obo-all/biological_process/biological_process.obo file obo-all/biological_process/biological_process.obo biological_process.obo 816c4ba13abaea0da8144f519415bd73 1214339045 1214339046

1.2 24:06:2008 13:22 /usr/bin/go2fmt.pl 1.2 23:06:2008 11:12 tanyaberardini OBO-Edit 1.101 gene_ontology cvs version: $Revision: 1.224 $ systematic_synonym Systematic synonym EXACT goslim_candida Candida GO slim goslim_generic Generic GO slim goslim_goa GOA and proteome slim goslim_pir PIR GO slim goslim_plant Plant GO slim goslim_yeast Yeast GO slim gosubset_prok Prokaryotic GO subset

GO:0000001 mitochondrion inheritance biological_process The distribution of mitochondria, including the mitochondrial genome, into daughter cells after mitosis or meiosis, mediated by interactions between mitochondria and the cytoskeleton. mcc GOC 10873824 PMID 11389764 PMID GO:0048308 GO:0048311 mitochondrial inheritance GO:0000002 mitochondrial genome maintenance biological_process The maintenance of the structure and integrity of the mitochondrial genome; includes replication and segregation of the mitochondrial chromosome. ai GOC vw GOC GO:0007005 GO:0000003 reproduction GO:0019952 GO:0050876 biological_process The production by an organism of new individuals that contain some portion of their genetic material inherited from that organism. go_curators GOC isa_complete GOC 0198506732 ISBN Oxford Dictionary of Biochemistry and Molecular Biology goslim_generic goslim_pir goslim_plant gosubset_prok GO:0008150 reproductive physiological process GO:0000011 vacuole inheritance biological_process The distribution of vacuoles into daughter cells after mitosis or meiosis, mediated by interactions between vacuoles and the cytoskeleton. mcc GOC 10873824 PMID 14616069 PMID GO:0007033 GO:0048308 GO:0000012 single strand break repair biological_process The repair of single strand breaks in DNA. Repair of such breaks is mediated by the same enzyme systems as are used in base excision repair. http://www.ultranet.com/~jkimball/BiologyPages/D/DNArepair.html URL gosubset_prok GO:0006281 GO:0000017 alpha-glucoside transport biological_process The directed movement of alpha-glucosides into, out of, within or between cells. Alpha-glucosides are glycosides in which the sugar moiety is a glucose residue, and the anomeric carbon of the bond is in an alpha configuration. jl GOC http://www.biochem.purdue.edu/ URL 0198506732 ISBN Oxford Dictionary of Biochemistry and Molecular Biology GO:0042946 GO:0000018 regulation of DNA recombination biological_process Any process that modulates the frequency, rate or extent of DNA recombination, a process by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. go_curators GOC 0198506732 ISBN Oxford Dictionary of Biochemistry and Molecular Biology gosubset_prok GO:0051052 regulates GO:0006310 GO:0000019 regulation of mitotic recombination biological_process Any process that modulates the frequency, rate or extent of DNA recombination during mitosis. go_curators GOC GO:0000018 regulates GO:0006312 regulation of recombination within rDNA repeats GO:0000020 negative regulation of recombination within rDNA repeats biological_process OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of genetic recombination within the DNA of the genes coding for ribosomal RNA. go_curators GOC 0198506732 ISBN Oxford Dictionary of Biochemistry and Molecular Biology This term was made obsolete because it describes a substrate-specific process. 1 GO:0045950 GO:0000022 mitotic spindle elongation biological_process Lengthening of the distance between poles of the mitotic spindle. mah GOC GO:0051231 OBO_REL:part_of GO:0007052 spindle elongation during mitosis GO:0000023 maltose metabolic process biological_process The chemical reactions and pathways involving the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose), an intermediate in the catabolism of glycogen and starch. jl GOC 0198506732 ISBN Oxford Dictionary of Biochemistry and Molecular Biology gosubset_prok GO:0005984 malt sugar metabolic process malt sugar metabolism maltose metabolism GO:0000024 maltose biosynthetic process biological_process The chemical reactions and pathways resulting in the formation of the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose). jl GOC 0198506732 ISBN Oxford Dictionary of Biochemistry and Molecular Biology gosubset_prok GO:0000023 GO:0046351 malt sugar biosynthesis malt sugar biosynthetic process maltose anabolism maltose biosynthesis maltose formation maltose synthesis GO:0000025 maltose catabolic process biological_process The chemical reactions and pathways resulting in the breakdown of the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose). jl GOC 0198506732 ISBN Oxford Dictionary of Biochemistry and Molecular Biology gosubset_prok GO:0000023 GO:0046352 malt sugar catabolic process malt sugar catabolism maltose breakdown maltose degradation maltose hydrolysis MALTOSECAT-PWY MetaCyc GO:0000027 ribosomal large subunit assembly and maintenance biological_process The aggregation, arrangement and bonding together of constituent RNAs and proteins to form and maintain the large ribosomal subunit. jl GOC gosubset_prok GO:0042257 OBO_REL:part_of GO:0042273 GO:0000028 ribosomal small subunit assembly and maintenance biological_process The aggregation, arrangement and bonding together of constituent RNAs and proteins to form and maintain the small ribosomal subunit. jl GOC gosubset_prok GO:0042257 OBO_REL:part_of GO:0042274 GO:0000032 cell wall mannoprotein biosynthetic process biological_process The chemical reactions and pathways resulting in the formation of cell wall mannoproteins, any cell wall protein that contains covalently bound mannose residues other than as a moiety of nucleic acid. ai GOC gosubset_prok GO:0006057 GO:0031506 cell wall mannoprotein anabolism cell wall mannoprotein biosynthesis cell wall mannoprotein formation cell wall mannoprotein synthesis GO:0000038 very-long-chain fatty acid metabolic process biological_process The chemical reactions and pathways involving fatty acids with a chain length of C18 or greater. hjd GOC gosubset_prok GO:0006631 very-long-chain fatty acid metabolism GO:0000040 low-affinity iron ion transport biological_process The directed, low-affinity movement of iron (Fe) ions into, out of, within or between cells. In low affinity transport the transporter is able to bind the solute only if it is only present at very low concentrations. mah GOC GO:0006826 GO:0034220 low affinity iron ion transport GO:0000041 transition metal ion transport biological_process The directed movement of transition metal ions into, out of, within or between cells. