC:mah http://purl.org/obo/owl/GOC#GOC_mah cell transporting cell A cell involved in transporting nutrients, minerals, water, gases and other chemicals between cells for a variety of purposes including conveying nutrition to other tissues, removing waste products from the tissues, conveying gases for respiration, distributing heat and repelling invasion of foreign substances. TAIR:sr http://purl.org/obo/owl/TAIR#TAIR_sr cell photosynthetic cell A cell that can perform photosynthesis, in which carbohydrates are synthesized from carbon dioxide and water, using light as the energy source. TAIR:sr http://purl.org/obo/owl/TAIR#TAIR_sr cell storage cell A cell that is specialized to store a particular substance(s), which is(are) later released from the store for a particular purpose. FB:ma http://purl.org/obo/owl/FB#FB_ma cell supportive cell A cell whose primary function is to support other cell types. FB:ma http://purl.org/obo/owl/FB#FB_ma GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm cell BTO:0002315 http://purl.org/obo/owl/BTO#BTO_0002315 FMA:86947 http://purl.org/obo/owl/FMA#FMA_86947 labyrinth supporting cell Cells forming a framework supporting the organ of Corti. Specific cells are those of Claudius, Deiters and Hensen. MESH:A.09.246.631.246.577.543 http://purl.org/obo/owl/MESH#MESH_A.09.246.631.246.577.543 cell hepatic stellate cell Hepatic stellate cells are CD271-positive, desmin-positive, DDR-2-positive, GFAP-positive, synamin-positive, synaptophysin-positive, vimentin-positive, They are capable of producing angiotensin II, fibronectin, laminin, MMP-1, MMP-2, MMP-3, MMP-9, MMP-11, TGF-beta1, TIMP-1, TIMP-2, type I collagen, type III collagen, type IV collagen, and type VI collagen. A cell that is found in the perisinusoidal space of the liver that is capable of multiple roles including storage of retinol, presentation of antigen to T cells (including CD1d-restricted NKT cells), and upon activation, production of extracellular matrix components that can contribute to liver fibrosis. This activated state has a myofibroblast-like phenotype, though it's not clear in the literature if this is terminally differentiated. This cell type comprises approximately 8-15% of total cells in the liver. GOC:dsd http://purl.org/obo/owl/GOC#GOC_dsd MESH:D055166 http://purl.org/obo/owl/MESH#MESH_D055166 PMID:12808230 http://purl.org/obo/owl/PMID#PMID_12808230 PMID:17239632 http://purl.org/obo/owl/PMID#PMID_17239632 PMID:18222966 http://purl.org/obo/owl/PMID#PMID_18222966 PMID:9302568 http://purl.org/obo/owl/PMID#PMID_9302568 lipocyte fat-storing cell hepatic perisinusoidal cell vitamin A-storing cells PMID:12808230 http://purl.org/obo/owl/PMID#PMID_12808230 perisinusoidal cell Ito cell cell BTO:0002741 http://purl.org/obo/owl/BTO#BTO_0002741 FMA:67763 http://purl.org/obo/owl/FMA#FMA_67763 Hensen cell A tall supporting cell that is arranged in rows adjacent to the last row of outer phalangeal cells. This cell type constitutes the outer border of the organ of Corti. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0721662544 http://purl.org/obo/owl/ISBN#ISBN_0721662544 External limiting cell of organ of Corti Cell of Hensen Hensen's cell cell FMA:79799 http://purl.org/obo/owl/FMA#FMA_79799 Claudius cell A cuboidal cell which along with Boettcher's cells form the floor of the external spiral sulcus, external to the organ of Corti. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0721662544 http://purl.org/obo/owl/ISBN#ISBN_0721662544 Cell of Claudius External supporting cell of Claudius External supporting cell of vestibular epithelium Claudius cell cell FMA:79802 http://purl.org/obo/owl/FMA#FMA_79802 Deiter's cell The outer phalangeal cells of the organ of Corti. This cell holds the base of the hair cell in a cup-shaped depression. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0721662544 http://purl.org/obo/owl/ISBN#ISBN_0721662544 URL:http://www.britannica.com/EBchecked/topic/156177/Deiters-cell http://www.britannica.com/EBchecked/topic/156177/Deiters-cell outer phalangeal cell Deiters cell cell FMA:75725 http://purl.org/obo/owl/FMA#FMA_75725 Mueller cell cell BTO:0003064 http://purl.org/obo/owl/BTO#BTO_0003064 chromophil cell of anterior pituitary gland A cell that stains readily in the anterior pituitary gland. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0618947256 http://purl.org/obo/owl/ISBN#ISBN_0618947256 cell FMA:83089 http://purl.org/obo/owl/FMA#FMA_83089 acidophil cell of pars distalis of adenohypophysis An acidophilic chromophil cell that of the anterior pituitary gland. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm Pituitary alpha cell Acidophil cell of pars anterior of adenohypophysis Acidophil of pars distalis of adenohypophysis Acidophil of pars anterior of adenohypophysis cell FMA:83093 http://purl.org/obo/owl/FMA#FMA_83093 basophil cell of pars distalis of adenohypophysis A basophillic chromophil cell that of the anterior pituitary gland. