format-version: 1.2
date: 24:06:2008 13:22
autogenerated-by: /usr/bin/go2fmt.pl
format-version: 1.2
date: 23:06:2008 11:12
saved-by: tanyaberardini
auto-generated-by: OBO-Edit 1.101
default-namespace: gene_ontology
remark: cvs version: $Revision: 1.224 $
synonymtypedef: systematic_synonym "Systematic synonym" EXACT
subsetdef: goslim_candida "Candida GO slim"
subsetdef: goslim_generic "Generic GO slim"
subsetdef: goslim_goa "GOA and proteome slim"
subsetdef: goslim_pir "PIR GO slim"
subsetdef: goslim_plant "Plant GO slim"
subsetdef: goslim_yeast "Yeast GO slim"
subsetdef: gosubset_prok "Prokaryotic GO subset"

[Term]
id: GO:0000001
name: mitochondrion inheritance
namespace: biological_process
def: "The distribution of mitochondria, including the mitochondrial genome, into daughter cells after mitosis or meiosis, mediated by interactions between mitochondria and the cytoskeleton." [GOC:mcc, PMID:10873824, PMID:11389764]
is_a: GO:0048308
is_a: GO:0048311
synonym: "mitochondrial inheritance" EXACT []

[Term]
id: GO:0000002
name: mitochondrial genome maintenance
namespace: biological_process
def: "The maintenance of the structure and integrity of the mitochondrial genome; includes replication and segregation of the mitochondrial chromosome." [GOC:ai, GOC:vw]
is_a: GO:0007005

[Term]
id: GO:0000003
name: reproduction
alt_id: GO:0019952
alt_id: GO:0050876
namespace: biological_process
def: "The production by an organism of new individuals that contain some portion of their genetic material inherited from that organism." [GOC:go_curators, GOC:isa_complete, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"]
subset: goslim_generic
subset: goslim_pir
subset: goslim_plant
subset: gosubset_prok
is_a: GO:0008150
synonym: "reproductive physiological process" EXACT []

[Term]
id: GO:0000011
name: vacuole inheritance
namespace: biological_process
def: "The distribution of vacuoles into daughter cells after mitosis or meiosis, mediated by interactions between vacuoles and the cytoskeleton." [GOC:mcc, PMID:10873824, PMID:14616069]
is_a: GO:0007033
is_a: GO:0048308

[Term]
id: GO:0000012
name: single strand break repair
namespace: biological_process
def: "The repair of single strand breaks in DNA. Repair of such breaks is mediated by the same enzyme systems as are used in base excision repair." [URL:http://www.ultranet.com/~jkimball/BiologyPages/D/DNArepair.html]
subset: gosubset_prok
is_a: GO:0006281

[Term]
id: GO:0000017
name: alpha-glucoside transport
namespace: biological_process
def: "The directed movement of alpha-glucosides into, out of, within or between cells. Alpha-glucosides are glycosides in which the sugar moiety is a glucose residue, and the anomeric carbon of the bond is in an alpha configuration." [GOC:jl, URL:http://www.biochem.purdue.edu/, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"]
is_a: GO:0042946

[Term]
id: GO:0000018
name: regulation of DNA recombination
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of DNA recombination, a process by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents." [GOC:go_curators, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"]
subset: gosubset_prok
is_a: GO:0051052
relationship: regulates GO:0006310

[Term]
id: GO:0000019
name: regulation of mitotic recombination
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of DNA recombination during mitosis." [GOC:go_curators]
is_a: GO:0000018
relationship: regulates GO:0006312
synonym: "regulation of recombination within rDNA repeats" NARROW []

[Term]
id: GO:0000020
name: negative regulation of recombination within rDNA repeats
namespace: biological_process
def: "OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of genetic recombination within the DNA of the genes coding for ribosomal RNA." [GOC:go_curators, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"]
comment: This term was made obsolete because it describes a substrate-specific process.
is_obsolete: true
consider: GO:0045950

[Term]
id: GO:0000022
name: mitotic spindle elongation
namespace: biological_process
def: "Lengthening of the distance between poles of the mitotic spindle." [GOC:mah]
is_a: GO:0051231
relationship: OBO_REL:part_of GO:0007052
synonym: "spindle elongation during mitosis" EXACT []

[Term]
id: GO:0000023
name: maltose metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose), an intermediate in the catabolism of glycogen and starch." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"]
subset: gosubset_prok
is_a: GO:0005984
synonym: "malt sugar metabolic process" EXACT []
synonym: "malt sugar metabolism" EXACT []
synonym: "maltose metabolism" EXACT []

[Term]
id: GO:0000024
name: maltose biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose)." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"]
subset: gosubset_prok
is_a: GO:0000023
is_a: GO:0046351
synonym: "malt sugar biosynthesis" EXACT []
synonym: "malt sugar biosynthetic process" EXACT []
synonym: "maltose anabolism" EXACT []
synonym: "maltose biosynthesis" EXACT []
synonym: "maltose formation" EXACT []
synonym: "maltose synthesis" EXACT []

[Term]
id: GO:0000025
name: maltose catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose)." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"]
subset: gosubset_prok
is_a: GO:0000023
is_a: GO:0046352
synonym: "malt sugar catabolic process" EXACT []
synonym: "malt sugar catabolism" EXACT []
synonym: "maltose breakdown" EXACT []
synonym: "maltose degradation" EXACT []
synonym: "maltose hydrolysis" NARROW []
xref: MetaCyc:MALTOSECAT-PWY

[Term]
id: GO:0000027
name: ribosomal large subunit assembly and maintenance
namespace: biological_process
def: "The aggregation, arrangement and bonding together of constituent RNAs and proteins to form and maintain the large ribosomal subunit." [GOC:jl]
subset: gosubset_prok
is_a: GO:0042257
relationship: OBO_REL:part_of GO:0042273

[Term]
id: GO:0000028
name: ribosomal small subunit assembly and maintenance
namespace: biological_process
def: "The aggregation, arrangement and bonding together of constituent RNAs and proteins to form and maintain the small ribosomal subunit." [GOC:jl]
subset: gosubset_prok
is_a: GO:0042257
relationship: OBO_REL:part_of GO:0042274

[Term]
id: GO:0000032
name: cell wall mannoprotein biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of cell wall mannoproteins, any cell wall protein that contains covalently bound mannose residues other than as a moiety of nucleic acid." [GOC:ai]
subset: gosubset_prok
is_a: GO:0006057
is_a: GO:0031506
synonym: "cell wall mannoprotein anabolism" EXACT []
synonym: "cell wall mannoprotein biosynthesis" EXACT []
synonym: "cell wall mannoprotein formation" EXACT []
synonym: "cell wall mannoprotein synthesis" EXACT []

[Term]
id: GO:0000038
name: very-long-chain fatty acid metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving fatty acids with a chain length of C18 or greater." [GOC:hjd]
subset: gosubset_prok
is_a: GO:0006631
synonym: "very-long-chain fatty acid metabolism" EXACT []

[Term]
id: GO:0000040
name: low-affinity iron ion transport
namespace: biological_process
def: "The directed, low-affinity movement of iron (Fe) ions into, out of, within or between cells. In low affinity transport the transporter is able to bind the solute only if it is only present at very low concentrations." [GOC:mah]
is_a: GO:0006826
is_a: GO:0034220
synonym: "low affinity iron ion transport" EXACT []

[Term]
id: GO:0000041
name: transition metal ion transport
namespace: biological_process
def: "The directed movement of transition metal ions into, out of, within or between cells. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"]
subset: gosubset_prok
is_a: GO:0030001
synonym: "transition metal transport" EXACT []

[Term]
id: GO:0000042
name: protein targeting to Golgi
namespace: biological_process
def: "The process of directing proteins towards the Golgi using signals contained within the protein." [GOC:ai]
is_a: GO:0000301
is_a: GO:0006605
synonym: "protein-Golgi targeting" EXACT []

[Term]
id: GO:0000044
name: ascorbate stabilization
namespace: biological_process
def: "OBSOLETE. The reduction of the ascorbate free radical to a stable form." [GOC:ai, GOC:mtg_electron_transport]
comment: This term was made obsolete because it is defined as a function term and is in the process ontology.
synonym: "vitamin C stabilization" EXACT []
is_obsolete: true

[Term]
id: GO:0000045
name: autophagic vacuole formation
namespace: biological_process
def: "The formation of a double membrane-bounded structure, the autophagosome, that occurs when a specialized membrane sac, called the isolation membrane, starts to enclose a portion of the cytoplasm." [PMID:9412464]
is_a: GO:0016050
relationship: OBO_REL:part_of GO:0016236
synonym: "autophagosome biosynthesis" EXACT []
synonym: "autophagosome formation" EXACT []
synonym: "PAS formation" NARROW []

[Term]
id: GO:0000046
name: autophagic vacuole fusion
namespace: biological_process
def: "The fusion of an autophagic vacuole with a vacuole (yeast) or lysosome (e.g. mammals and insects). In the case of yeast, inner membrane-bounded structures (autophagic bodies) appear in the vacuole." [PMID:11099404]
is_a: GO:0006944
is_a: GO:0048284
relationship: OBO_REL:part_of GO:0016236
synonym: "fusion of autophagosome with lysosome" NARROW []

[Term]
id: GO:0000050
name: urea cycle
alt_id: GO:0006594
alt_id: GO:0006871
namespace: biological_process
def: "A cyclic metabolic pathway that converts waste nitrogen in the form of ammonium to urea." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"]
is_a: GO:0019627
synonym: "ornithine cycle" EXACT []
synonym: "urea biosynthesis" EXACT []
synonym: "urea biosynthetic process" EXACT []
xref: Reactome:211547
xref: Reactome:221324
xref: Reactome:229964
xref: Reactome:237981
xref: Reactome:244600
xref: Reactome:249543
xref: Reactome:252354
xref: Reactome:255509
xref: Reactome:258881
xref: Reactome:262258
xref: Reactome:265108
xref: Reactome:268232
xref: Reactome:273914
xref: Reactome:280393
xref: Reactome:282778
xref: Reactome:286409
xref: Reactome:288203
xref: Reactome:289764
xref: Reactome:290323
xref: Reactome:291648
xref: Reactome:292335
xref: Reactome:293622
xref: Reactome:70635