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver. 0198506732 ISBN Oxford Dictionary of Biochemistry and Molecular Biology gosubset_prok GO:0030001 transition metal transport GO:0000042 protein targeting to Golgi biological_process The process of directing proteins towards the Golgi using signals contained within the protein. ai GOC GO:0000301 GO:0006605 protein-Golgi targeting GO:0000044 ascorbate stabilization biological_process OBSOLETE. The reduction of the ascorbate free radical to a stable form. ai GOC mtg_electron_transport GOC This term was made obsolete because it is defined as a function term and is in the process ontology. vitamin C stabilization 1 GO:0000045 autophagic vacuole formation biological_process The formation of a double membrane-bounded structure, the autophagosome, that occurs when a specialized membrane sac, called the isolation membrane, starts to enclose a portion of the cytoplasm. 9412464 PMID GO:0016050 OBO_REL:part_of GO:0016236 autophagosome biosynthesis autophagosome formation PAS formation GO:0000046 autophagic vacuole fusion biological_process The fusion of an autophagic vacuole with a vacuole (yeast) or lysosome (e.g. mammals and insects). In the case of yeast, inner membrane-bounded structures (autophagic bodies) appear in the vacuole. 11099404 PMID GO:0006944 GO:0048284 OBO_REL:part_of GO:0016236 fusion of autophagosome with lysosome GO:0000050 urea cycle GO:0006594 GO:0006871 biological_process A cyclic metabolic pathway that converts waste nitrogen in the form of ammonium to urea. 0198506732 ISBN Oxford Dictionary of Biochemistry and Molecular Biology GO:0019627 ornithine cycle urea biosynthesis urea biosynthetic process 211547 Reactome 221324 Reactome 229964 Reactome 237981 Reactome 244600 Reactome 249543 Reactome 252354 Reactome 255509 Reactome 258881 Reactome 262258 Reactome 265108 Reactome 268232 Reactome 273914 Reactome 280393 Reactome 282778 Reactome 286409 Reactome 288203 Reactome 289764 Reactome 290323 Reactome 291648 Reactome 292335 Reactome 293622 Reactome 70635 Reactome GO:0000051 urea cycle intermediate metabolic process biological_process The chemical reactions and pathways involving any of the intermediate compounds involved in the urea cycle, a cyclic metabolic pathway that converts waste nitrogen in the form of ammonium to urea. jl GOC 0198506732 ISBN Oxford Dictionary of Biochemistry and Molecular Biology gosubset_prok GO:0008152 OBO_REL:part_of GO:0006807 urea cycle intermediate metabolism GO:0000052 citrulline metabolic process biological_process The chemical reactions and pathways involving citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins. 0198506732 ISBN Oxford Dictionary of Biochemistry and Molecular Biology gosubset_prok GO:0000051 GO:0019794 citrulline metabolism GO:0000053 argininosuccinate metabolic process biological_process The chemical reactions and pathways involving argininosuccinate, 2-(Nw-arginino)succinate, an intermediate in the ornithine-urea cycle, where it is synthesized from citrulline and aspartate. 0198506732 ISBN Oxford Dictionary of Biochemistry and Molecular Biology GO:0000051 argininosuccinate metabolism GO:0000054 ribosome export from nucleus biological_process The directed movement of a ribosome from the nucleus into the cytoplasm. ai GOC GO:0033753 GO:0051168 OBO_REL:part_of GO:0042254 ribosome export out of nucleus ribosome transport from nucleus to cytoplasm ribosome-nucleus export GO:0000055 ribosomal large subunit export from nucleus GO:0000057 biological_process The directed movement of a ribosomal large subunit from the nucleus into the cytoplasm. mah GOC GO:0000054 ribosomal large subunit export out of nucleus ribosomal large subunit transport from nucleus to cytoplasm ribosomal large subunit-nucleus export GO:0000056 ribosomal small subunit export from nucleus GO:0000058 biological_process The directed movement of a ribosomal small subunit from the nucleus into the cytoplasm. mah GOC GO:0000054 ribosomal small subunit export out of nucleus ribosomal small subunit transport from nucleus to cytoplasm ribosomal small subunit-nucleus export GO:0000059 protein import into nucleus, docking biological_process The aggregation, arrangement and bonding together of the nuclear localization signal of a protein with nuclear envelope proteins such as importins. isa_complete GOC 7878057 PMID GO:0043623 OBO_REL:part_of GO:0006606 protein docking during protein import into nucleus protein docking during protein transport from cytoplasm to nucleus protein docking during protein-nucleus import protein transport from cytoplasm to nucleus, docking protein-nucleus import, docking GO:0000060 protein import into nucleus, translocation biological_process The vectorial transfer of a protein from the cytoplasm into the nucleus, through the nuclear pore and across the nuclear envelope. jl GOC vw GOC 0198506732 ISBN Oxford Dictionary of Biochemistry and Molecular Biology GO:0006886 OBO_REL:part_of GO:0006606 protein translocation during protein import into nucleus protein translocation during protein transport from cytoplasm to nucleus protein translocation during protein-nucleus import protein transport from cytoplasm to nucleus, translocation protein-nucleus import, translocation GO:0000061 protein import into nucleus, substrate release biological_process The disaggregation of a protein complex composed of the nuclear localization sequence and the importin alpha, and importin beta proteins. 9687515 PMID GO:0043624 OBO_REL:part_of GO:0006606 protein substrate release during protein import into nucleus protein substrate release during protein transport from cytoplasm to nucleus protein substrate release during protein-nucleus import protein transport from cytoplasm to nucleus, substrate release protein-nucleus import, substrate release GO:0000066 mitochondrial ornithine transport biological_process The directed movement of ornithine, 2,5-diaminopentanoic acid, into, out of or within a mitochondrion. ai GOC GO:0006839 GO:0015822 GO:0000067 DNA replication and chromosome cycle biological_process OBSOLETE (was not defined before being made obsolete). ai GOC This term was made obsolete because it has been superseded by more accurate terms to represent the biological processes occurring, and it is not clear that this term represents a useful concept. 