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm beta cell basophil cell of anterior lobe of hypophysis cell FMA:83094 http://purl.org/obo/owl/FMA#FMA_83094 chromophobe cell A cell that is resistant to stains. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm chromophobic cell cell FMA:83626 http://purl.org/obo/owl/FMA#FMA_83626 folliculostellate cell A supportive cell of the vertebrate pituitary that provides macromolecular transport and secretes hormones. JB:jb http://purl.org/obo/owl/JB#JB_jb cell Bergmann glial cell Type of radial astrocyte in the cerebellar cortex that have their cell bodies in the Purkinje cell layer and processes that extend into the molecular layer, terminating with bulbous endfeet at the pial surface. Bergmann glia express high densities of glutamate transporters that limit diffusion of the neurotransmitter glutamate during its release from synaptic terminals. Besides their role in early development of the cerebellum, Bergmann glia are also required for the pruning or addition of synapses. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm URL:http://www.neurolex.org/wiki/Category:Bergmann_Glial_Cell http://www.neurolex.org/wiki/Category:Bergmann_Glial_Cell Bergmann astrocyte Bergmann glial cell Bergmann glial cell of cerebellum cell FMA:54559 http://purl.org/obo/owl/FMA#FMA_54559 pituicyte A cell with long processes running parallel to adjacent axons in the proximal infundibulum of the neurohypophysis. These processes form a three-dimensional network among the axons of the hypothalamic neurosecretory cells and are connected by gap junctions which provide for their metabolic coupling. This cell type constitutes most of the nonexcitable tissue in the neurohypophsis; function may include possibly acting as an intermediate in the modulation of oxytocin and vasopressin release. This cell type is highly variable in size and shape and commonly contain lipid droplets and deposits of lipochrome pigment. ISBN:0412046911 http://purl.org/obo/owl/ISBN#ISBN_0412046911 ISBN:0517223651 http://purl.org/obo/owl/ISBN#ISBN_0517223651 URL:http://63.198.234.228/OpenFMA/Pituicyte.html http://63.198.234.228/OpenFMA/Pituicyte.html cell FMA:83503 http://purl.org/obo/owl/FMA#FMA_83503 BTO:0003793 http://purl.org/obo/owl/BTO#BTO_0003793 basal cell Undifferentiated; mitotic stem cell for other epithelial cell types; rounded or elliptical with little cytoplasm and few organelles; contain cytokeratin intermediate filament. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0517223651 http://purl.org/obo/owl/ISBN#ISBN_0517223651 URL:http://63.198.234.228/OpenFMA/Basal%20cell.html http://63.198.234.228/OpenFMA/Basal%20cell.html cell BTO:0000939 http://purl.org/obo/owl/BTO#BTO_0000939 FMA:62516 http://purl.org/obo/owl/FMA#FMA_62516 multinucleated giant cell Role or process: Chronic infection, granulomatous inflammation. Consider also megakaryocyte (CL:0000556) as sometimes multinucleated giant cell is used to refer to this. A phagocytic cell formed by the fusion of macrophages, occurs in chronic inflammatory responses to persistent microorganism such as M.tuberculosis, component of granulomas. Sometimes used to refer to megakaryocytes. GOC:add http://purl.org/obo/owl/GOC#GOC_add GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0702022918 http://purl.org/obo/owl/ISBN#ISBN_0702022918 ISBN:0702024783 http://purl.org/obo/owl/ISBN#ISBN_0702024783 Langerhans giant cell ISBN:0702022918 http://purl.org/obo/owl/ISBN#ISBN_0702022918 ISBN:0702024783 http://purl.org/obo/owl/ISBN#ISBN_0702024783 macrophage polykaryon ISBN:0702022918 http://purl.org/obo/owl/ISBN#ISBN_0702022918 ISBN:0702024783 http://purl.org/obo/owl/ISBN#ISBN_0702024783 multinucleate giant cell ISBN:0702022918 http://purl.org/obo/owl/ISBN#ISBN_0702022918 ISBN:0702024783 http://purl.org/obo/owl/ISBN#ISBN_0702024783 foreign body giant cell ISBN:0702022918 http://purl.org/obo/owl/ISBN#ISBN_0702022918 ISBN:0702024783 http://purl.org/obo/owl/ISBN#ISBN_0702024783 syncytial giant cell ISBN:0702022918 http://purl.org/obo/owl/ISBN#ISBN_0702022918 ISBN:0702024783 http://purl.org/obo/owl/ISBN#ISBN_0702024783 cell FMA:83035 http://purl.org/obo/owl/FMA#FMA_83035 BTO:0003107 http://purl.org/obo/owl/BTO#BTO_0003107 juxtaglomerular cell A smooth muscle cell that synthesizes, stores, and secretes the enzyme renin. This cell type are located in the wall of the afferent arteriole at the entrance to the glomerulus. While having a different origin than other kidney smooth muscle cells, this cell type expresses smooth muscle actin upon maturation. GOC:cvs http://purl.org/obo/owl/GOC#GOC_cvs GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm PMID:11457727 http://purl.org/obo/owl/PMID#PMID_11457727 renin secreting cell kidney granular cell JG cell cell CL:0000461 FMA:84138 http://purl.org/obo/owl/FMA#FMA_84138 prickle cell A cell with delicate radiating processes known as desmosomes that form intercellular bridges between other cells of this type. This cell type forms the stratum spinosum (prickle cell layer. A function of this cell is to generate keratin. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0721662544 http://purl.org/obo/owl/ISBN#ISBN_0721662544 ISBN:0815332181 http://purl.org/obo/owl/ISBN#ISBN_0815332181 prickle cell of epidermis cell CL:0002186 FMA:69059 http://purl.org/obo/owl/FMA#FMA_69059 mesangial cell A cell type that encapsulates the capillaries and venules in the kidney. This cell secretes mesangial matrix that provides the structural support for the capillaries. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm URL:http://www.copewithcytokines.de/cope.cgi?key=mesangial%20cells http://www.copewithcytokines.de/cope.cgi?key=mesangial%20cells cell BTO:0000853 http://purl.org/obo/owl/BTO#BTO_0000853 FMA:70972 http://purl.org/obo/owl/FMA#FMA_70972 neck cell A mucus-secreting cell, with numerous apical secretory vesicles containing mucins; nucleus are basally displaced; numerous at the neck of mucus secreting glands GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm mucous neck cell cell pinealocyte This cell type produces and secretes melatonin and forms the pineal parenchyma. Extending from each cell body, which has a spherical, oval or lobulated mucleus, are one or more tortuous basophilic processes, containing parallel microtubules known as synaptic ribbons. These processes end in expanded terminal buds near capillaries or less, frequently, ependymal cells of the pineal recess. The terminal buds contain granular endoplasmic reticulum, mitochondria and electron-dense cored vesicles, which store monoamines and polypeptide hormones, release of which appears to require sympathetic innervation. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0517223651 http://purl.org/obo/owl/ISBN#ISBN_0517223651 PMID:16687276 http://purl.org/obo/owl/PMID#PMID_16687276 URL:http://63.198.234.228/OpenFMA/Pinealocyte.html http://63.198.234.228/OpenFMA/Pinealocyte.html cell FMA:83417 http://purl.org/obo/owl/FMA#FMA_83417 BTO:0001068 http://purl.org/obo/owl/BTO#BTO_0001068 glomerular visceral epithelial cell GO has podocyte as a related synonym due to concern this may refer to more than one cell type. However, this did not turn up in my search. If podocyte does refer to more than one cell type, then we should classify the synonym to 'related'. A glomerular visceral epithelial cell is a specialized kidney epithelial cell that contains "feet" that interdigitate with the "feet" of other glomerular epithelial cells. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm podocyte cell BTO:0002295 http://purl.org/obo/owl/BTO#BTO_0002295 primary oocyte A primary oocyte is an oocyte that has not completed female meosis I. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0721662544 http://purl.org/obo/owl/ISBN#ISBN_0721662544 cell FMA:18645 http://purl.org/obo/owl/FMA#FMA_18645 BTO:0000512 http://purl.org/obo/owl/BTO#BTO_0000512 secondary oocyte A secondary oocyte is an oocyte that has not completed meiosis II. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0721662544 http://purl.org/obo/owl/ISBN#ISBN_0721662544 cell FMA:18646 http://purl.org/obo/owl/FMA#FMA_18646 BTO:0003094 http://purl.org/obo/owl/BTO#BTO_0003094 primary spermatocyte A diploid cell that has derived from a spermatogonium and can subsequently begin meiosis and divide into two haploid secondary spermatocytes. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0721662544 http://purl.org/obo/owl/ISBN#ISBN_0721662544 cell BTO:0001115 http://purl.org/obo/owl/BTO#BTO_0001115 FMA:72292 http://purl.org/obo/owl/FMA#FMA_72292 secondary spermatocyte One of the two haploid cells into which a primary spermatocyte divides, and which in turn gives origin to spermatids. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0721662544 http://purl.org/obo/owl/ISBN#ISBN_0721662544 cell FBbt:00004941 http://purl.org/obo/owl/FBbt#FBbt_00004941 BTO:0000709 http://purl.org/obo/owl/BTO#BTO_0000709 FMA:72293 http://purl.org/obo/owl/FMA#FMA_72293 cuticle secreting cell An epithelial cell that secretes cuticle. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm cell eggshell secreting cell An extracellular matrix secreting cell that secretes eggshell. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm cell glycocalyx secreting cell An extracellular matrix secreting cell that secretes glycocalyx. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm cell distal tip cell (sensu Nematoda) cell neuroglioblast (sensu Nematoda) cell valve cell cell closable valve cell cell permanently open valve cell cell fenestrated cell window cell cell collagen secreting cell An extracellular matrix secreting cell that secretes collagen. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm cell parenchymal cell cell type has a similar but slightly different meaning in botany (plants): see PO:0000074. The cell characteristic of an organ, as distinguished from associated connective or supporting tissues. ISBN:0471245208 http://purl.org/obo/owl/ISBN#ISBN_0471245208 cell BTO:0002174 http://purl.org/obo/owl/BTO#BTO_0002174 FMA:84638 http://purl.org/obo/owl/FMA#FMA_84638 pericyte cell Pericytes are CD10-positive, CD13-positive, CD31-negative, CD45-negative, CD106-positive, CD117-negative, CD140-positive, CD144-negative, CD146-positive, CD271-positive, CD325-positive, NG2-positive, RGS5-positive, SMA-positive, and desmin-positive. A subpopulation is CD248-positive. They are also capable of producing angiopoietin 1, CXCL12, TGF-beta, and VEGF-A. An elongated, contractile cell found wrapped about precapillary arterioles outside the basement membrane. Pericytes are present in capillaries where proper adventitia and muscle layer are missing (thus distingushing this cell type from adventitial cells). They are relatively undifferentiated and may become fibroblasts, macrophages, or smooth muscle cells. GOC:dsd http://purl.org/obo/owl/GOC#GOC_dsd GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0721662544 http://purl.org/obo/owl/ISBN#ISBN_0721662544 MESH:D020286 http://purl.org/obo/owl/MESH#MESH_D020286 PMID:16807374 http://purl.org/obo/owl/PMID#PMID_16807374 PMID:17986482 http://purl.org/obo/owl/PMID#PMID_17986482 PMID:20024907 http://purl.org/obo/owl/PMID#PMID_20024907 pericyte adventitial reticular cell Cell of Rouget adventitial cell Pericyte of Rouget ARC PMID:17986482 http://purl.org/obo/owl/PMID#PMID_17986482 cell CL:0000184 FMA:63174 http://purl.org/obo/owl/FMA#FMA_63174 BTO:0002441 http://purl.org/obo/owl/BTO#BTO_0002441 primordial germ cell A primordial germ cell is a diploid germ cell precursors that transiently exist in the embryo before they enter into close association with the somatic cells of the gonad and become irreversibly committed as germ cells. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm PMID:1381289 http://purl.org/obo/owl/PMID#PMID_1381289 Gonocyte Primitive germ cell cell FMA:70567 http://purl.org/obo/owl/FMA#FMA_70567 centripetally migrating follicle cell cell FBbt:00004906 http://purl.org/obo/owl/FBbt#FBbt_00004906 tracheary element replaced_by: PO:0000290 Obsolete. Use PO:0000290 from Plant Ontology instead. A water conducting cell, tracheid or vessel member. ISBN:0471245208 http://purl.org/obo/owl/ISBN#ISBN_0471245208 cell Kenyon cell cell interfollicle cell fly stalk cell cell FBbt:00004910 http://purl.org/obo/owl/FBbt#FBbt_00004910 female gamete A mature sexual reproductive cell of the female germline. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm cell cap cell cell BTO:0001033 http://purl.org/obo/owl/BTO#BTO_0001033 gut absorptive cell Cell of the intestinal epithelium with a brush border made up of many parallel packed microvilli; associated with absorption, particularly of macromolecules. JB:jb http://purl.org/obo/owl/JB#JB_jb cell commisural neuron cell glutamatergic neuron cell muscle precursor cell cell radial glial cell A transient cell present only in the developing CNS. Functions as both a precursor cell and as a scaffold to support neuronal migration. GOC:dph http://purl.org/obo/owl/GOC#GOC_dph cell M cell An absorptive cell of the gut epithelium that endocytoses microorganisms and intact macromolecules from the gut lumen and transports them to the subepithelial space where they are presented to antigen-presenting cells and lymphocytes. GOC:jb http://purl.org/obo/owl/GOC#GOC_jb GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm microfold cell M-cell cell FMA:62929 http://purl.org/obo/owl/FMA#FMA_62929 BTO:0003600 http://purl.org/obo/owl/BTO#BTO_0003600 ependymoglial cell A cell that transports hormones from neurosecretory cells. This nerve cell is characterized by bipolar shape and endfeet that contact a basal lamina around blood vessels, and/or the pia mater or vitreous body of the eye and additionally contact the ventricular surface or sub-retinal space. JB:jb http://purl.org/obo/owl/JB#JB_jb URL:http://neurolex.org/wiki/Category:Ependymoglial_Cell http://neurolex.org/wiki/Category:Ependymoglial_Cell Ependymal astrocyte cell littoral cell of liver cell meristematic cell replaced_by: PO:0004010 Obsolete. Use PO:0004010 from Plant Ontology instead. A cell synthesizing protoplasm and producing new cells by division and with only a primary cell wall. PO:0004010 http://purl.org/obo/owl/PO#PO_0004010 cell cerebrospinal fluid secreting cell A columnar/cuboidal epithelial cell that secretes cerebrospinal fluid. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm cell R1 photoreceptor cell cell perijunctional fibroblast A fibroblast-like cell that provides support at neuromuscular junctions in vertebrates and are localized outside the synaptic basal lamina. JB:jb http://purl.org/obo/owl/JB#JB_jb cell myoendocrine cell A cell with both myofibrils and secretory granules. JB:jb http://purl.org/obo/owl/JB#JB_jb cell R2 photoreceptor cell cell stellate interneuron cell terminal Schwann cell A neuroglial cell of the peripheral nervous system inside the basal lamina of the neuromuscular junction providing chemical and physical support to the synapse. JB:jb http://purl.org/obo/owl/JB#JB_jb PMID:16136171 http://purl.org/obo/owl/PMID#PMID_16136171 Schwann cell cell neuroglioform cell A stellate interneuron having 7-10 dendrites that may branch. JB:jb http://purl.org/obo/owl/JB#JB_jb spiderweb cell cell R3 photoreceptor cell cell Cajal-Retzius cell One of a transient population of pioneering neurons in the cerebral cortex. These cells are slender bipolar cells of the developing marginal zone. One feature of these cells in mammals is that they express the Reelin gene. PMID:10600995 http://purl.org/obo/owl/PMID#PMID_10600995 PMID:9728912 http://purl.org/obo/owl/PMID#PMID_9728912 cell PP cell A cell that stores and secretes pancreatic polypeptides. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm JB:jb http://purl.org/obo/owl/JB#JB_jb PMID:15153415 http://purl.org/obo/owl/PMID#PMID_15153415 Type F enteroendocrine cell cell FMA:62938 http://purl.org/obo/owl/FMA#FMA_62938 FMA:83409 http://purl.org/obo/owl/FMA#FMA_83409 R4 photoreceptor cell cell paraganglial cell cell paraganglial type 1 cell A type of glomus or chief cell, is sensitive to hypoxia and produce catecholamines. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm cell dopaminergic neuron A neuron that releases dopamine as a neurotransmitter. GOC:dhill http://purl.org/obo/owl/GOC#GOC_dhill Dopaminergic cell cell FMA:84787 http://purl.org/obo/owl/FMA#FMA_84787 BTO:0004032 http://purl.org/obo/owl/BTO#BTO_0004032 paraganglia type 2 cell Supports paraganglial type 1 cell. JB:jb http://purl.org/obo/owl/JB#JB_jb cell R5 photoreceptor cell cell sustentacular cell Cell that provides some or all mechanical, nutritional and phagocytic support to their neighbors. JB:jb http://purl.org/obo/owl/JB#JB_jb cell BTO:0002315 http://purl.org/obo/owl/BTO#BTO_0002315 endothelial tip cell A specialized endothelial cell that senses extracellular signals and guides the directed growth of blood vessels. PMID:15376331 http://purl.org/obo/owl/PMID#PMID_15376331 cell R6 photoreceptor cell cell choroid plexus epithelial cell Specialized ependymal cell that produces the cerebrospinal fluid from the blood and secretes it into the lumen of the brain and spinal chord. GOC:add http://purl.org/obo/owl/GOC#GOC_add GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm JB:jb http://purl.org/obo/owl/JB#JB_jb PMID:9550134 http://purl.org/obo/owl/PMID#PMID_9550134 epithelial cell of choroid plexus cell CL:1000430 FMA:70549 http://purl.org/obo/owl/FMA#FMA_70549 R7 photoreceptor cell cell leptomeningeal cell Stromal cell that forms the internal covering of the vertebrate brain and produces ECM for this and the choroid plexus. JB:jb http://purl.org/obo/owl/JB#JB_jb leptomemingeal cell cell R8 photoreceptor cell cell neurecto-epithelial cell The term "neuroepithelial cell" is used to describe both this cell type and sensory epithelial cell (CL:0000098). Epithelial cells derived from neural plate and neural crest. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm URL:http://63.198.234.228/OpenFMA/Neurecto-epithelial%20cell.html http://63.198.234.228/OpenFMA/Neurecto-epithelial%20cell.html neuroepithelial cell cell FMA:70557 http://purl.org/obo/owl/FMA#FMA_70557 BTO:0004301 http://purl.org/obo/owl/BTO#BTO_0004301 cumulus cell Cumulus cell is a specialized granulosa cell that surrounds and nourishes the oocyte. This cell-type surrounds the fully-grown oocyte to form a cumulus-oocyte complex (abbr. COC). The terms cumulus oophorus cells, cumulus granulosa cells, cumulus oophorous granulosa cells, granulosa-cumulus cells are used to make a distinction between this cell and the other functionally different subpopulation of granulosa cells at the wall of the Graafian follicle. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm URL:http://www.copewithcytokines.org/cope.cgi?key=cumulus%20cells http://www.copewithcytokines.org/cope.cgi?key=cumulus%20cells cell BTO:0002236 http://purl.org/obo/owl/BTO#BTO_0002236 stratum granulosum cell cell corona radiata cell cell embryonic crystal cell cell lymph gland crystal cell cell fusimotor neuron A subset of motor neurons that innervates intrafusal muscle fibers and has small diameter axons. PMID:15582775 http://purl.org/obo/owl/PMID#PMID_15582775 cell cone cell (sensu Endopterygota) cell posterior cone cell (sensu Endopterygota) cell anterior cone cell (sensu Endopterygota) cell equatorial cone cell (sensu Endopterygota) cell cystoblast cell somatic stem cell A stem cell that can give rise to cell types of the body other than those of the germ-line. GO:0048103 http://purl.org/obo/owl/GO#GO_0048103 cell FMA:63368 http://purl.org/obo/owl/FMA#FMA_63368 heterocyst A differentiated cell that functions as a site of nitrogen fixation under aerobic conditions. MA:ma http://purl.org/obo/owl/MA#MA_ma cell BTO:0000600 http://purl.org/obo/owl/BTO#BTO_0000600 nitrogen fixing cell cell chlamydospore Considering obsoleting as sometimes used to refer to protozoans too. But reference indicates term was intended for fungus. An asexual 1-celled spore (primarily for perennation, not dissemination). Originates endogenously and singly within part of a pre-existing cell by the contraction of the protoplast. Possesses an inner secondary and often thickened hyaline or brown wall, usually impregnated with hydrophobic material. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:085199377X http://purl.org/obo/owl/ISBN#ISBN_085199377X cell primary pigment cell cell secondary pigment cell cell tertiary pigment cell cell leading edge cell A cell at the front of a migrating epithelial sheet. MA:ma http://purl.org/obo/owl/MA#MA_ma cell urothelial cell A cell of a layer of transitional epithelium in the wall of the bladder, ureter, and renal pelvis, external to the lamina propria. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm MA:ma http://purl.org/obo/owl/MA#MA_ma Bladder transitional cell Urinary tract transitional epithelial cell Transitional epithelial cell of urinary bladder cell FMA:84127 http://purl.org/obo/owl/FMA#FMA_84127 amoeboid cell cell lymph gland plasmatocyte cell embryonic gland plasmatocyte cell lymph gland hemocyte cell embryonic gland hemocyte cell striated muscle cell Muscle cell which has as its direct parts myofilaments organized into sarcomeres. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0721662544 http://purl.org/obo/owl/ISBN#ISBN_0721662544 cell BTO:0002916 http://purl.org/obo/owl/BTO#BTO_0002916 FMA:86936 http://purl.org/obo/owl/FMA#FMA_86936 leukocyte An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue. GOC:add http://purl.org/obo/owl/GOC#GOC_add GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:978-0-323-05290-0 http://purl.org/obo/owl/ISBN#ISBN_978-0-323-05290-0 immune cell leucocyte white blood cell cell BTO:0000751 http://purl.org/obo/owl/BTO#BTO_0000751 FMA:62852 http://purl.org/obo/owl/FMA#FMA_62852 retinal ganglion cell The set of neurons that receives neural inputs via bipolar, horizontal and amacrine cells. The axons of these cells make up the optic nerve. GOC:dph http://purl.org/obo/owl/GOC#GOC_dph ganglion cell of retina gangliocyte RGC cell BTO:0001800 http://purl.org/obo/owl/BTO#BTO_0001800 FMA:67765 http://purl.org/obo/owl/FMA#FMA_67765 spinal accessory motor neuron A motor neuron that is located in the cervical region of the spinal cord and selectively innervates the sternocleidmastoid or trapezius muscle. Unlike other motor neurons, they extend axons dorsally along lateral margins of the spinal cord. PMID:16267219 http://purl.org/obo/owl/PMID#PMID_16267219 SACMN cell periarticular chondrocyte A round chondrocyte that first differentiates in the late embryonic growth plate of bone. PMID:15951842 http://purl.org/obo/owl/PMID#PMID_15951842 cell hypertrophic chondrocyte A terminally differentiated chondrocyte that differentiates in the late embryonic growth plate of bone. PMID:15951842 http://purl.org/obo/owl/PMID#PMID_15951842 cell columnar chondrocyte A columnar chondrocyte that differentiates in the late embryonic growth plate of bone. Columnar chondrocytes vigorously proliferate and form columns in the growth plate. PMID:15951842 http://purl.org/obo/owl/PMID#PMID_15951842 cell horizontal cell A neuron that laterally connects other neurons in the inner nuclear layer of the retina. ISBN:0195088433 http://purl.org/obo/owl/ISBN#ISBN_0195088433 cell BTO:0004120 http://purl.org/obo/owl/BTO#BTO_0004120 cardiac muscle cell A myocyte located in the heart. The contractile fiber resembles those of skeletal muscle but are only one third as large in diameter, are richer in sarcoplasm, and contain centrally located instead of peripheral nuclei. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0323052908 http://purl.org/obo/owl/ISBN#ISBN_0323052908 cardiocyte cardiac myocyte heart muscle cell cardiomyocyte cell FMA:83808 http://purl.org/obo/owl/FMA#FMA_83808 BTO:0001539 http://purl.org/obo/owl/BTO#BTO_0001539 FMA:14067 http://purl.org/obo/owl/FMA#FMA_14067 cyanophore A pigment cell derived from the neural crest. Contains blue pigment of unknown chemical composition in fibrous organelles termed cyanosomes. This gives a blue appearance. SANBI:mhl http://purl.org/obo/owl/SANBI#SANBI_mhl blue chromatophore cell retinal bipolar neuron A bipolar neuron found in the retina and having connections with photoreceptors cells and neurons in the inner plexiform layer. PMID:14689473 http://purl.org/obo/owl/PMID#PMID_14689473 cell ON-bipolar cell A bipolar neuron found in the retina and having connections with photoreceptors cells and neurons in the inner half of the inner plexiform layer. These cells depolarize in response to light stimulation of their corresponding photoreceptors. PMID:14689473 http://purl.org/obo/owl/PMID#PMID_14689473 cell OFF-bipolar cell A bipolar neuron found in the retina and having connections with photoreceptors cells and neurons in the outer half of the inner plexiform layer. These cells hyperpolarize in response to light stimulation of their corresponding photoreceptors. PMID:14689473 http://purl.org/obo/owl/PMID#PMID_14689473 cell rod bipolar cell A bipolar neuron found in the retina and having connections with rod photoreceptor cells and neurons in the inner plexiform layer. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm PMID:14689473 http://purl.org/obo/owl/PMID#PMID_14689473 cell FMA:67750 http://purl.org/obo/owl/FMA#FMA_67750 cone retinal bipolar cell A bipolar neuron found in the retina and having connections with cone photoreceptor cells and neurons in the inner plexiform layer. PMID:14689473 http://purl.org/obo/owl/PMID#PMID_14689473 cell type 1 cone bipolar cell (sensu Mus) An OFF-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the outer half of the inner plexiform layer. The cell body of these cells is in the middle of the inner plexiform layer. The dendritic tree is stout and the axon terminates in sublamina 1. The axonal terminal is wide and has only a few varicosities. PMID:14689473 http://purl.org/obo/owl/PMID#PMID_14689473 DB1 cone bipolar cell cell type 2 cone bipolar cell (sensu Mus) An OFF-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the outer half of the inner plexiform layer. The dendritic tree is not well filled and the dendrites are more delicate than in type 1 cells. The axon terminal is bushier and exhibits a dense plexus of varicosities in the inner part of sublamina 1. PMID:14689473 http://purl.org/obo/owl/PMID#PMID_14689473 FMB cone bipolar cell cell type 3 cone bipolar cell (sensu Mus) An OFF-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the outer half of the inner plexiform layer. The dendritic tree is delicate and the dendritic tips appear small when compared with type 1 cells. The axon terminal is stratified and restricted to sublamina 2 of the inner plexiform layer. PMID:14689473 http://purl.org/obo/owl/PMID#PMID_14689473 DB2 cone bipolar cell cell type 4 cone bipolar cell (sensu Mus) An OFF-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the outer half of the inner plexiform layer. The cell has a diffuse axon terminal with varicosities in sublaminae 1 and 2 of the inner plexiform layer. PMID:14689473 http://purl.org/obo/owl/PMID#PMID_14689473 DB3 cone bipolar cell cell type 5 cone bipolar cell (sensu Mus) An ON-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the inner half of the inner plexiform layer. The axon terminal is restricted to sublamina 3 of the inner plexiform layer. It is narrowly stratified and branched. The dendritic tree has many delicate branches. PMID:14689473 http://purl.org/obo/owl/PMID#PMID_14689473 DB4 cone bipolar cell cell type 6 cone bipolar cell (sensu Mus) An ON-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the inner half of the inner plexiform layer. The cell has a loose, delicate axon terminal that opens in sublamina 3 of the inner plexiform layer and descends into sublamina 4. PMID:14689473 http://purl.org/obo/owl/PMID#PMID_14689473 DB5 cone bipolar cell cell type 7 cone bipolar cell (sensu Mus) An ON-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the inner half of the inner plexiform layer. The axon terminal is narrowly stratified and are found just below a calretinin-expressing band in sublamina 4 of the inner plexiform layer. PMID:14689473 http://purl.org/obo/owl/PMID#PMID_14689473 IMB cone bipolar cell cell type 8 cone bipolar cell (sensu Mus) An ON-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the inner half of the inner plexiform layer. This cell has the widest dendritic field and the widest axon terminal of all retinal bipolar cells. The axon terminal is delicate and stratified through sublaminae 4 and 5 of the inner plexiform layer. PMID:14689473 http://purl.org/obo/owl/PMID#PMID_14689473 DB6 cone bipolar cell cell type 9 cone bipolar cell (sensu Mus) An ON-bipolar neuron found in the retina and having connections with cone photoreceptors cells and neurons in the inner half of the inner plexiform layer. The dendritic tree is wide and the dendritic convergence indicates cone selectivity. The axon terminal is sparsely branched and terminates in sublamina 5 of the inner plexiform layer. PMID:14689473 http://purl.org/obo/owl/PMID#PMID_14689473 BB cone bipolar cell cell nucleated thrombocyte Note that this is a non-mammalian cell type. Use platelet ; CL:0000233 for thrombocytes (platelets) in mammals. A nucleated blood cell involved in coagulation, typically seen in birds and other non-mammalian vertebrates. GOC:add