[Term]
id: GO:0000051
name: urea cycle intermediate metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving any of the intermediate compounds involved in the urea cycle, a cyclic metabolic pathway that converts waste nitrogen in the form of ammonium to urea." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"]
subset: gosubset_prok
is_a: GO:0008152
relationship: OBO_REL:part_of GO:0006807
synonym: "urea cycle intermediate metabolism" EXACT []

[Term]
id: GO:0000052
name: citrulline metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"]
subset: gosubset_prok
is_a: GO:0000051
is_a: GO:0019794
synonym: "citrulline metabolism" EXACT []

[Term]
id: GO:0000053
name: argininosuccinate metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving argininosuccinate, 2-(Nw-arginino)succinate, an intermediate in the ornithine-urea cycle, where it is synthesized from citrulline and aspartate." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"]
is_a: GO:0000051
synonym: "argininosuccinate metabolism" EXACT []

[Term]
id: GO:0000054
name: ribosome export from nucleus
namespace: biological_process
def: "The directed movement of a ribosome from the nucleus into the cytoplasm." [GOC:ai]
is_a: GO:0033753
is_a: GO:0051168
relationship: OBO_REL:part_of GO:0042254
synonym: "ribosome export out of nucleus" EXACT []
synonym: "ribosome transport from nucleus to cytoplasm" EXACT []
synonym: "ribosome-nucleus export" EXACT []

[Term]
id: GO:0000055
name: ribosomal large subunit export from nucleus
alt_id: GO:0000057
namespace: biological_process
def: "The directed movement of a ribosomal large subunit from the nucleus into the cytoplasm." [GOC:mah]
is_a: GO:0000054
synonym: "ribosomal large subunit export out of nucleus" EXACT []
synonym: "ribosomal large subunit transport from nucleus to cytoplasm" EXACT []
synonym: "ribosomal large subunit-nucleus export" EXACT []

[Term]
id: GO:0000056
name: ribosomal small subunit export from nucleus
alt_id: GO:0000058
namespace: biological_process
def: "The directed movement of a ribosomal small subunit from the nucleus into the cytoplasm." [GOC:mah]
is_a: GO:0000054
synonym: "ribosomal small subunit export out of nucleus" EXACT []
synonym: "ribosomal small subunit transport from nucleus to cytoplasm" EXACT []
synonym: "ribosomal small subunit-nucleus export" EXACT []

[Term]
id: GO:0000059
name: protein import into nucleus, docking
namespace: biological_process
def: "The aggregation, arrangement and bonding together of the nuclear localization signal of a protein with nuclear envelope proteins such as importins." [GOC:isa_complete, PMID:7878057]
is_a: GO:0043623
relationship: OBO_REL:part_of GO:0006606
synonym: "protein docking during protein import into nucleus" EXACT []
synonym: "protein docking during protein transport from cytoplasm to nucleus" EXACT []
synonym: "protein docking during protein-nucleus import" EXACT []
synonym: "protein transport from cytoplasm to nucleus, docking" EXACT []
synonym: "protein-nucleus import, docking" EXACT []

[Term]
id: GO:0000060
name: protein import into nucleus, translocation
namespace: biological_process
def: "The vectorial transfer of a protein from the cytoplasm into the nucleus, through the nuclear pore and across the nuclear envelope." [GOC:jl, GOC:vw, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"]
is_a: GO:0006886
relationship: OBO_REL:part_of GO:0006606
synonym: "protein translocation during protein import into nucleus" EXACT []
synonym: "protein translocation during protein transport from cytoplasm to nucleus" EXACT []
synonym: "protein translocation during protein-nucleus import" EXACT []
synonym: "protein transport from cytoplasm to nucleus, translocation" EXACT []
synonym: "protein-nucleus import, translocation" EXACT []

[Term]
id: GO:0000061
name: protein import into nucleus, substrate release
namespace: biological_process
def: "The disaggregation of a protein complex composed of the nuclear localization sequence and the importin alpha, and importin beta proteins." [PMID:9687515]
is_a: GO:0043624
relationship: OBO_REL:part_of GO:0006606
synonym: "protein substrate release during protein import into nucleus" EXACT []
synonym: "protein substrate release during protein transport from cytoplasm to nucleus" EXACT []
synonym: "protein substrate release during protein-nucleus import" EXACT []
synonym: "protein transport from cytoplasm to nucleus, substrate release" EXACT []
synonym: "protein-nucleus import, substrate release" EXACT []

[Term]
id: GO:0000066
name: mitochondrial ornithine transport
namespace: biological_process
def: "The directed movement of ornithine, 2,5-diaminopentanoic acid, into, out of or within a mitochondrion." [GOC:ai]
is_a: GO:0006839
is_a: GO:0015822

[Term]
id: GO:0000067
name: DNA replication and chromosome cycle
namespace: biological_process
def: "OBSOLETE (was not defined before being made obsolete)." [GOC:ai]
comment: This term was made obsolete because it has been superseded by more accurate terms to represent the biological processes occurring, and it is not clear that this term represents a useful concept.
is_obsolete: true
consider: GO:0006260
consider: GO:0007059
consider: GO:0051276

[Term]
id: GO:0000070
name: mitotic sister chromatid segregation
alt_id: GO:0016359
namespace: biological_process
def: "The cell cycle process whereby replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets." [GOC:ai]
is_a: GO:0000819
relationship: OBO_REL:part_of GO:0007067
synonym: "mitotic chromosome segregation" EXACT []
synonym: "mitotic sister-chromatid adhesion release" NARROW []

[Term]
id: GO:0000072
name: M phase specific microtubule process
namespace: biological_process
def: "A microtubule-based process that occurs only during M phase of the cell cycle." [GOC:mah]
is_a: GO:0007017
relationship: OBO_REL:part_of GO:0000279
synonym: "M-phase specific microtubule process" EXACT []

[Term]
id: GO:0000073
name: spindle pole body separation
alt_id: GO:0030475
namespace: biological_process
def: "A largely uncharacterized process involving the release of duplicated spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane. Duplicated SPBs are connected by a bridge structure that may be severed in order to release the SPBs from one another. Following liberation, SPBs diffuse through the nuclear membrane until they are across from each other. SPB separation must take place in order for a bipolar mitotic spindle to assemble." [GOC:sgd_curators]
is_a: GO:0022402
relationship: OBO_REL:part_of GO:0051300
synonym: "spindle pole body separation (sensu Fungi)" EXACT []
synonym: "spindle pole body separation (sensu Saccharomyces)" NARROW []

[Term]
id: GO:0000075
name: cell cycle checkpoint
namespace: biological_process
def: "A point in the eukaryotic cell cycle where progress through the cycle can be halted until conditions are suitable for the cell to proceed to the next stage." [GOC:mah, ISBN:0815316194]
is_a: GO:0051726
xref: Reactome:212094
xref: Reactome:221853
xref: Reactome:230421
xref: Reactome:238463
xref: Reactome:245004
xref: Reactome:249905
xref: Reactome:252621
xref: Reactome:255806
xref: Reactome:259199
xref: Reactome:262557
xref: Reactome:265381
xref: Reactome:268515
xref: Reactome:274237
xref: Reactome:280705
xref: Reactome:282912
xref: Reactome:286730
xref: Reactome:69620

[Term]
id: GO:0000076
name: DNA replication checkpoint
namespace: biological_process
def: "A signal transduction based surveillance mechanism that prevents the initiation of mitosis until DNA replication is complete, thereby ensuring that progeny inherit a full complement of the genome." [GOC:rn, PMID:11728327, PMID:12537518]
is_a: GO:0031570
is_a: GO:0032297

[Term]
id: GO:0000077
name: DNA damage checkpoint
namespace: biological_process
def: "A signal transduction pathway, induced by DNA damage, that blocks cell cycle progression (in G1, G2 or metaphase) or slows the rate at which S phase proceeds." [PMID:11891124]
is_a: GO:0031570
is_a: GO:0042770
synonym: "DNA damage response, signal transduction resulting in cell cycle arrest" NARROW []

[Term]
id: GO:0000078
name: cell morphogenesis checkpoint
namespace: biological_process
def: "A cell cycle checkpoint observed when aspects of polarity control are defective, which maintains coordination between the process of cellular morphogenesis and the nuclear events of the cell cycle. For example, in budding yeast cell-cycle delay or arrest is induced when aspects of bud formation are defective." [GOC:vw, PMID:14644188]
is_a: GO:0007093
relationship: OBO_REL:part_of GO:0000902

[Term]
id: GO:0000079
name: regulation of cyclin-dependent protein kinase activity
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of CDK activity." [GOC:go_curators]
is_a: GO:0045859
is_a: GO:0051726
synonym: "regulation of CDK activity" EXACT []

[Term]
id: GO:0000080
name: G1 phase of mitotic cell cycle
namespace: biological_process
def: "Progression through G1 phase, one of two 'gap' phases in the mitotic cell cycle; G1 is the interval between the completion of mitosis and the beginning of DNA synthesis." [ISBN:0815316194]
is_a: GO:0051318
relationship: OBO_REL:part_of GO:0051329
xref: Reactome:212033
xref: Reactome:221797
xref: Reactome:230372
xref: Reactome:238411
xref: Reactome:69236

[Term]
id: GO:0000082
name: G1/S transition of mitotic cell cycle
namespace: biological_process
def: "Progression from G1 phase to S phase of the mitotic cell cycle." [GOC:mah]
is_a: GO:0022402
relationship: OBO_REL:part_of GO:0051329
xref: Reactome:212021
xref: Reactome:221784
xref: Reactome:230362
xref: Reactome:238403
xref: Reactome:244953
xref: Reactome:249850
xref: Reactome:252607
xref: Reactome:255745
xref: Reactome:259140
xref: Reactome:262495
xref: Reactome:265325
xref: Reactome:268498
xref: Reactome:274174
xref: Reactome:280647
xref: Reactome:282899
xref: Reactome:286666
xref: Reactome:288375
xref: Reactome:289876
xref: Reactome:290408
xref: Reactome:291794
xref: Reactome:293774
xref: Reactome:69206

[Term]
id: GO:0000083
name: G1/S-specific transcription in mitotic cell cycle
namespace: biological_process
def: "Any process that regulates transcription such that the target genes are transcribed during the G1/S phase of the mitotic cell cycle." [GOC:mah]
is_a: GO:0006357
is_a: GO:0022402
relationship: OBO_REL:part_of GO:0000082
xref: Reactome:69205