1 GO:0006260 GO:0007059 GO:0051276 GO:0000070 mitotic sister chromatid segregation GO:0016359 biological_process The cell cycle process whereby replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets. ai GOC GO:0000819 OBO_REL:part_of GO:0007067 mitotic chromosome segregation mitotic sister-chromatid adhesion release GO:0000072 M phase specific microtubule process biological_process A microtubule-based process that occurs only during M phase of the cell cycle. mah GOC GO:0007017 OBO_REL:part_of GO:0000279 M-phase specific microtubule process GO:0000073 spindle pole body separation GO:0030475 biological_process A largely uncharacterized process involving the release of duplicated spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane. Duplicated SPBs are connected by a bridge structure that may be severed in order to release the SPBs from one another. Following liberation, SPBs diffuse through the nuclear membrane until they are across from each other. SPB separation must take place in order for a bipolar mitotic spindle to assemble. sgd_curators GOC GO:0022402 OBO_REL:part_of GO:0051300 spindle pole body separation (sensu Fungi) spindle pole body separation (sensu Saccharomyces) GO:0000075 cell cycle checkpoint biological_process A point in the eukaryotic cell cycle where progress through the cycle can be halted until conditions are suitable for the cell to proceed to the next stage. mah GOC 0815316194 ISBN GO:0051726 212094 Reactome 221853 Reactome 230421 Reactome 238463 Reactome 245004 Reactome 249905 Reactome 252621 Reactome 255806 Reactome 259199 Reactome 262557 Reactome 265381 Reactome 268515 Reactome 274237 Reactome 280705 Reactome 282912 Reactome 286730 Reactome 69620 Reactome GO:0000076 DNA replication checkpoint biological_process A signal transduction based surveillance mechanism that prevents the initiation of mitosis until DNA replication is complete, thereby ensuring that progeny inherit a full complement of the genome. rn GOC 11728327 PMID 12537518 PMID GO:0031570 GO:0032297 GO:0000077 DNA damage checkpoint biological_process A signal transduction pathway, induced by DNA damage, that blocks cell cycle progression (in G1, G2 or metaphase) or slows the rate at which S phase proceeds. 11891124 PMID GO:0031570 GO:0042770 DNA damage response, signal transduction resulting in cell cycle arrest GO:0000078 cell morphogenesis checkpoint biological_process A cell cycle checkpoint observed when aspects of polarity control are defective, which maintains coordination between the process of cellular morphogenesis and the nuclear events of the cell cycle. For example, in budding yeast cell-cycle delay or arrest is induced when aspects of bud formation are defective. vw GOC 14644188 PMID GO:0007093 OBO_REL:part_of GO:0000902 GO:0000079 regulation of cyclin-dependent protein kinase activity biological_process Any process that modulates the frequency, rate or extent of CDK activity. go_curators GOC GO:0045859 GO:0051726 regulation of CDK activity GO:0000080 G1 phase of mitotic cell cycle biological_process Progression through G1 phase, one of two 'gap' phases in the mitotic cell cycle; G1 is the interval between the completion of mitosis and the beginning of DNA synthesis. 0815316194 ISBN GO:0051318 OBO_REL:part_of GO:0051329 212033 Reactome 221797 Reactome 230372 Reactome 238411 Reactome 69236 Reactome GO:0000082 G1/S transition of mitotic cell cycle biological_process Progression from G1 phase to S phase of the mitotic cell cycle. mah GOC GO:0022402 OBO_REL:part_of GO:0051329 212021 Reactome 221784 Reactome 230362 Reactome 238403 Reactome 244953 Reactome 249850 Reactome 252607 Reactome 255745 Reactome 259140 Reactome 262495 Reactome 265325 Reactome 268498 Reactome 274174 Reactome 280647 Reactome 282899 Reactome 286666 Reactome 288375 Reactome 289876 Reactome 290408 Reactome 291794 Reactome 293774 Reactome 69206 Reactome GO:0000083 G1/S-specific transcription in mitotic cell cycle biological_process Any process that regulates transcription such that the target genes are transcribed during the G1/S phase of the mitotic cell cycle. mah GOC GO:0006357 GO:0022402 OBO_REL:part_of GO:0000082 69205 Reactome GO:0000084 S phase of mitotic cell cycle biological_process Progression through S phase, the part of the mitotic cell cycle during which DNA synthesis takes place. 0815316194 ISBN GO:0051320 OBO_REL:part_of GO:0051329 GO:0000085 G2 phase of mitotic cell cycle biological_process Progression through G2 phase, one of two 'gap' phases in the mitotic cell cycle; G2 is the interval between the completion of DNA synthesis and the beginning of mitosis. 0815316194 ISBN GO:0051319 OBO_REL:part_of GO:0051329 211891 Reactome 221655 Reactome 230246 Reactome 238281 Reactome 244852 Reactome 249746 Reactome 268392 Reactome 274099 Reactome 280573 Reactome 68911 Reactome GO:0000086 G2/M transition of mitotic cell cycle biological_process Progression from G2 phase to M phase of the mitotic cell cycle. mah GOC GO:0022402 OBO_REL:part_of GO:0051329 211972 Reactome 221737 Reactome 230316 Reactome 238398 Reactome 244912 Reactome 249804 Reactome 252543 Reactome 255721 Reactome 259114 Reactome 262473 Reactome 265322 Reactome 268466 Reactome 274171 Reactome 280644 Reactome 282855 Reactome 286663 Reactome 69275 Reactome GO:0000087 M phase of mitotic cell cycle biological_process Progression through M phase, the part of the mitotic cell cycle during which mitosis takes place. mah GOC 0815316194 ISBN GO:0000279 OBO_REL:part_of GO:0000278 M-phase of mitotic cell cycle 212043 Reactome 221806 Reactome 230379 Reactome 238418 Reactome 244995 Reactome 249877 Reactome 252596 Reactome 255795 Reactome 259176 Reactome 262532 Reactome 265359 Reactome 268488 Reactome 282892 Reactome 286702 Reactome 68886 Reactome GO:0000088 mitotic prophase biological_process Progression through prophase, the initial stage of mitosis in which the chromosomes are condensed but are not yet attached to a mitotic spindle. 