http://purl.org/obo/owl/GOC#GOC_add GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm PMID:16360205 http://purl.org/obo/owl/PMID#PMID_16360205 cell myeloid cell A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage. GOC:add http://purl.org/obo/owl/GOC#GOC_add cell BTO:0001441 http://purl.org/obo/owl/BTO#BTO_0001441 erythroid lineage cell NOTE: in FMA erythropoeitic cells are types of nucleated erythrocytes and thus don't include erythrocytes. A immature or mature cell in the lineage leading to and including erythrocytes. GOC:add http://purl.org/obo/owl/GOC#GOC_add GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm erythropoietic cell cell CL:0002156 FMA:62845 http://purl.org/obo/owl/FMA#FMA_62845 FMA:83516 http://purl.org/obo/owl/FMA#FMA_83516 erythroblast A nucleated precursor of an erythrocyte that lacks hematopoietic lineage markers. GOC:add http://purl.org/obo/owl/GOC#GOC_add ISBN:0721601464 http://purl.org/obo/owl/ISBN#ISBN_0721601464 PMID:18174176 http://purl.org/obo/owl/PMID#PMID_18174176 normoblast cell BTO:0001571 http://purl.org/obo/owl/BTO#BTO_0001571 FMA:83504 http://purl.org/obo/owl/FMA#FMA_83504 myeloid leukocyte A cell of the monocyte, granulocyte, or mast cell lineage. GOC:add http://purl.org/obo/owl/GOC#GOC_add cell basophil Matures in the bone marrow and account for <1% of leukocytes in the peripheral blood, spleen, and bone marrow. Basophils are described as being CD11a-positive, CD11b-positive, CD13-positive, CD15-positive, CD18-positive, CD21-positive, CD25-positive, CD29-positive, CD35-positive, CD40-positive, CD40L-positive, CD44-positive, CD45R-negative, CD46-positive, CD49a-positive, CD49b-positive, CD49d-positive, CD55-positive, CD59-positive, CD62L-positive, CD63-positive, CD69-positive, CD90-negative, CD116-positive, CD117-negative, CD124-positive, CD125-positive, CD131-positive, CD161-positive, CD184-positive, CD191-positive, CD192-positive, CD197-positive, CD200R3-positive, CD218-positive, CD282-positive, CD284-positive, CD289-positive, CD290-positive, CD294-positive, natural killer cell receptor 2B4-positive, smad1-positive, CD3-negative, CD4-negative, CD7-negative, CD8-negative, CD14-negative, CD15-negative, CD16-negative, CD19-negative, CD20-negative, CD34-negative, CD36-negative, CD45R-negative, CD56-negative, CD57-negative, CD235a-negative, and GR1-negative. Transcription factors- GATA1-positive, PU.1-positive. Any of the immature or mature forms of a granular leukocyte that in its mature form has an irregularly shaped, pale-staining nucleus that is partially constricted into two lobes, and with cytoplasm that contains coarse, bluish-black granules of variable size. Basophils contain vasoactive amines such as histamine and serotonin, which are released on appropriate stimulation. A basophil is CD123-positive, CD193-positive, CD203c-positive, and FceRIa-positive. GOC:add http://purl.org/obo/owl/GOC#GOC_add GOC:amm http://purl.org/obo/owl/GOC#GOC_amm GOC:dsd http://purl.org/obo/owl/GOC#GOC_dsd GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0721601464 http://purl.org/obo/owl/ISBN#ISBN_0721601464 MESH:D001491 http://purl.org/obo/owl/MESH#MESH_D001491 PMCID:PMC2626675 http://purl.org/obo/owl/PMCID#PMCID_PMC2626675 PMID:11927641 http://purl.org/obo/owl/PMID#PMID_11927641 PMID:19741522 http://purl.org/obo/owl/PMID#PMID_19741522 PMID:21236338 http://purl.org/obo/owl/PMID#PMID_21236338 PMID:9933081 http://purl.org/obo/owl/PMID#PMID_9933081 polymorphonuclear leukocyte basophilic leukocyte basophilic leucocyte polymorphonuclear leucocyte cell BTO:0000129 http://purl.org/obo/owl/BTO#BTO_0000129 FMA:62862 http://purl.org/obo/owl/FMA#FMA_62862 immature basophil Any of the immature forms of a basophil, in which basophilic specific granules are present but other phenotypic features of the mature form may be lacking. GOC:add http://purl.org/obo/owl/GOC#GOC_add ISBN:0721601464 http://purl.org/obo/owl/ISBN#ISBN_0721601464 immature basophilic leucocyte immature basophilic leukocyte cell basophilic metamyelocyte A basophil precursor in the granulocytic series, being a cell intermediate in development between a basophilic myelocyte and a band form basophil. The nucleus becomes indented where the indentation is smaller than half the distance to the farthest nuclear margin; chromatin becomes coarse and clumped; specific granules predominate while primary granules are rare. Markers are CD11b-positive, CD15-positive, CD16-positive, CD24-positive, CD33-positive, and CD13-positive. GOC:tfm http://purl.org/obo/owl/GOC#GOC_tfm ISBN:0721601464 http://purl.org/obo/owl/ISBN#ISBN_0721601464 PMID:18466030 http://purl.org/obo/owl/PMID#PMID_18466030 cell FMA:84198 http://purl.org/obo/owl/FMA#FMA_84198 band form basophil A late basophilic metamyelocyte in which the nucleus is in the form of a curved or coiled band, not having acquired the typical multilobar shape of the mature basophil. GOC:add http://purl.org/obo/owl/GOC#GOC_add