[Term]
id: GO:0000084
name: S phase of mitotic cell cycle
namespace: biological_process
def: "Progression through S phase, the part of the mitotic cell cycle during which DNA synthesis takes place." [ISBN:0815316194]
is_a: GO:0051320
relationship: OBO_REL:part_of GO:0051329

[Term]
id: GO:0000085
name: G2 phase of mitotic cell cycle
namespace: biological_process
def: "Progression through G2 phase, one of two 'gap' phases in the mitotic cell cycle; G2 is the interval between the completion of DNA synthesis and the beginning of mitosis." [ISBN:0815316194]
is_a: GO:0051319
relationship: OBO_REL:part_of GO:0051329
xref: Reactome:211891
xref: Reactome:221655
xref: Reactome:230246
xref: Reactome:238281
xref: Reactome:244852
xref: Reactome:249746
xref: Reactome:268392
xref: Reactome:274099
xref: Reactome:280573
xref: Reactome:68911

[Term]
id: GO:0000086
name: G2/M transition of mitotic cell cycle
namespace: biological_process
def: "Progression from G2 phase to M phase of the mitotic cell cycle." [GOC:mah]
is_a: GO:0022402
relationship: OBO_REL:part_of GO:0051329
xref: Reactome:211972
xref: Reactome:221737
xref: Reactome:230316
xref: Reactome:238398
xref: Reactome:244912
xref: Reactome:249804
xref: Reactome:252543
xref: Reactome:255721
xref: Reactome:259114
xref: Reactome:262473
xref: Reactome:265322
xref: Reactome:268466
xref: Reactome:274171
xref: Reactome:280644
xref: Reactome:282855
xref: Reactome:286663
xref: Reactome:69275

[Term]
id: GO:0000087
name: M phase of mitotic cell cycle
namespace: biological_process
def: "Progression through M phase, the part of the mitotic cell cycle during which mitosis takes place." [GOC:mah, ISBN:0815316194]
is_a: GO:0000279
relationship: OBO_REL:part_of GO:0000278
synonym: "M-phase of mitotic cell cycle" EXACT []
xref: Reactome:212043
xref: Reactome:221806
xref: Reactome:230379
xref: Reactome:238418
xref: Reactome:244995
xref: Reactome:249877
xref: Reactome:252596
xref: Reactome:255795
xref: Reactome:259176
xref: Reactome:262532
xref: Reactome:265359
xref: Reactome:268488
xref: Reactome:282892
xref: Reactome:286702
xref: Reactome:68886

[Term]
id: GO:0000088
name: mitotic prophase
namespace: biological_process
def: "Progression through prophase, the initial stage of mitosis in which the chromosomes are condensed but are not yet attached to a mitotic spindle." [ISBN:0815316194]
is_a: GO:0051324
relationship: OBO_REL:part_of GO:0007067
xref: Reactome:211977
xref: Reactome:221742
xref: Reactome:230322
xref: Reactome:238359
xref: Reactome:244917
xref: Reactome:249807
xref: Reactome:252546
xref: Reactome:255723
xref: Reactome:259116
xref: Reactome:262475
xref: Reactome:268434
xref: Reactome:286639
xref: Reactome:68875

[Term]
id: GO:0000089
name: mitotic metaphase
namespace: biological_process
def: "Progression through metaphase, the stage of mitosis at which chromosomes are firmly attached to the mitotic spindle at its equator but have not yet segregated to opposite poles." [ISBN:0815316194]
is_a: GO:0051323
relationship: OBO_REL:part_of GO:0007067
xref: Reactome:68879

[Term]
id: GO:0000090
name: mitotic anaphase
namespace: biological_process
def: "Progression through anaphase, the stage of mitosis during which the two sets of chromosomes separate and move away from each other." [ISBN:0815316194]
is_a: GO:0051322
relationship: OBO_REL:part_of GO:0007067
xref: Reactome:68882

[Term]
id: GO:0000091
name: mitotic anaphase A
namespace: biological_process
def: "Progression through anaphase A, the part of mitotic anaphase in which the kinetochore microtubules shorten as chromosomes move toward the spindle poles." [ISBN:0815316194]
is_a: GO:0000090

[Term]
id: GO:0000092
name: mitotic anaphase B
namespace: biological_process
def: "Progression through anaphase B, the part of mitotic anaphase in which the polar microtubules elongate and the two poles of the spindle move farther apart." [ISBN:0815316194]
is_a: GO:0000090

[Term]
id: GO:0000093
name: mitotic telophase
namespace: biological_process
def: "Progression through telophase, the last of the stages of mitosis; in the canonical cell cycle, telophase begins when the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts." [ISBN:0721662544 "Dorland's Illustrated Medical Dictionary"]
is_a: GO:0051326
relationship: OBO_REL:part_of GO:0007067

[Term]
id: GO:0000094
name: septin assembly and septum formation
namespace: biological_process
def: "OBSOLETE (was not defined before being made obsolete)." [GOC:go_curators]
comment: This term was made obsolete because it was not defined and the string name implied two separate processes.
is_obsolete: true
consider: GO:0000917
consider: GO:0000918
consider: GO:0000921

[Term]
id: GO:0000096
name: sulfur amino acid metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving amino acids containing sulfur, comprising cysteine, homocysteine, methionine and selenocysteine." [GOC:ai]
subset: gosubset_prok
is_a: GO:0006520
is_a: GO:0006790
synonym: "sulfur amino acid metabolism" EXACT []
synonym: "sulphur amino acid metabolic process" EXACT []
synonym: "sulphur amino acid metabolism" EXACT []

[Term]
id: GO:0000097
name: sulfur amino acid biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of amino acids containing sulfur, comprising cysteine, methionine and selenocysteine." [GOC:ai]
subset: gosubset_prok
is_a: GO:0000096
is_a: GO:0008652
is_a: GO:0044272
synonym: "sulfur amino acid anabolism" EXACT []
synonym: "sulfur amino acid biosynthesis" EXACT []
synonym: "sulfur amino acid formation" EXACT []
synonym: "sulfur amino acid synthesis" EXACT []
synonym: "sulphur amino acid biosynthesis" EXACT []
synonym: "sulphur amino acid biosynthetic process" EXACT []

[Term]
id: GO:0000098
name: sulfur amino acid catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of amino acids containing sulfur, comprising cysteine, methionine and selenocysteine." [GOC:ai]
subset: gosubset_prok
is_a: GO:0000096
is_a: GO:0009063
is_a: GO:0044273
synonym: "sulfur amino acid breakdown" EXACT []
synonym: "sulfur amino acid catabolism" EXACT []
synonym: "sulfur amino acid degradation" EXACT []
synonym: "sulphur amino acid catabolic process" EXACT []
synonym: "sulphur amino acid catabolism" EXACT []

[Term]
id: GO:0000101
name: sulfur amino acid transport
namespace: biological_process
def: "The directed movement of amino acids containing sulfur (cystine, methionine and their derivatives) into, out of, within or between cells." [GOC:ai]
subset: gosubset_prok
is_a: GO:0006865
synonym: "sulphur amino acid transport" EXACT []

[Term]
id: GO:0000103
name: sulfate assimilation
namespace: biological_process
def: "The pathways by which inorganic sulfate is processed and incorporated into sulfated compounds." [GOC:jl]
subset: gosubset_prok
is_a: GO:0006791
synonym: "sulphate assimilation" EXACT []

[Term]
id: GO:0000105
name: histidine biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid." [GOC:go_curators]
subset: gosubset_prok
is_a: GO:0006547
is_a: GO:0009076
synonym: "histidine anabolism" EXACT []
synonym: "histidine biosynthesis" EXACT []
synonym: "histidine formation" EXACT []
synonym: "histidine synthesis" EXACT []
xref: MetaCyc:HISTSYN-PWY

[Term]
id: GO:0000114
name: G1-specific transcription in mitotic cell cycle
namespace: biological_process
def: "Any process that regulates transcription such that the target genes are transcribed during the G1 phase of the mitotic cell cycle." [GOC:mah]
is_a: GO:0006357
is_a: GO:0022402
relationship: OBO_REL:part_of GO:0000080

[Term]
id: GO:0000115
name: S-phase-specific transcription in mitotic cell cycle
namespace: biological_process
def: "A cell cycle process that regulates transcription such that the target genes are transcribed during the S phase of the mitotic cell cycle." [GOC:mah]
is_a: GO:0006357
is_a: GO:0022402
relationship: OBO_REL:part_of GO:0000084
synonym: "S-specific transcription in mitotic cell cycle" EXACT []
xref: Reactome:69241

[Term]
id: GO:0000116
name: G2-specific transcription in mitotic cell cycle
namespace: biological_process
def: "Any process that regulates transcription such that the target genes are transcribed during the G2 phase of the mitotic cell cycle." [GOC:mah]
is_a: GO:0006357
is_a: GO:0022402
relationship: OBO_REL:part_of GO:0000085

[Term]
id: GO:0000117
name: G2/M-specific transcription in mitotic cell cycle
namespace: biological_process
def: "Any process that regulates transcription such that the target genes are transcribed during the G2/M phase of the mitotic cell cycle." [GOC:mah]
is_a: GO:0006357
is_a: GO:0022402
relationship: OBO_REL:part_of GO:0000086
xref: Reactome:69274

[Term]
id: GO:0000122
name: negative regulation of transcription from RNA polymerase II promoter
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:go_curators]
is_a: GO:0006357
is_a: GO:0045892
relationship: negatively_regulates GO:0006366
synonym: "down regulation of transcription from RNA polymerase II promoter" EXACT []
synonym: "down-regulation of transcription from RNA polymerase II promoter" EXACT []
synonym: "downregulation of transcription from RNA polymerase II promoter" EXACT []
synonym: "inhibition of transcription from RNA polymerase II promoter" NARROW []
synonym: "negative regulation of transcription from Pol II promoter" EXACT []

[Term]
id: GO:0000128
name: flocculation
namespace: biological_process
def: "The non-sexual aggregation of single-celled organisms." [GOC:jl]
subset: goslim_pir
subset: gosubset_prok
is_a: GO:0051704