0815316194 ISBN GO:0051324 OBO_REL:part_of GO:0007067 211977 Reactome 221742 Reactome 230322 Reactome 238359 Reactome 244917 Reactome 249807 Reactome 252546 Reactome 255723 Reactome 259116 Reactome 262475 Reactome 268434 Reactome 286639 Reactome 68875 Reactome GO:0000089 mitotic metaphase biological_process Progression through metaphase, the stage of mitosis at which chromosomes are firmly attached to the mitotic spindle at its equator but have not yet segregated to opposite poles. 0815316194 ISBN GO:0051323 OBO_REL:part_of GO:0007067 68879 Reactome GO:0000090 mitotic anaphase biological_process Progression through anaphase, the stage of mitosis during which the two sets of chromosomes separate and move away from each other. 0815316194 ISBN GO:0051322 OBO_REL:part_of GO:0007067 68882 Reactome GO:0000091 mitotic anaphase A biological_process Progression through anaphase A, the part of mitotic anaphase in which the kinetochore microtubules shorten as chromosomes move toward the spindle poles. 0815316194 ISBN GO:0000090 GO:0000092 mitotic anaphase B biological_process Progression through anaphase B, the part of mitotic anaphase in which the polar microtubules elongate and the two poles of the spindle move farther apart. 0815316194 ISBN GO:0000090 GO:0000093 mitotic telophase biological_process Progression through telophase, the last of the stages of mitosis; in the canonical cell cycle, telophase begins when the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts. 0721662544 ISBN Dorland's Illustrated Medical Dictionary GO:0051326 OBO_REL:part_of GO:0007067 GO:0000094 septin assembly and septum formation biological_process OBSOLETE (was not defined before being made obsolete). go_curators GOC This term was made obsolete because it was not defined and the string name implied two separate processes. 1 GO:0000917 GO:0000918 GO:0000921 GO:0000096 sulfur amino acid metabolic process biological_process The chemical reactions and pathways involving amino acids containing sulfur, comprising cysteine, homocysteine, methionine and selenocysteine. ai GOC gosubset_prok GO:0006520 GO:0006790 sulfur amino acid metabolism sulphur amino acid metabolic process sulphur amino acid metabolism GO:0000097 sulfur amino acid biosynthetic process biological_process The chemical reactions and pathways resulting in the formation of amino acids containing sulfur, comprising cysteine, methionine and selenocysteine. ai GOC gosubset_prok GO:0000096 GO:0008652 GO:0044272 sulfur amino acid anabolism sulfur amino acid biosynthesis sulfur amino acid formation sulfur amino acid synthesis sulphur amino acid biosynthesis sulphur amino acid biosynthetic process GO:0000098 sulfur amino acid catabolic process biological_process The chemical reactions and pathways resulting in the breakdown of amino acids containing sulfur, comprising cysteine, methionine and selenocysteine. ai GOC gosubset_prok GO:0000096 GO:0009063 GO:0044273 sulfur amino acid breakdown sulfur amino acid catabolism sulfur amino acid degradation sulphur amino acid catabolic process sulphur amino acid catabolism GO:0000101 sulfur amino acid transport biological_process The directed movement of amino acids containing sulfur (cystine, methionine and their derivatives) into, out of, within or between cells. ai GOC gosubset_prok GO:0006865 sulphur amino acid transport GO:0000103 sulfate assimilation biological_process The pathways by which inorganic sulfate is processed and incorporated into sulfated compounds. jl GOC gosubset_prok GO:0006791 sulphate assimilation GO:0000105 histidine biosynthetic process biological_process The chemical reactions and pathways resulting in the formation of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid. go_curators GOC gosubset_prok GO:0006547 GO:0009076 histidine anabolism histidine biosynthesis histidine formation histidine synthesis HISTSYN-PWY MetaCyc GO:0000114 G1-specific transcription in mitotic cell cycle biological_process Any process that regulates transcription such that the target genes are transcribed during the G1 phase of the mitotic cell cycle. mah GOC GO:0006357 GO:0022402 OBO_REL:part_of GO:0000080 GO:0000115 S-phase-specific transcription in mitotic cell cycle biological_process A cell cycle process that regulates transcription such that the target genes are transcribed during the S phase of the mitotic cell cycle. mah GOC GO:0006357 GO:0022402 OBO_REL:part_of GO:0000084 S-specific transcription in mitotic cell cycle 69241 Reactome GO:0000116 G2-specific transcription in mitotic cell cycle biological_process Any process that regulates transcription such that the target genes are transcribed during the G2 phase of the mitotic cell cycle. mah GOC GO:0006357 GO:0022402 OBO_REL:part_of GO:0000085 GO:0000117 G2/M-specific transcription in mitotic cell cycle biological_process Any process that regulates transcription such that the target genes are transcribed during the G2/M phase of the mitotic cell cycle. mah GOC GO:0006357 GO:0022402 OBO_REL:part_of GO:0000086 69274 Reactome GO:0000122 negative regulation of transcription from RNA polymerase II promoter biological_process Any process that stops, prevents or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter. go_curators GOC GO:0006357 GO:0045892 negatively_regulates GO:0006366 down regulation of transcription from RNA polymerase II promoter down-regulation of transcription from RNA polymerase II promoter downregulation of transcription from RNA polymerase II promoter inhibition of transcription from RNA polymerase II promoter negative regulation of transcription from Pol II promoter GO:0000128 flocculation biological_process The non-sexual aggregation of single-celled organisms. jl GOC goslim_pir gosubset_prok GO:0051704 GO:0000132 establishment of mitotic spindle orientation GO:0030607 GO:0030609 biological_process A cell cycle process that sets the alignment of mitotic spindle relative to other cellular structures. ems GOC GO:0040001 GO:0051294 establishment of spindle orientation during mitosis mitotic spindle orientation mitotic spindle orientation (sensu Fungi) mitotic spindle orientation (sensu Saccharomyces) orienting of mitotic spindle GO:0000135 septin checkpoint biological_process A cell cycle checkpoint that detects septin defects and responds by inhibiting the mitotic CDK. In Saccharomyces cerevisiae, correct formation of a functional septin cytoskeleton permits the cell to switch to isotropic bud growth and the onset of mitotic chromosome segregation. In the presence of septin defects, the mitotic CDK is inhibited and both the switch to isotropic bud growth and the onset of mitotic chromosome segregation is delayed. 