[Term]
id: GO:0000132
name: establishment of mitotic spindle orientation
alt_id: GO:0030607
alt_id: GO:0030609
namespace: biological_process
def: "A cell cycle process that sets the alignment of mitotic spindle relative to other cellular structures." [GOC:ems]
is_a: GO:0040001
is_a: GO:0051294
synonym: "establishment of spindle orientation during mitosis" EXACT []
synonym: "mitotic spindle orientation" EXACT []
synonym: "mitotic spindle orientation (sensu Fungi)" NARROW []
synonym: "mitotic spindle orientation (sensu Saccharomyces)" NARROW []
synonym: "orienting of mitotic spindle" EXACT []

[Term]
id: GO:0000135
name: septin checkpoint
namespace: biological_process
def: "A cell cycle checkpoint that detects septin defects and responds by inhibiting the mitotic CDK. In Saccharomyces cerevisiae, correct formation of a functional septin cytoskeleton permits the cell to switch to isotropic bud growth and the onset of mitotic chromosome segregation. In the presence of septin defects, the mitotic CDK is inhibited and both the switch to isotropic bud growth and the onset of mitotic chromosome segregation is delayed." [PMID:9925642]
is_a: GO:0031565

[Term]
id: GO:0000147
name: actin cortical patch assembly
namespace: biological_process
def: "Assembly of an actin cortical patch, a discrete actin-containing structure found at the plasma membrane of fungal cells." [GOC:mah]
is_a: GO:0022607
is_a: GO:0030866

[Term]
id: GO:0000154
name: rRNA modification
alt_id: GO:0016548
namespace: biological_process
def: "The covalent alteration of one or more nucleotides within an rRNA molecule to produce an rRNA molecule with a sequence that differs from that coded genetically." [GOC:curators]
comment: The term 'RNA editing' (GO:0016547) was merged into 'RNA modification' (GO:0009451) on the basis of statements in the preface of Modification and Editing of RNA (ISBN:1555811337) that there is no clear distinction between modification and editing. Parallel changes were made for substrate (e.g. tRNA, rRNA, etc.) specific child terms of 'RNA editing'.
subset: gosubset_prok
is_a: GO:0006364
is_a: GO:0009451
synonym: "rRNA editing" EXACT []

[Term]
id: GO:0000160
name: two-component signal transduction system (phosphorelay)
namespace: biological_process
def: "A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins." [PMID:9191038]
subset: gosubset_prok
is_a: GO:0007165
synonym: "histidyl-aspartyl phosphorelay" EXACT []

[Term]
id: GO:0000161
name: MAPKKK cascade during osmolarity sensing
namespace: biological_process
def: "MAPKKK cascade involved in signal transduction in response to change in osmotic conditions." [PMID:9561267]
is_a: GO:0000165
relationship: OBO_REL:part_of GO:0007231
synonym: "osmolarity sensing, MAPKKK cascade" EXACT []

[Term]
id: GO:0000162
name: tryptophan biosynthetic process
alt_id: GO:0009096
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid; tryptophan is synthesized from chorismate via anthranilate." [GOC:mah, ISBN:0471331309 "Biochemical Pathways", MetaCyc:TRPSYN-PWY]
subset: gosubset_prok
is_a: GO:0006568
is_a: GO:0009073
is_a: GO:0046219
synonym: "aromatic amino acid family biosynthetic process, anthranilate pathway" EXACT []
synonym: "tryptophan anabolism" EXACT []
synonym: "tryptophan biosynthesis" EXACT []
synonym: "tryptophan formation" EXACT []
synonym: "tryptophan synthesis" EXACT []
xref: MetaCyc:TRPSYN-PWY

[Term]
id: GO:0000165
name: MAPKKK cascade
namespace: biological_process
def: "Cascade of at least three protein kinase activities culminating in the phosphorylation and activation of a MAP kinase. MAPKKK cascades lie downstream of numerous signaling pathways." [GOC:mah, PMID:9561267]
is_a: GO:0007243
synonym: "ERK/MAPK cascade" EXACT []
synonym: "MAP kinase cascade" EXACT []
synonym: "MAP kinase kinase kinase cascade" EXACT []
synonym: "MAPK cascade" EXACT []
synonym: "MAPK signaling" RELATED []
synonym: "MAPK signalling" RELATED []
synonym: "MAPKKK cascade during sporulation (sensu Fungi)" NARROW []
synonym: "MAPKKK cascade during sporulation (sensu Saccharomyces)" NARROW []
xref: Reactome:109869
xref: Reactome:211967
xref: Reactome:221732
xref: Reactome:230313
xref: Reactome:238351
xref: Reactome:244909
xref: Reactome:249802
xref: Reactome:252619
xref: Reactome:255804
xref: Reactome:259197
xref: Reactome:262555
xref: Reactome:268509
xref: Reactome:274234
xref: Reactome:280703
xref: Reactome:286727

[Term]
id: GO:0000167
name: activation of MAPKKK activity during osmolarity sensing
namespace: biological_process
def: "Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase during osmolarity sensing." [PMID:9561267]
is_a: GO:0000185
relationship: OBO_REL:part_of GO:0000161
synonym: "activation of MAP kinase kinase kinase activity during osmolarity sensing" EXACT []
synonym: "osmolarity sensing, activation of MAP kinase kinase kinase activity" EXACT []
synonym: "osmolarity sensing, activation of MAPKKK activity" EXACT []

[Term]
id: GO:0000168
name: activation of MAPKK activity during osmolarity sensing
alt_id: GO:0007233
namespace: biological_process
def: "Any process that initiates the activity of the inactive enzyme MAP kinase kinase during osmolarity sensing." [PMID:9561267]
is_a: GO:0000186
relationship: OBO_REL:part_of GO:0000161
synonym: "activation of MAP kinase kinase activity during osmolarity sensing" EXACT []
synonym: "activation of Pbs2 kinase" NARROW []
synonym: "osmolarity sensing, activation of MAP kinase kinase activity" EXACT []
synonym: "osmolarity sensing, activation of MAPKK activity" EXACT []

[Term]
id: GO:0000169
name: activation of MAPK activity during osmolarity sensing
namespace: biological_process
def: "Any process that initiates the activity of the inactive enzyme MAP kinase activity during osmolarity sensing." [PMID:9561267]
is_a: GO:0000187
relationship: OBO_REL:part_of GO:0000161
synonym: "osmolarity sensing, activation of MAPK activity" EXACT []

[Term]
id: GO:0000173
name: inactivation of MAPK activity during osmolarity sensing
namespace: biological_process
def: "Any process that terminates the activity of the active enzyme MAP kinase during osmolarity sensing." [PMID:9561267]
is_a: GO:0000188
relationship: OBO_REL:part_of GO:0000161
synonym: "osmolarity sensing, inactivation of MAPK" EXACT []
synonym: "osmolarity sensing, termination of MAPK activity" EXACT []
synonym: "termination of MAPK activity during osmolarity sensing" EXACT []

[Term]
id: GO:0000174
name: inactivation of MAPK (mating sensu Saccharomyces)
namespace: biological_process
def: "OBSOLETE. Downregulation of MAP kinase activity in the context of transduction of mating pheromone signal, as described for Saccharomyces." [PMID:9561267]
comment: This term was made obsolete because it is a gene product specific term.
is_obsolete: true
replaced_by: GO:0000750

[Term]
id: GO:0000183
name: chromatin silencing at rDNA
namespace: biological_process
def: "Repression of transcription of ribosomal DNA by the formation of heterochromatin." [PMID:10219245]
is_a: GO:0006342
synonym: "chromatin silencing at ribosomal DNA" EXACT []
synonym: "heterochromatic silencing at rDNA" EXACT []

[Term]
id: GO:0000184
name: nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
namespace: biological_process
def: "The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins." [GOC:krc, GOC:ma, PMID:10025395]
is_a: GO:0000956
synonym: "mRNA breakdown, nonsense-mediated decay" EXACT []
synonym: "mRNA catabolic process, nonsense-mediated" EXACT []
synonym: "mRNA catabolism, nonsense-mediated" EXACT []
synonym: "mRNA degradation, nonsense-mediated decay" EXACT []
synonym: "nonsense-mediated mRNA decay" EXACT []
synonym: "nuclear mRNA catabolic process, nonsense-mediated decay" EXACT []

[Term]
id: GO:0000185
name: activation of MAPKKK activity
namespace: biological_process
def: "Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase." [PMID:9561267]
is_a: GO:0032147
relationship: OBO_REL:part_of GO:0000165
synonym: "activation of MAP kinase kinase kinase" EXACT []
synonym: "activation of MAPKKK during sporulation (sensu Fungi)" NARROW []
synonym: "activation of MAPKKK during sporulation (sensu Saccharomyces)" NARROW []
synonym: "positive regulation of MAP kinase kinase kinase activity" BROAD []
synonym: "positive regulation of MAPKKK activity" BROAD []

[Term]
id: GO:0000186
name: activation of MAPKK activity
alt_id: GO:0007255
namespace: biological_process
def: "The initiation of the activity of the inactive enzyme MAP kinase kinase by phosphorylation by a MAPKKK." [PMID:9561267]
is_a: GO:0006468
is_a: GO:0032147
relationship: OBO_REL:part_of GO:0000165
synonym: "activation of MAP kinase kinase activity" EXACT []
synonym: "activation of MAP/ERK kinase kinase" EXACT []
synonym: "activation of MAPKK during sporulation (sensu Fungi)" NARROW []
synonym: "activation of MAPKK during sporulation (sensu Saccharomyces)" NARROW []
synonym: "positive regulation of MAPKK activity" BROAD []
xref: Reactome:110049
xref: Reactome:211601
xref: Reactome:221376
xref: Reactome:230014
xref: Reactome:238032
xref: Reactome:244648
xref: Reactome:249583

[Term]
id: GO:0000187
name: activation of MAPK activity
namespace: biological_process
def: "The initiation of the activity of the inactive enzyme MAP kinase by phosphorylation by a MAPKK." [PMID:9561267]
is_a: GO:0006468
is_a: GO:0043406
relationship: OBO_REL:part_of GO:0000165
synonym: "activation of MAP kinase" EXACT []
synonym: "activation of MAPK during sporulation (sensu Fungi)" NARROW []
synonym: "activation of MAPK during sporulation (sensu Saccharomyces)" NARROW []
synonym: "MAPK activation" EXACT []
xref: Reactome:112409
xref: Reactome:212039
xref: Reactome:221803
xref: Reactome:230377
xref: Reactome:238416
xref: Reactome:244963
xref: Reactome:249842
xref: Reactome:252574
xref: Reactome:255755
xref: Reactome:259149
xref: Reactome:262506
xref: Reactome:268461
xref: Reactome:274183
xref: Reactome:280656
xref: Reactome:286675

[Term]
id: GO:0000188
name: inactivation of MAPK activity
namespace: biological_process
def: "Any process that terminates the activity of the active enzyme MAP kinase." [PMID:9561267]
is_a: GO:0043407
relationship: OBO_REL:part_of GO:0000165
synonym: "inactivation of MAPK during sporulation (sensu Fungi)" NARROW []
synonym: "inactivation of MAPK during sporulation (sensu Saccharomyces)" NARROW []
synonym: "termination of MAPK activity" EXACT []

[Term]
id: GO:0000189
name: nuclear translocation of MAPK
namespace: biological_process
def: "The directed movement of a MAP kinase to the nucleus upon activation." [PMID:9561267]
is_a: GO:0000060
relationship: OBO_REL:part_of GO:0000165
xref: Reactome:109867
xref: Reactome:109868
xref: Reactome:112353
xref: Reactome:209891
xref: Reactome:209896
xref: Reactome:228348
xref: Reactome:228351
xref: Reactome:236568
xref: Reactome:236573
xref: Reactome:243599
xref: Reactome:243605
xref: Reactome:248698
xref: Reactome:248703
xref: Reactome:251790
xref: Reactome:251793
xref: Reactome:254938
xref: Reactome:254943
xref: Reactome:258208
xref: Reactome:258211
xref: Reactome:261726
xref: Reactome:261729
xref: Reactome:267714
xref: Reactome:267717
xref: Reactome:273179
xref: Reactome:273186
xref: Reactome:279660
xref: Reactome:279666
xref: Reactome:285768
xref: Reactome:285771

[Term]
id: GO:0000190
name: MAPKKK cascade (pseudohyphal growth)
namespace: biological_process
def: "OBSOLETE. MAPKKK cascade involved in transduction of signal promoting pseudohyphal or invasive growth." [PMID:9561267]
comment: This term was made obsolete because it is a gene product specific term.
is_obsolete: true

[Term]
id: GO:0000191
name: activation of MAPKKK (pseudohyphal growth)
namespace: biological_process
def: "OBSOLETE. Upregulation of MAPKKK activity in the context of regulating pseudohyphal or invasive growth." [PMID:9561267]
comment: This term was made obsolete because it is a gene product specific term.
is_obsolete: true

[Term]
id: GO:0000192
name: activation of MAPKK (pseudohyphal growth)
namespace: biological_process
def: "OBSOLETE. Upregulation of a MAP kinase kinase in the context of regulating pseudohyphal or invasive growth." [PMID:9561267]
comment: This term was made obsolete because it is a gene product specific term.
is_obsolete: true

[Term]
id: GO:0000193
name: activation of MAPK (pseudohyphal growth)
namespace: biological_process
def: "OBSOLETE. Upregulation of MAP kinase activity in the context of regulating pseudohyphal or invasive growth." [PMID:9561267]
comment: This term was made obsolete because it is a gene product specific term.
is_obsolete: true

[Term]
id: GO:0000194
name: inactivation of MAPK (pseudohyphal growth)
namespace: biological_process
def: "OBSOLETE. Downregulation of MAP kinase activity in the context of regulating pseudohyphal or invasive growth." [PMID:9561267]
comment: This term was made obsolete because it is a gene product specific term.
is_obsolete: true

[Term]
id: GO:0000195
name: nuclear translocation of MAPK (pseudohyphal growth)
namespace: biological_process
def: "OBSOLETE. Movement of a MAP kinase to the nucleus in the context of regulating pseudohyphal or invasive growth." [PMID:9561267]
comment: This term was made obsolete because it is a gene product specific term.
is_obsolete: true

[Term]
id: GO:0000196
name: MAPKKK cascade during cell wall biogenesis
namespace: biological_process
def: "Cascade of at least three protein kinase activities culminating in the phosphorylation and activation of a MAP kinase that occurs during cell wall biogenesis, the assembly and arrangement of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells." [PMID:9561267]
is_a: GO:0000165
relationship: OBO_REL:part_of GO:0007047
synonym: "cell wall biogenesis, MAPKKK cascade" EXACT []

[Term]
id: GO:0000197
name: activation of MAPKKK activity during cell wall biogenesis
namespace: biological_process
def: "Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase during cell wall biogenesis, the assembly and arrangement of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells." [PMID:9561267]
is_a: GO:0000185
relationship: OBO_REL:part_of GO:0000196
synonym: "activation of MAP kinase kinase kinase activity during cell wall biogenesis" EXACT []
synonym: "cell wall biogenesis, activation of MAP kinase kinase kinase activity" EXACT []
synonym: "cell wall biogenesis, activation of MAPKKK activity" EXACT []

[Term]
id: GO:0000198
name: activation of MAPKK activity during cell wall biogenesis
namespace: biological_process
def: "Any process that initiates the activity of the inactive enzyme MAP kinase kinase during cell wall biogenesis, the assembly and arrangement of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells." [PMID:9561267]
is_a: GO:0000186
relationship: OBO_REL:part_of GO:0000196
synonym: "activation of MAP kinase kinase activity during cell wall biogenesis" EXACT []
synonym: "cell wall biogenesis, activation of MAP kinase kinase activity" EXACT []
synonym: "cell wall biogenesis, activation of MAPKK activity" EXACT []

[Term]
id: GO:0000199
name: activation of MAPK activity during cell wall biogenesis
namespace: biological_process
def: "Any process that initiates the activity of the inactive enzyme MAP kinase during cell wall biogenesis, the assembly and arrangement of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells." [PMID:9561267]
is_a: GO:0000187
relationship: OBO_REL:part_of GO:0000196
synonym: "cell wall biogenesis, activation of MAPK activity" EXACT []

[Term]
id: GO:0000200
name: inactivation of MAPK activity during cell wall biogenesis
namespace: biological_process
def: "Any process that terminates the activity of the active enzyme MAP kinase during cell wall biogenesis, the assembly and arrangement of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells." [PMID:9561267]
is_a: GO:0000188
relationship: OBO_REL:part_of GO:0000196
synonym: "cell wall biogenesis, inactivation of MAPK activity" EXACT []
synonym: "cell wall biogenesis, termination of MAPK activity" EXACT []
synonym: "termination of MAPK activity during cell wall biogenesis" EXACT []

[Term]
id: GO:0000201
name: nuclear translocation of MAPK during cell wall biogenesis
namespace: biological_process
def: "The directed movement of a MAP kinase to the nucleus during cell wall biogenesis, the assembly and arrangement of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells." [PMID:9561267]
is_a: GO:0000189
relationship: OBO_REL:part_of GO:0000196
synonym: "cell wall biogenesis, nuclear translocation of MAPK" EXACT []

[Term]
id: GO:0000202
name: MAPKKK cascade during sporulation (sensu Saccharomyces)
namespace: biological_process
def: "OBSOLETE. MAPKKK cascade involved in transduction of signal promoting sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930)." [PMID:9561267]
comment: This term was made obsolete because it is a gene product specific term.
is_obsolete: true

[Term]
id: GO:0000203
name: activation of MAPKKK during sporulation (sensu Saccharomyces)
namespace: biological_process
def: "OBSOLETE. Upregulation of MAPKKK activity in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930)." [PMID:9561267]
comment: This term was made obsolete because it is a gene product specific term.
is_obsolete: true

[Term]
id: GO:0000204
name: activation of MAPKK during sporulation (sensu Saccharomyces)
namespace: biological_process
def: "OBSOLETE. Upregulation of a MAP kinase kinase in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930)." [PMID:9561267]
comment: This term was made obsolete because it is a gene product specific term.
is_obsolete: true

[Term]
id: GO:0000205
name: activation of MAPK during sporulation (sensu Saccharomyces)
namespace: biological_process
def: "OBSOLETE. Upregulation of MAP kinase activity in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930)." [PMID:9561267]
comment: This term was made obsolete because it is a gene product specific term.
is_obsolete: true

[Term]
id: GO:0000206
name: inactivation of MAPK during sporulation (sensu Saccharomyces)
namespace: biological_process
def: "OBSOLETE. Downregulation of MAP kinase activity in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930)." [PMID:9561267]
comment: This term was made obsolete because it is a gene product specific term.
is_obsolete: true

[Term]
id: GO:0000207
name: nuclear translocation of MAPK during sporulation (sensu Saccharomyces)
namespace: biological_process
def: "OBSOLETE. Movement of a MAP kinase to the nucleus in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930)." [PMID:9561267]
comment: This term was made obsolete because it is a gene product specific term.
is_obsolete: true

[Term]
id: GO:0000208
name: nuclear translocation of MAPK during osmolarity sensing
namespace: biological_process
def: "The directed movement of a MAP kinase to the nucleus during osmolarity sensing." [PMID:9561267]
is_a: GO:0000189
relationship: OBO_REL:part_of GO:0000161
synonym: "osmolarity sensing, nuclear translocation of MAPK" EXACT []

[Term]
id: GO:0000209
name: protein polyubiquitination
namespace: biological_process
def: "Addition of multiple ubiquitin moieties to a protein, forming a ubiquitin chain." [ISBN:0815316194]
is_a: GO:0016567
synonym: "polyubiquitin" RELATED []
synonym: "protein polyubiquitinylation" EXACT []
synonym: "protein polyubiquitylation" EXACT []

[Term]
id: GO:0000212
name: meiotic spindle organization and biogenesis
namespace: biological_process
def: "A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of the microtubule spindle during a meiotic cell cycle." [GOC:mah]
is_a: GO:0007051
is_a: GO:0022402
relationship: OBO_REL:part_of GO:0051321
synonym: "meiotic spindle organisation and biogenesis" EXACT []
synonym: "spindle organization and biogenesis during meiosis" EXACT []

[Term]
id: GO:0000216
name: M/G1 transition of mitotic cell cycle
namespace: biological_process
def: "Progression from M phase to G1 phase of the mitotic cell cycle." [GOC:mah]
is_a: GO:0022402
relationship: OBO_REL:part_of GO:0051329
xref: Reactome:211997
xref: Reactome:221761
xref: Reactome:230342
xref: Reactome:238378
xref: Reactome:244933
xref: Reactome:249898
xref: Reactome:252623
xref: Reactome:255800
xref: Reactome:259165
xref: Reactome:262551
xref: Reactome:265375
xref: Reactome:274161
xref: Reactome:280634
xref: Reactome:286652
xref: Reactome:68874