9925642 PMID GO:0031565 GO:0000147 actin cortical patch assembly biological_process Assembly of an actin cortical patch, a discrete actin-containing structure found at the plasma membrane of fungal cells. mah GOC GO:0022607 GO:0030866 GO:0000154 rRNA modification GO:0016548 biological_process The covalent alteration of one or more nucleotides within an rRNA molecule to produce an rRNA molecule with a sequence that differs from that coded genetically. curators GOC The term 'RNA editing' (GO:0016547) was merged into 'RNA modification' (GO:0009451) on the basis of statements in the preface of Modification and Editing of RNA (ISBN:1555811337) that there is no clear distinction between modification and editing. Parallel changes were made for substrate (e.g. tRNA, rRNA, etc.) specific child terms of 'RNA editing'. gosubset_prok GO:0006364 GO:0009451 rRNA editing GO:0000160 two-component signal transduction system (phosphorelay) biological_process A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins. 9191038 PMID gosubset_prok GO:0007165 histidyl-aspartyl phosphorelay GO:0000161 MAPKKK cascade during osmolarity sensing biological_process MAPKKK cascade involved in signal transduction in response to change in osmotic conditions. 9561267 PMID GO:0000165 OBO_REL:part_of GO:0007231 osmolarity sensing, MAPKKK cascade GO:0000162 tryptophan biosynthetic process GO:0009096 biological_process The chemical reactions and pathways resulting in the formation of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid; tryptophan is synthesized from chorismate via anthranilate. mah GOC 0471331309 ISBN Biochemical Pathways TRPSYN-PWY MetaCyc gosubset_prok GO:0006568 GO:0009073 GO:0046219 aromatic amino acid family biosynthetic process, anthranilate pathway tryptophan anabolism tryptophan biosynthesis tryptophan formation tryptophan synthesis TRPSYN-PWY MetaCyc GO:0000165 MAPKKK cascade biological_process Cascade of at least three protein kinase activities culminating in the phosphorylation and activation of a MAP kinase. MAPKKK cascades lie downstream of numerous signaling pathways. mah GOC 9561267 PMID GO:0007243 ERK/MAPK cascade MAP kinase cascade MAP kinase kinase kinase cascade MAPK cascade MAPK signaling MAPK signalling MAPKKK cascade during sporulation (sensu Fungi) MAPKKK cascade during sporulation (sensu Saccharomyces) 109869 Reactome 211967 Reactome 221732 Reactome 230313 Reactome 238351 Reactome 244909 Reactome 249802 Reactome 252619 Reactome 255804 Reactome 259197 Reactome 262555 Reactome 268509 Reactome 274234 Reactome 280703 Reactome 286727 Reactome GO:0000167 activation of MAPKKK activity during osmolarity sensing biological_process Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase during osmolarity sensing. 9561267 PMID GO:0000185 OBO_REL:part_of GO:0000161 activation of MAP kinase kinase kinase activity during osmolarity sensing osmolarity sensing, activation of MAP kinase kinase kinase activity osmolarity sensing, activation of MAPKKK activity GO:0000168 activation of MAPKK activity during osmolarity sensing GO:0007233 biological_process Any process that initiates the activity of the inactive enzyme MAP kinase kinase during osmolarity sensing. 9561267 PMID GO:0000186 OBO_REL:part_of GO:0000161 activation of MAP kinase kinase activity during osmolarity sensing activation of Pbs2 kinase osmolarity sensing, activation of MAP kinase kinase activity osmolarity sensing, activation of MAPKK activity GO:0000169 activation of MAPK activity during osmolarity sensing biological_process Any process that initiates the activity of the inactive enzyme MAP kinase activity during osmolarity sensing. 9561267 PMID GO:0000187 OBO_REL:part_of GO:0000161 osmolarity sensing, activation of MAPK activity GO:0000173 inactivation of MAPK activity during osmolarity sensing biological_process Any process that terminates the activity of the active enzyme MAP kinase during osmolarity sensing. 9561267 PMID GO:0000188 OBO_REL:part_of GO:0000161 osmolarity sensing, inactivation of MAPK osmolarity sensing, termination of MAPK activity termination of MAPK activity during osmolarity sensing GO:0000174 inactivation of MAPK (mating sensu Saccharomyces) biological_process OBSOLETE. Downregulation of MAP kinase activity in the context of transduction of mating pheromone signal, as described for Saccharomyces. 9561267 PMID This term was made obsolete because it is a gene product specific term. 1 GO:0000750 GO:0000183 chromatin silencing at rDNA biological_process Repression of transcription of ribosomal DNA by the formation of heterochromatin. 10219245 PMID GO:0006342 chromatin silencing at ribosomal DNA heterochromatic silencing at rDNA GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay biological_process The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins. krc GOC ma GOC 10025395 PMID GO:0000956 mRNA breakdown, nonsense-mediated decay mRNA catabolic process, nonsense-mediated mRNA catabolism, nonsense-mediated mRNA degradation, nonsense-mediated decay nonsense-mediated mRNA decay nuclear mRNA catabolic process, nonsense-mediated decay GO:0000185 activation of MAPKKK activity biological_process Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase. 9561267 PMID GO:0032147 OBO_REL:part_of GO:0000165 activation of MAP kinase kinase kinase activation of MAPKKK during sporulation (sensu Fungi) activation of MAPKKK during sporulation (sensu Saccharomyces) positive regulation of MAP kinase kinase kinase activity positive regulation of MAPKKK activity GO:0000186 activation of MAPKK activity GO:0007255 biological_process The initiation of the activity of the inactive enzyme MAP kinase kinase by phosphorylation by a MAPKKK. 9561267 PMID GO:0006468 GO:0032147 OBO_REL:part_of GO:0000165 activation of MAP kinase kinase activity activation of MAP/ERK kinase kinase activation of MAPKK during sporulation (sensu Fungi) activation of MAPKK during sporulation (sensu Saccharomyces) positive regulation of MAPKK activity 110049 Reactome 211601 Reactome 221376 Reactome 230014 Reactome 238032 Reactome 244648 Reactome 249583 Reactome GO:0000187 activation of MAPK activity biological_process The initiation of the activity of the inactive enzyme MAP kinase by phosphorylation by a MAPKK. 9561267 PMID GO:0006468 GO:0043406 OBO_REL:part_of GO:0000165 activation of MAP kinase activation of MAPK during sporulation (sensu Fungi) activation of MAPK during sporulation (sensu Saccharomyces) MAPK activation 112409 Reactome 212039 Reactome 221803 Reactome 230377 Reactome 238416 Reactome 244963 Reactome 249842 Reactome 252574 Reactome 255755 Reactome 259149 Reactome 262506 Reactome 268461 Reactome 274183 Reactome 280656 Reactome 286675 Reactome GO:0000188 inactivation of MAPK activity biological_process Any process that terminates the activity of the active enzyme MAP kinase. 9561267 PMID GO:0043407 OBO_REL:part_of GO:0000165 inactivation of MAPK during sporulation (sensu Fungi) inactivation of MAPK during sporulation (sensu Saccharomyces) termination of MAPK activity GO:0000189 nuclear translocation of MAPK biological_process The directed movement of a MAP kinase to the nucleus upon activation. 9561267 PMID GO:0000060 OBO_REL:part_of GO:0000165 109867 Reactome 109868 Reactome 112353 Reactome 209891 Reactome 209896 Reactome 228348 Reactome 228351 Reactome 236568 Reactome 236573 Reactome 243599 Reactome 243605 Reactome 248698 Reactome 248703 Reactome 251790 Reactome 251793 Reactome 254938 Reactome 254943 Reactome 258208 Reactome 258211 Reactome 261726 Reactome 261729 Reactome 267714 Reactome 267717 Reactome 273179 Reactome 273186 Reactome 279660 Reactome 279666 Reactome 285768 Reactome 285771 Reactome GO:0000190 MAPKKK cascade (pseudohyphal growth) biological_process OBSOLETE. MAPKKK cascade involved in transduction of signal promoting pseudohyphal or invasive growth. 9561267 PMID This term was made obsolete because it is a gene product specific term. 1 GO:0000191 activation of MAPKKK (pseudohyphal growth) biological_process OBSOLETE. Upregulation of MAPKKK activity in the context of regulating pseudohyphal or invasive growth. 9561267 PMID This term was made obsolete because it is a gene product specific term. 1 GO:0000192 activation of MAPKK (pseudohyphal growth) biological_process OBSOLETE. Upregulation of a MAP kinase kinase in the context of regulating pseudohyphal or invasive growth. 9561267 PMID This term was made obsolete because it is a gene product specific term. 1 GO:0000193 activation of MAPK (pseudohyphal growth) biological_process OBSOLETE. Upregulation of MAP kinase activity in the context of regulating pseudohyphal or invasive growth. 9561267 PMID This term was made obsolete because it is a gene product specific term. 1 GO:0000194 inactivation of MAPK (pseudohyphal growth) biological_process OBSOLETE. Downregulation of MAP kinase activity in the context of regulating pseudohyphal or invasive growth. 9561267 PMID This term was made obsolete because it is a gene product specific term. 1 GO:0000195 nuclear translocation of MAPK (pseudohyphal growth) biological_process OBSOLETE. Movement of a MAP kinase to the nucleus in the context of regulating pseudohyphal or invasive growth. 9561267 PMID This term was made obsolete because it is a gene product specific term. 1 GO:0000196 MAPKKK cascade during cell wall biogenesis biological_process Cascade of at least three protein kinase activities culminating in the phosphorylation and activation of a MAP kinase that occurs during cell wall biogenesis, the assembly and arrangement of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells. 9561267 PMID GO:0000165 OBO_REL:part_of GO:0007047 cell wall biogenesis, MAPKKK cascade GO:0000197 activation of MAPKKK activity during cell wall biogenesis biological_process Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase during cell wall biogenesis, the assembly and arrangement of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells. 9561267 PMID GO:0000185 OBO_REL:part_of GO:0000196 activation of MAP kinase kinase kinase activity during cell wall biogenesis cell wall biogenesis, activation of MAP kinase kinase kinase activity cell wall biogenesis, activation of MAPKKK activity GO:0000198 activation of MAPKK activity during cell wall biogenesis biological_process Any process that initiates the activity of the inactive enzyme MAP kinase kinase during cell wall biogenesis, the assembly and arrangement of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells. 9561267 PMID GO:0000186 OBO_REL:part_of GO:0000196 activation of MAP kinase kinase activity during cell wall biogenesis cell wall biogenesis, activation of MAP kinase kinase activity cell wall biogenesis, activation of MAPKK activity GO:0000199 activation of MAPK activity during cell wall biogenesis biological_process Any process that initiates the activity of the inactive enzyme MAP kinase during cell wall biogenesis, the assembly and arrangement of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells. 9561267 PMID GO:0000187 OBO_REL:part_of GO:0000196 cell wall biogenesis, activation of MAPK activity GO:0000200 inactivation of MAPK activity during cell wall biogenesis biological_process Any process that terminates the activity of the active enzyme MAP kinase during cell wall biogenesis, the assembly and arrangement of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells. 9561267 PMID GO:0000188 OBO_REL:part_of GO:0000196 cell wall biogenesis, inactivation of MAPK activity cell wall biogenesis, termination of MAPK activity termination of MAPK activity during cell wall biogenesis GO:0000201 nuclear translocation of MAPK during cell wall biogenesis biological_process The directed movement of a MAP kinase to the nucleus during cell wall biogenesis, the assembly and arrangement of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells. 9561267 PMID GO:0000189 OBO_REL:part_of GO:0000196 cell wall biogenesis, nuclear translocation of MAPK GO:0000202 MAPKKK cascade during sporulation (sensu Saccharomyces) biological_process OBSOLETE. MAPKKK cascade involved in transduction of signal promoting sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930). 9561267 PMID This term was made obsolete because it is a gene product specific term. 1 GO:0000203 activation of MAPKKK during sporulation (sensu Saccharomyces) biological_process OBSOLETE. Upregulation of MAPKKK activity in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930). 