[Term]
id: GO:0000226
name: microtubule cytoskeleton organization and biogenesis
namespace: biological_process
def: "A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins." [GOC:mah]
is_a: GO:0007017

[Term]
id: GO:0000236
name: mitotic prometaphase
namespace: biological_process
def: "Progression through prometaphase, the stage following prophase in mitosis (in higher eukaryotes) during which the nuclear envelope is disrupted and breaks into membrane vesicles, and the spindle microtubules enter the nuclear region. Kinetochores mature on each centromere and attach to some of the spindle microtubules. Kinetochore microtubules begin the process of aligning chromosomes in one plane halfway between the poles." [GOC:mah, ISBN:0198547684]
is_a: GO:0022403
relationship: OBO_REL:part_of GO:0007067
xref: Reactome:68877

[Term]
id: GO:0000237
name: leptotene
namespace: biological_process
def: "Progression through the first stage of prophase I in meiosis, in which chromosomes first become visible." [ISBN:0198547684]
is_a: GO:0022403
relationship: OBO_REL:part_of GO:0007128

[Term]
id: GO:0000238
name: zygotene
namespace: biological_process
def: "Progression through the second stage of prophase I in meiosis, in which each chromosome pairs with its homolog; the two become aligned and crossing over may occur." [ISBN:0198547684]
is_a: GO:0022403
relationship: OBO_REL:part_of GO:0007128

[Term]
id: GO:0000239
name: pachytene
namespace: biological_process
def: "Progression through the third stage of prophase I in meiosis, in which crossing over occurs between a chromatid in one partner and another chromatid in the homologous chromosome." [ISBN:0198547684]
is_a: GO:0022403
relationship: OBO_REL:part_of GO:0007128

[Term]
id: GO:0000240
name: diplotene
namespace: biological_process
def: "Progression through the fourth stage of prophase I in meiosis, in which the homologous chromosomes begin to separate and the synaptonemal complex dissolves." [ISBN:0198547684]
is_a: GO:0022403
relationship: OBO_REL:part_of GO:0007128

[Term]
id: GO:0000241
name: diakinesis
namespace: biological_process
def: "Progression through the final stage of prophase I in meiosis; the transition to meiotic metaphase I." [ISBN:0198547684]
is_a: GO:0022403
relationship: OBO_REL:part_of GO:0007128

[Term]
id: GO:0000244
name: assembly of spliceosomal tri-snRNP
alt_id: GO:0000351
alt_id: GO:0000355
namespace: biological_process
def: "The formation of a tri-snRNP complex containing U4 and U6 (or U4atac and U6atac) snRNAs and U5 snRNAs and associated proteins. This includes reannealing of U4 and U6 (or U4atac and U6atac) snRNAs released from previous rounds of splicing to reform the U4/U6 snRNP (or U4atac/U6atac snRNP) as well as the subsequent association of the U5 snRNP with the U4/U6 snRNP (or U4atac/U6atac snRNP) to form a tri-snRNP that is ready to reassemble into another spliceosome complex." [ISBN:0879695897, PMID:9452384]
is_a: GO:0022618
relationship: OBO_REL:part_of GO:0000387
synonym: "assembly of spliceosomal tri-snRNP U4/U6.U5" NARROW []
synonym: "assembly of spliceosomal tri-snRNP U4atac/U6atac.U5" NARROW []
synonym: "snRNP recycling" BROAD []
synonym: "spliceosomal tri-snRNP assembly" EXACT []
synonym: "spliceosomal tri-snRNP U4/U6.U5 assembly" NARROW []
synonym: "spliceosomal tri-snRNP U4atac/U6atac.U5 assembly" NARROW []

[Term]
id: GO:0000245
name: spliceosome assembly
namespace: biological_process
def: "The aggregation, arrangement and bonding together of the spliceosome, a ribonucleoprotein apparatus that catalyzes nuclear mRNA splicing via transesterification reactions." [PMID:9476892]
is_a: GO:0022618
relationship: OBO_REL:part_of GO:0000398

[Term]
id: GO:0000255
name: allantoin metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving allantoin, (2,5-dioxo-4-imidazolidinyl)urea, an intermediate or end product of purine catabolism." [GOC:mah, ISBN:0198547684]
subset: gosubset_prok
is_a: GO:0009308
is_a: GO:0046483
synonym: "allantoin metabolism" EXACT []

[Term]
id: GO:0000256
name: allantoin catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of allantoin, (2,5-dioxo-4-imidazolidinyl)urea." [GOC:mah, ISBN:0198547684]
subset: gosubset_prok
is_a: GO:0000255
is_a: GO:0046700
synonym: "allantoin breakdown" EXACT []
synonym: "allantoin catabolism" EXACT []
synonym: "allantoin degradation" EXACT []

[Term]
id: GO:0000266
name: mitochondrial fission
namespace: biological_process
def: "The division of a mitochondrion within a cell to form two or more separate mitochondrial compartments." [PMID:11038192]
is_a: GO:0007005
is_a: GO:0048285
synonym: "mitochondrial division" EXACT []
synonym: "mitochondrial proliferation" RELATED []

[Term]
id: GO:0000270
name: peptidoglycan metabolic process
alt_id: GO:0009284
namespace: biological_process
def: "The chemical reactions and pathways involving peptidoglycans, any of a class of glycoconjugates found only in bacterial cell walls and consisting of strands of glycosaminoglycan cross-linked by oligopeptides to form a huge and rigid network." [URL:http://www.dsmz.de/species/murein.htm, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"]
subset: gosubset_prok
is_a: GO:0005975
synonym: "murein metabolic process" EXACT []
synonym: "murein metabolism" EXACT []
synonym: "peptidoglycan metabolism" EXACT []

[Term]
id: GO:0000271
name: polysaccharide biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of polysaccharides, polymers of more than 10 monosaccharide residues joined by glycosidic linkages." [GOC:go_curators]
subset: gosubset_prok
is_a: GO:0016051
is_a: GO:0043284
synonym: "glycan biosynthesis" EXACT []
synonym: "glycan biosynthetic process" EXACT []
synonym: "polysaccharide anabolism" EXACT []
synonym: "polysaccharide biosynthesis" EXACT []
synonym: "polysaccharide formation" EXACT []
synonym: "polysaccharide synthesis" EXACT []

[Term]
id: GO:0000272
name: polysaccharide catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of polysaccharides, polymers of more than 10 monosaccharide residues joined by glycosidic linkages." [GOC:go_curators]
subset: gosubset_prok
is_a: GO:0005976
is_a: GO:0043285
synonym: "polysaccharide breakdown" EXACT []
synonym: "polysaccharide catabolism" EXACT []
synonym: "polysaccharide degradation" EXACT []

[Term]
id: GO:0000273
name: lipoic acid metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving lipoic acid, 1,2-dithiolane-3-pentanoic acid, a coenzyme involved in oxidative decarboxylation of keto acids." [GOC:ai, URL:http://cancerweb.ncl.ac.uk/]
subset: gosubset_prok
is_a: GO:0006732
is_a: GO:0019752
is_a: GO:0046483
synonym: "lipoic acid metabolism" EXACT []

[Term]
id: GO:0000278
name: mitotic cell cycle
namespace: biological_process
def: "Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent." [GOC:mah, ISBN:0815316194, Reactome:69278]
is_a: GO:0007049
xref: Reactome:212083
xref: Reactome:221841
xref: Reactome:230408
xref: Reactome:238450
xref: Reactome:244991
xref: Reactome:249871
xref: Reactome:252608
xref: Reactome:255794
xref: Reactome:259188
xref: Reactome:262544
xref: Reactome:265374
xref: Reactome:268486
xref: Reactome:274210
xref: Reactome:280680
xref: Reactome:282900
xref: Reactome:286715
xref: Reactome:288392
xref: Reactome:289890
xref: Reactome:290421
xref: Reactome:291802
xref: Reactome:293782
xref: Reactome:69278

[Term]
id: GO:0000279
name: M phase
namespace: biological_process
def: "Progression through M phase, the part of the cell cycle comprising nuclear division." [ISBN:0815316194]
is_a: GO:0022403
synonym: "M-phase" EXACT []

[Term]
id: GO:0000280
name: nuclear division
namespace: biological_process
def: "The partitioning of the nucleus and its genetic information." [GOC:bf, GOC:jl, URL:http://www.biology-online.org/]
subset: goslim_pir
is_a: GO:0009987
synonym: "karyokinesis" RELATED []

[Term]
id: GO:0000281
name: cytokinesis after mitosis
namespace: biological_process
def: "A cell cycle process that results in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells." [GOC:ai]
is_a: GO:0033205

[Term]
id: GO:0000282
name: cellular bud site selection
namespace: biological_process
def: "The specification of the site where a daughter cell will form, in organisms that reproduce by budding." [GOC:mah]
comment: Note that this term was split from 'bud site selection/establishment of cell polarity (sensu Saccharomyces) ; GO:0007115' (sibling term 'establishment of cell polarity (sensu Saccharomyces) ; GO:0000283').
is_a: GO:0007105
is_a: GO:0030010
synonym: "bud site selection/establishment of cell polarity (sensu Saccharomyces)" BROAD []

[Term]
id: GO:0000284
name: shmoo orientation
namespace: biological_process
def: "OBSOLETE (was not defined before being made obsolete)." [GOC:elh]
comment: This term was made obsolete because it is an organism specific term. The entire branch of the ontology was reorganized to be more generally applicable.
is_obsolete: true
replaced_by: GO:0000753

[Term]
id: GO:0000288
name: nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
namespace: biological_process
def: "A major pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of ordered steps: poly(A) tail shortening, deadenylylation-dependent decapping, and decay of the transcript body, and that can regulate mRNA stability." [GOC:krc]
is_a: GO:0000956
synonym: "deadenylation-dependent mRNA decay" EXACT []
synonym: "mRNA breakdown, deadenylation-dependent decay" EXACT []
synonym: "mRNA catabolic process, deadenylation-dependent" EXACT []
synonym: "mRNA catabolic process, deadenylylation-dependent" EXACT []
synonym: "mRNA catabolism, deadenylation-dependent" EXACT []
synonym: "mRNA catabolism, deadenylylation-dependent" EXACT []
synonym: "mRNA degradation, deadenylation-dependent decay" EXACT []
synonym: "nuclear mRNA catabolic process, deadenylation-dependent decay" EXACT []