9561267 PMID This term was made obsolete because it is a gene product specific term. 1 GO:0000204 activation of MAPKK during sporulation (sensu Saccharomyces) biological_process OBSOLETE. Upregulation of a MAP kinase kinase in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930). 9561267 PMID This term was made obsolete because it is a gene product specific term. 1 GO:0000205 activation of MAPK during sporulation (sensu Saccharomyces) biological_process OBSOLETE. Upregulation of MAP kinase activity in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930). 9561267 PMID This term was made obsolete because it is a gene product specific term. 1 GO:0000206 inactivation of MAPK during sporulation (sensu Saccharomyces) biological_process OBSOLETE. Downregulation of MAP kinase activity in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930). 9561267 PMID This term was made obsolete because it is a gene product specific term. 1 GO:0000207 nuclear translocation of MAPK during sporulation (sensu Saccharomyces) biological_process OBSOLETE. Movement of a MAP kinase to the nucleus in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930). 9561267 PMID This term was made obsolete because it is a gene product specific term. 1 GO:0000208 nuclear translocation of MAPK during osmolarity sensing biological_process The directed movement of a MAP kinase to the nucleus during osmolarity sensing. 9561267 PMID GO:0000189 OBO_REL:part_of GO:0000161 osmolarity sensing, nuclear translocation of MAPK GO:0000209 protein polyubiquitination biological_process Addition of multiple ubiquitin moieties to a protein, forming a ubiquitin chain. 0815316194 ISBN GO:0016567 polyubiquitin protein polyubiquitinylation protein polyubiquitylation GO:0000212 meiotic spindle organization and biogenesis biological_process A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of the microtubule spindle during a meiotic cell cycle. mah GOC GO:0007051 GO:0022402 OBO_REL:part_of GO:0051321 meiotic spindle organisation and biogenesis spindle organization and biogenesis during meiosis GO:0000216 M/G1 transition of mitotic cell cycle biological_process Progression from M phase to G1 phase of the mitotic cell cycle. mah GOC GO:0022402 OBO_REL:part_of GO:0051329 211997 Reactome 221761 Reactome 230342 Reactome 238378 Reactome 244933 Reactome 249898 Reactome 252623 Reactome 255800 Reactome 259165 Reactome 262551 Reactome 265375 Reactome 274161 Reactome 280634 Reactome 286652 Reactome 68874 Reactome GO:0000226 microtubule cytoskeleton organization and biogenesis biological_process A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins. mah GOC GO:0007017 GO:0000236 mitotic prometaphase biological_process Progression through prometaphase, the stage following prophase in mitosis (in higher eukaryotes) during which the nuclear envelope is disrupted and breaks into membrane vesicles, and the spindle microtubules enter the nuclear region. Kinetochores mature on each centromere and attach to some of the spindle microtubules. Kinetochore microtubules begin the process of aligning chromosomes in one plane halfway between the poles. mah GOC 0198547684 ISBN GO:0022403 OBO_REL:part_of GO:0007067 68877 Reactome GO:0000237 leptotene biological_process Progression through the first stage of prophase I in meiosis, in which chromosomes first become visible. 0198547684 ISBN GO:0022403 OBO_REL:part_of GO:0007128 GO:0000238 zygotene biological_process Progression through the second stage of prophase I in meiosis, in which each chromosome pairs with its homolog; the two become aligned and crossing over may occur. 0198547684 ISBN GO:0022403 OBO_REL:part_of GO:0007128 GO:0000239 pachytene biological_process Progression through the third stage of prophase I in meiosis, in which crossing over occurs between a chromatid in one partner and another chromatid in the homologous chromosome. 0198547684 ISBN GO:0022403 OBO_REL:part_of GO:0007128 GO:0000240 diplotene biological_process Progression through the fourth stage of prophase I in meiosis, in which the homologous chromosomes begin to separate and the synaptonemal complex dissolves. 0198547684 ISBN GO:0022403 OBO_REL:part_of GO:0007128 GO:0000241 diakinesis biological_process Progression through the final stage of prophase I in meiosis; the transition to meiotic metaphase I. 0198547684 ISBN GO:0022403 OBO_REL:part_of GO:0007128 GO:0000244 assembly of spliceosomal tri-snRNP GO:0000351 GO:0000355 biological_process The formation of a tri-snRNP complex containing U4 and U6 (or U4atac and U6atac) snRNAs and U5 snRNAs and associated proteins. This includes reannealing of U4 and U6 (or U4atac and U6atac) snRNAs released from previous rounds of splicing to reform the U4/U6 snRNP (or U4atac/U6atac snRNP) as well as the subsequent association of the U5 snRNP with the U4/U6 snRNP (or U4atac/U6atac snRNP) to form a tri-snRNP that is ready to reassemble into another spliceosome complex. 0879695897 ISBN 9452384 PMID GO:0022618 OBO_REL:part_of GO:0000387 assembly of spliceosomal tri-snRNP U4/U6.U5 assembly of spliceosomal tri-snRNP U4atac/U6atac.U5 snRNP recycling spliceosomal tri-snRNP assembly spliceosomal tri-snRNP U4/U6.U5 assembly spliceosomal tri-snRNP U4atac/U6atac.U5 assembly GO:0000245 spliceosome assembly biological_process The aggregation, arrangement and bonding together of the spliceosome, a ribonucleoprotein apparatus that catalyzes nuclear mRNA splicing via transesterification reactions. 9476892 PMID GO:0022618 OBO_REL:part_of GO:0000398 GO:0000255 allantoin metabolic process biological_process The chemical reactions and pathways involving allantoin, (2,5-dioxo-4-imidazolidinyl)urea, an intermediate or end product of purine catabolism. mah GOC 0198547684 ISBN gosubset_prok GO:0009308 GO:0046483 allantoin metabolism GO:0000256 allantoin catabolic process biological_process The chemical reactions and pathways resulting in the breakdown of allantoin, (2,5-dioxo-4-imidazolidinyl)urea. mah GOC 0198547684 ISBN gosubset_prok GO:0000255 GO:0046700 allantoin breakdown allantoin catabolism allantoin degradation GO:0000266 mitochondrial fission biological_process The division of a mitochondrion within a cell to form two or more separate mitochondrial compartments. 