[Term]
id: GO:0000289
name: nuclear-transcribed mRNA poly(A) tail shortening
namespace: biological_process
def: "Shortening of the poly(A) tail of a nuclear-transcribed mRNA from full length to an oligo(A) length." [GOC:krc]
is_a: GO:0000956
relationship: OBO_REL:part_of GO:0000288
synonym: "3' to 5' mRNA deadenylation" RELATED []
synonym: "mRNA deadenylation" RELATED []
synonym: "nuclear mRNA poly(A) tail shortening" RELATED []

[Term]
id: GO:0000290
name: deadenylation-dependent decapping of nuclear-transcribed mRNA
namespace: biological_process
def: "Cleavage of the 5'-cap of a nuclear mRNA triggered by shortening of the poly(A) tail to below a minimum functional length." [GOC:krc]
is_a: GO:0000956
relationship: OBO_REL:part_of GO:0000288
synonym: "deadenylation-dependent decapping of nuclear mRNA" EXACT []
synonym: "deadenylylation-dependent decapping" EXACT []

[Term]
id: GO:0000291
name: nuclear-transcribed mRNA catabolic process, exonucleolytic
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs when the ends are not protected by the 5'-cap or the 3'-poly(A) tail." [GOC:krc]
is_a: GO:0000956
relationship: OBO_REL:part_of GO:0000288
relationship: OBO_REL:part_of GO:0000294
synonym: "exonucleolytic degradation of mRNA" EXACT []
synonym: "mRNA breakdown, exonucleolytic" EXACT []
synonym: "mRNA degradation, exonucleolytic" EXACT []
synonym: "nuclear mRNA catabolic process, exonucleolytic" EXACT []

[Term]
id: GO:0000292
name: RNA fragment catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of a fragment of RNA, such as excised introns or sequences removed from ribosomal RNA during processing." [GOC:mah]
subset: gosubset_prok
is_a: GO:0006401
synonym: "RNA fragment breakdown" EXACT []
synonym: "RNA fragment catabolism" EXACT []
synonym: "RNA fragment degradation" EXACT []

[Term]
id: GO:0000294
name: nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay
namespace: biological_process
def: "A minor degradation pathway nuclear-transcribed mRNAs that begins with an endonucleolytic cleavage to generate unprotected ends." [GOC:krc]
is_a: GO:0000956
synonym: "endonucleolytic mRNA decay" EXACT []
synonym: "mRNA breakdown, endonucleolytic cleavage-dependent decay" EXACT []
synonym: "mRNA catabolic process, endonucleolytic" EXACT []
synonym: "mRNA catabolism, endonucleolytic" EXACT []
synonym: "mRNA degradation, endonucleolytic cleavage-dependent decay" EXACT []
synonym: "nuclear mRNA catabolic process, endonucleolytic cleavage-dependent decay" EXACT []

[Term]
id: GO:0000296
name: spermine transport
namespace: biological_process
def: "The directed movement of spermine, N,N-bis(3-aminopropyl)-1,4-diaminobutane, a polyamine formed by the transfer of a propylamine group from decarboxylated S-adenosylmethionine to spermidine, into, out of, within or between cells." [GOC:krc, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"]
is_a: GO:0015846

[Term]
id: GO:0000301
name: retrograde transport, vesicle recycling within Golgi
namespace: biological_process
def: "The retrograde movement of substances within the Golgi, mediated by COP I vesicles. Cis-Golgi vesicles are constantly moving forward through the Golgi stack by cisternal progression, eventually becoming trans-Golgi vesicles. They then selectively transport membrane and luminal proteins from the trans- to the medial-Golgi while leaving others behind in the trans-Golgi cisternae; similarly, they selectively move proteins from the medial- to the cis-Golgi." [ISBN:0716731363]
is_a: GO:0006891
synonym: "retrograde (vesicle recycling within Golgi) transport" EXACT []

[Term]
id: GO:0000302
name: response to reactive oxygen species
namespace: biological_process
def: "A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals." [GOC:krc]
subset: gosubset_prok
is_a: GO:0006979
synonym: "response to active oxygen species" EXACT []
synonym: "response to AOS" EXACT []
synonym: "response to reactive oxidative species" EXACT []
synonym: "response to reactive oxygen intermediate" EXACT []
synonym: "response to ROI" EXACT []
synonym: "response to ROS" EXACT []

[Term]
id: GO:0000303
name: response to superoxide
namespace: biological_process
def: "A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a superoxide stimulus. Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion." [GOC:krc, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"]
subset: gosubset_prok
is_a: GO:0000305

[Term]
id: GO:0000304
name: response to singlet oxygen
namespace: biological_process
def: "A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a singlet oxygen stimulus. Singlet oxygen is a dioxygen (O2) molecule in which two 2p electrons have similar spin. Singlet oxygen is more highly reactive than the form in which these electrons are of opposite spin, and it is produced in mutant chloroplasts lacking carotenoids and by leukocytes during metabolic burst." [GOC:krc, ISBN:0124325653, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"]
subset: gosubset_prok
is_a: GO:0000302

[Term]
id: GO:0000305
name: response to oxygen radical
namespace: biological_process
def: "A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen radical stimulus. An oxygen radical is any oxygen species that carries a free electron; examples include hydroxyl radicals and the superoxide anion." [GOC:krc, ISBN:0124325653]
subset: gosubset_prok
is_a: GO:0000302

[Term]
id: GO:0000316
name: sulfite transport
namespace: biological_process
def: "The directed movement of sulfite into, out of, within or between cells." [GOC:krc]
is_a: GO:0015698
synonym: "sulphite transport" EXACT []

[Term]
id: GO:0000320
name: re-entry into mitotic cell cycle
namespace: biological_process
def: "The resumption of the mitotic cell division cycle by cells that were in a quiescent or other non-dividing state." [GOC:krc]
is_a: GO:0022402

[Term]
id: GO:0000321
name: re-entry into mitotic cell cycle after pheromone arrest
namespace: biological_process
def: "The resumption of the mitotic cell division cycle by pheromone-arrested cells that have not mated." [GOC:krc, PMID:9927449]
is_a: GO:0000320
is_a: GO:0000754
synonym: "re-entry into mitotic cell cycle after pheromone arrest (sensu Saccharomyces)" NARROW []

[Term]
id: GO:0000335
name: negative regulation of transposition, DNA-mediated
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of DNA transposition." [GOC:dph, GOC:krc, GOC:tb]
subset: gosubset_prok
is_a: GO:0000337
is_a: GO:0010529
relationship: negatively_regulates GO:0006313
synonym: "down regulation of DNA transposition" EXACT []
synonym: "down-regulation of DNA transposition" EXACT []
synonym: "downregulation of DNA transposition" EXACT []
synonym: "inhibition of DNA transposition" NARROW []
synonym: "negative regulation of DNA transposition" EXACT [GOC:dph]

[Term]
id: GO:0000336
name: positive regulation of transposition, DNA-mediated
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of DNA transposition." [GOC:dph, GOC:krc]
subset: gosubset_prok
is_a: GO:0000337
is_a: GO:0010530
relationship: positively_regulates GO:0006313
synonym: "activation of DNA transposition" NARROW []
synonym: "positive regulation of DNA transposition" EXACT [GOC:dph]
synonym: "stimulation of DNA transposition" NARROW []
synonym: "up regulation of DNA transposition" EXACT []
synonym: "up-regulation of DNA transposition" EXACT []
synonym: "upregulation of DNA transposition" EXACT []

[Term]
id: GO:0000337
name: regulation of transposition, DNA-mediated
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of DNA transposition, the process of transposing (moving to a different location) a segment of a chromosome or a piece of a DNA molecule." [GOC:dph, GOC:krc]
subset: gosubset_prok
is_a: GO:0010528
relationship: regulates GO:0006313
synonym: "regulation of DNA transposition" EXACT [GOC:dph]

[Term]
id: GO:0000338
name: protein deneddylation
namespace: biological_process
def: "The removal of a ubiquitin-like protein of the NEDD8 type from a protein." [GOC:krc]
is_a: GO:0043687

[Term]
id: GO:0000348
name: nuclear mRNA branch site recognition
alt_id: GO:0000370
alt_id: GO:0000371
namespace: biological_process
def: "Recognition of the pre-mRNA branch site sequence by components of the assembling spliceosome." [GOC:krc, ISBN:0879695897]
comment: Note that this step represents the formation of the B complex (yeast) or the A complex (mammalian).
is_a: GO:0022618
relationship: OBO_REL:part_of GO:0000245
synonym: "spliceosomal A complex biosynthesis" NARROW []
synonym: "spliceosomal A complex formation" NARROW []
synonym: "spliceosomal B complex biosynthesis" NARROW []
synonym: "spliceosomal B complex formation" NARROW []
synonym: "U12-type nuclear mRNA branch site recognition" NARROW []
synonym: "U2-type nuclear mRNA branch site recognition" NARROW []

[Term]
id: GO:0000349
name: generation of catalytic spliceosome for first transesterification step
alt_id: GO:0000356
alt_id: GO:0000357
namespace: biological_process
def: "Formation of a catalytic spliceosome complex ready to perform the first splicing reaction. This occurs by an ATP-dependent conformational change of the pre-catalytic spliceosome." [GOC:krc, ISBN:0879695897]
comment: Note that this step represents the formation of the A2-2 complex (yeast) or the C1 complex (mammalian).
is_a: GO:0022618
relationship: OBO_REL:part_of GO:0000393
synonym: "catalytic spliceosome assembly for first transesterification step" RELATED []
synonym: "formation of catalytic spliceosome for first transesterification step" EXACT []
synonym: "spliceosomal A2-2 complex biosynthesis" NARROW []
synonym: "spliceosomal A2-2 complex formation" NARROW []
synonym: "spliceosomal C1 complex biosynthesis" NARROW []
synonym: "spliceosomal C1 complex formation" NARROW []
synonym: "U12-type catalytic spliceosome formation for first transesterification step" NARROW []
synonym: "U2-type catalytic spliceosome formation for first transesterification step" NARROW []