11038192 PMID GO:0007005 GO:0048285 mitochondrial division mitochondrial proliferation GO:0000270 peptidoglycan metabolic process GO:0009284 biological_process The chemical reactions and pathways involving peptidoglycans, any of a class of glycoconjugates found only in bacterial cell walls and consisting of strands of glycosaminoglycan cross-linked by oligopeptides to form a huge and rigid network. http://www.dsmz.de/species/murein.htm URL 0198506732 ISBN Oxford Dictionary of Biochemistry and Molecular Biology gosubset_prok GO:0005975 murein metabolic process murein metabolism peptidoglycan metabolism GO:0000271 polysaccharide biosynthetic process biological_process The chemical reactions and pathways resulting in the formation of polysaccharides, polymers of more than 10 monosaccharide residues joined by glycosidic linkages. go_curators GOC gosubset_prok GO:0016051 GO:0043284 glycan biosynthesis glycan biosynthetic process polysaccharide anabolism polysaccharide biosynthesis polysaccharide formation polysaccharide synthesis GO:0000272 polysaccharide catabolic process biological_process The chemical reactions and pathways resulting in the breakdown of polysaccharides, polymers of more than 10 monosaccharide residues joined by glycosidic linkages. go_curators GOC gosubset_prok GO:0005976 GO:0043285 polysaccharide breakdown polysaccharide catabolism polysaccharide degradation GO:0000273 lipoic acid metabolic process biological_process The chemical reactions and pathways involving lipoic acid, 1,2-dithiolane-3-pentanoic acid, a coenzyme involved in oxidative decarboxylation of keto acids. ai GOC http://cancerweb.ncl.ac.uk/ URL gosubset_prok GO:0006732 GO:0019752 GO:0046483 lipoic acid metabolism GO:0000278 mitotic cell cycle biological_process Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent. mah GOC 0815316194 ISBN 69278 Reactome GO:0007049 212083 Reactome 221841 Reactome 230408 Reactome 238450 Reactome 244991 Reactome 249871 Reactome 252608 Reactome 255794 Reactome 259188 Reactome 262544 Reactome 265374 Reactome 268486 Reactome 274210 Reactome 280680 Reactome 282900 Reactome 286715 Reactome 288392 Reactome 289890 Reactome 290421 Reactome 291802 Reactome 293782 Reactome 69278 Reactome GO:0000279 M phase biological_process Progression through M phase, the part of the cell cycle comprising nuclear division. 0815316194 ISBN GO:0022403 M-phase GO:0000280 nuclear division biological_process The partitioning of the nucleus and its genetic information. bf GOC jl GOC http://www.biology-online.org/ URL goslim_pir GO:0009987 karyokinesis GO:0000281 cytokinesis after mitosis biological_process A cell cycle process that results in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells. ai GOC GO:0033205 GO:0000282 cellular bud site selection biological_process The specification of the site where a daughter cell will form, in organisms that reproduce by budding. mah GOC Note that this term was split from 'bud site selection/establishment of cell polarity (sensu Saccharomyces) ; GO:0007115' (sibling term 'establishment of cell polarity (sensu Saccharomyces) ; GO:0000283'). GO:0007105 GO:0030010 bud site selection/establishment of cell polarity (sensu Saccharomyces) GO:0000284 shmoo orientation biological_process OBSOLETE (was not defined before being made obsolete). elh GOC This term was made obsolete because it is an organism specific term. The entire branch of the ontology was reorganized to be more generally applicable. 1 GO:0000753 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay biological_process A major pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of ordered steps: poly(A) tail shortening, deadenylylation-dependent decapping, and decay of the transcript body, and that can regulate mRNA stability. krc GOC GO:0000956 deadenylation-dependent mRNA decay mRNA breakdown, deadenylation-dependent decay mRNA catabolic process, deadenylation-dependent mRNA catabolic process, deadenylylation-dependent mRNA catabolism, deadenylation-dependent mRNA catabolism, deadenylylation-dependent mRNA degradation, deadenylation-dependent decay nuclear mRNA catabolic process, deadenylation-dependent decay GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening biological_process Shortening of the poly(A) tail of a nuclear-transcribed mRNA from full length to an oligo(A) length. krc GOC GO:0000956 OBO_REL:part_of GO:0000288 3' to 5' mRNA deadenylation mRNA deadenylation nuclear mRNA poly(A) tail shortening GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA biological_process Cleavage of the 5'-cap of a nuclear mRNA triggered by shortening of the poly(A) tail to below a minimum functional length. krc GOC GO:0000956 OBO_REL:part_of GO:0000288 deadenylation-dependent decapping of nuclear mRNA deadenylylation-dependent decapping GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic biological_process The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs when the ends are not protected by the 5'-cap or the 3'-poly(A) tail. krc GOC GO:0000956 OBO_REL:part_of GO:0000288 OBO_REL:part_of GO:0000294 exonucleolytic degradation of mRNA mRNA breakdown, exonucleolytic mRNA degradation, exonucleolytic nuclear mRNA catabolic process, exonucleolytic GO:0000292 RNA fragment catabolic process biological_process The chemical reactions and pathways resulting in the breakdown of a fragment of RNA, such as excised introns or sequences removed from ribosomal RNA during processing. mah GOC gosubset_prok GO:0006401 RNA fragment breakdown RNA fragment catabolism RNA fragment degradation GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay biological_process A minor degradation pathway nuclear-transcribed mRNAs that begins with an endonucleolytic cleavage to generate unprotected ends. krc GOC GO:0000956 endonucleolytic mRNA decay mRNA breakdown, endonucleolytic cleavage-dependent decay mRNA catabolic process, endonucleolytic mRNA catabolism, endonucleolytic mRNA degradation, endonucleolytic cleavage-dependent decay nuclear mRNA catabolic process, endonucleolytic cleavage-dependent decay GO:0000296 spermine transport biological_process The directed movement of spermine, N,N-bis(3-aminopropyl)-1,4-diaminobutane, a polyamine formed by the transfer of a propylamine group from decarboxylated S-adenosylmethionine to spermidine, into, out of, within or between cells. krc GOC 0198506732 ISBN