[Term]
id: GO:0000350
name: generation of catalytic spliceosome for second transesterification step
alt_id: GO:0000358
alt_id: GO:0000359
namespace: biological_process
def: "Conformational rearrangement of the spliceosomal complex containing the RNA products from the 1st step of splicing to form the catalytic site for the second step of splicing." [GOC:krc, ISBN:0879695897]
comment: Note that this step represents formation of the A2-3 complex (yeast) or the C2 complex (mammalian).
is_a: GO:0022618
relationship: OBO_REL:part_of GO:0000393
synonym: "catalytic spliceosome assembly for second transesterification step" RELATED []
synonym: "formation of catalytic spliceosome for second transesterification step" EXACT []
synonym: "formation of catalytic U12-type spliceosome for second transesterification step" NARROW []
synonym: "formation of catalytic U2-type spliceosome for second transesterification step" NARROW []
synonym: "formation of spliceosomal A2-2 complex" NARROW []
synonym: "formation of spliceosomal C1 complex" NARROW []
synonym: "lariat formation, 5'-splice site cleavage" RELATED []
synonym: "spliceosomal A2-3 complex biosynthesis" NARROW []
synonym: "spliceosomal A2-3 complex formation" NARROW []
synonym: "spliceosomal C2 complex biosynthesis" NARROW []
synonym: "spliceosomal C2 complex formation" NARROW []

[Term]
id: GO:0000352
name: trans assembly of SL containing precatalytic spliceosome
namespace: biological_process
def: "Assembly of a spliceosomal complex containing the SL RNA and the pre-mRNA to be joined, as well as all the spliceosomal snRNPs involved in trans leader splicing. Formation of the trans leader spliceosome brings together the quadruple SL/U4/U5/U6 snRNP and the complex of the U2 snRNP with the splice site of the pre-mRNA." [GOC:krc, ISBN:0879695897]
is_a: GO:0022618
relationship: OBO_REL:part_of GO:0000245
relationship: OBO_REL:part_of GO:0045291

[Term]
id: GO:0000353
name: formation of quadruple SL/U4/U5/U6 snRNP
namespace: biological_process
def: "Formation of a quadruple snRNP complex composed of the spliced leader (SL) RNA along with the U4/U6-U5 tri-snRNP complex. Interactions that may facilitate this include a duplex between the SL and U6 RNAs and interactions between the U5 RNA and the exon sequence at the 5' splice site within the SL RNA." [GOC:krc, ISBN:0879695897]
comment: Note that this step is analogous to 5' splice site selection in cis-splicing.
is_a: GO:0022618
relationship: OBO_REL:part_of GO:0045291

[Term]
id: GO:0000354
name: cis assembly of pre-catalytic spliceosome
alt_id: GO:0000360
alt_id: GO:0000361
namespace: biological_process
def: "Assembly of a spliceosomal complex containing the intact pre-mRNA and all of the spliceosomal snRNPs. This occurs when the tri-snRNP associates with the pre-mRNA and associated snRNPs in an ATP-dependent manner." [GOC:krc, ISBN:0879695897]
comment: Note that this step represents formation of the A2-1 complex (yeast) or the B1 complex (mammals).
is_a: GO:0022618
relationship: OBO_REL:part_of GO:0000245
relationship: OBO_REL:part_of GO:0045292
synonym: "cis assembly of U12-type pre-catalytic spliceosome" NARROW []
synonym: "cis assembly of U2-type pre-catalytic spliceosome" NARROW []
synonym: "formation of spliceosomal A2-1 complex" NARROW []
synonym: "formation of spliceosomal B1 complex" NARROW []
synonym: "spliceosomal A2-1 complex biosynthesis" NARROW []
synonym: "spliceosomal A2-1 complex formation" NARROW []
synonym: "spliceosomal B1 complex biosynthesis" NARROW []
synonym: "spliceosomal B1 complex formation" NARROW []

[Term]
id: GO:0000365
name: nuclear mRNA trans splicing, via spliceosome
namespace: biological_process
def: "The joining together of exons from two different primary transcripts of messenger RNA (mRNA) via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced." [GOC:krc, ISBN:0879695897]
is_a: GO:0000398
synonym: "nuclear mRNA trans splicing, via U2-type spliceosome" NARROW []

[Term]
id: GO:0000366
name: intergenic nuclear mRNA trans splicing
namespace: biological_process
def: "The joining together of two independently transcribed RNAs from two different genes, each of which also produces mRNA(s) via cis-splicing." [GOC:krc, PMID:11726664, PMID:12110900]
is_a: GO:0000365
is_a: GO:0000380

[Term]
id: GO:0000372
name: Group I intron splicing
namespace: biological_process
def: "The splicing of Group I introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group I introns and involved in determining the locations of the splice sites (there do not appear to be consensu thes splice site sequences) as well as having a role in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions, generally with exogenous guanosine as the initiating nucleophile. The intron is excised as a linear piece (though it may subsequently circularize)." [GOC:krc, PMID:11377794]
comment: Note that Group I introns are known to be found in a number of places: rRNA, mRNA, and tRNA in organelles of fungi, plants, and protists; tRNA and mRNA of bacteria and bacteriophage; rRNA of protists and fungi; and occasionally in mRNA of animal mitochondria (e.g. sea anemone).
subset: gosubset_prok
is_a: GO:0000376
synonym: "mRNA splicing" NARROW []

[Term]
id: GO:0000373
name: Group II intron splicing
namespace: biological_process
def: "The splicing of Group II introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group II introns and containing splice site consensu thes sequences, that is involved in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions (mechanistically similar to those for splicing of nuclear mRNAs) initiated by a bulged adenosine residue within the intron sequence as the initiating nucleophile. The intron is excised as a lariat." [GOC:krc, PMID:11377794]
comment: Note that Group II introns are known to be found in a number of places: rRNA, mRNA, and tRNA in organelles of fungi, plants, and protists; and mRNA of bacteria.
subset: gosubset_prok
is_a: GO:0000377
synonym: "mRNA splicing" NARROW []

[Term]
id: GO:0000374
name: Group III intron splicing
namespace: biological_process
def: "The splicing of Group III introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group III introns, that is involved in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions begun by a bulged adenosine residue within the intron sequence as the initiating nucleophile. The intron is excised as a lariat. Though very similar in structure and mechanism to Group II introns, Group III introns are smaller and more streamlined and the splice site consensu thes sequences are not as well conserved." [GOC:krc, PMID:11377794]
comment: Note that Group III introns are known to be found in mRNA of plastids of euglenoid protists.
subset: gosubset_prok
is_a: GO:0000377
synonym: "mRNA splicing" NARROW []

[Term]
id: GO:0000375
name: RNA splicing, via transesterification reactions
namespace: biological_process
def: "Splicing of RNA via a series of two transesterification reactions." [GOC:krc]
subset: gosubset_prok
is_a: GO:0008380

[Term]
id: GO:0000376
name: RNA splicing, via transesterification reactions with guanosine as nucleophile
namespace: biological_process
def: "Splicing of RNA via a series of two transesterification reactions with exogenous guanosine as the initiating nucleophile." [GOC:krc, PMID:11377794]
subset: gosubset_prok
is_a: GO:0000375

[Term]
id: GO:0000377
name: RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
namespace: biological_process
def: "Splicing of RNA via a series of two transesterification reactions with a bulged adenosine residue from the intron branch point as the initiating nucleophile. When the initial RNA for the splicing reaction is a single molecule (cis splicing), the excised intron is released in a lariat structure." [GOC:krc, PMID:11377794]
subset: gosubset_prok
is_a: GO:0000375
synonym: "lariat RNA biosynthesis" RELATED []
synonym: "lariat RNA formation" RELATED []

[Term]
id: GO:0000378
name: RNA exon ligation
namespace: biological_process
def: "The process of joining two exons, each of which has free ends that were generated by endonucleolytic cleavages, by a ligation reaction." [GOC:krc, ISBN:0879695897]
comment: Note that this is not a part of spliceosomal RNA splicing.
subset: gosubset_prok
is_a: GO:0016070
relationship: OBO_REL:part_of GO:0000394

[Term]
id: GO:0000379
name: tRNA-type intron splice site recognition and cleavage
namespace: biological_process
def: "The process of recognition of the tertiary structure of a tRNA type intron and the endonucleolytic cleavage of the RNA at both the 5' and 3' splice sites." [GOC:krc, ISBN:0879695897]
subset: gosubset_prok
is_a: GO:0006396
relationship: OBO_REL:part_of GO:0000394

[Term]
id: GO:0000380
name: alternative nuclear mRNA splicing, via spliceosome
namespace: biological_process
def: "The process of generating multiple mRNA molecules from a given set of exons by differential use of exons from the primary transcript(s) to form multiple mature mRNAs that vary in their exon composition." [GOC:krc, PMID:12110900]
comment: Note that this process most commonly occurs in cis, selecting or skipping exons from the same primary transcript, but it has also been observed to occur in trans at low frequency, at least in some mammals.
is_a: GO:0000398
synonym: "splice site selection" BROAD []

[Term]
id: GO:0000381
name: regulation of alternative nuclear mRNA splicing, via spliceosome
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs." [GOC:krc]
is_a: GO:0048024
relationship: regulates GO:0000380
synonym: "splice site selection" BROAD []

[Term]
id: GO:0000387
name: spliceosomal snRNP biogenesis
namespace: biological_process
def: "The formation and assembly from one or more snRNA and multiple protein components of a ribonucleoprotein complex that in involved in formation of the spliceosome." [GOC:krc, ISBN:0879695897]
is_a: GO:0022613
relationship: OBO_REL:part_of GO:0000398

[Term]
id: GO:0000388
name: spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
alt_id: GO:0000396
alt_id: GO:0000397
namespace: biological_process
def: "Rearrangement of the pre-catalytic spliceosome containing U4 (or U4atac) and U1 (or U11) snRNPs to unpair U4 (or U4atac) from U6 (or U6atac) and release it from the spliceosomal complex along with U1 (or U11)." [GOC:krc, ISBN:0879695897]
comment: Note that this step represents formation of the A1 complex (yeast) or the B2 complex (mammalian).
is_a: GO:0022618
relationship: OBO_REL:part_of GO:0000393
synonym: "3'-splice site cleavage, exon ligation" BROAD []
synonym: "spliceosomal A1 complex biosynthesis" NARROW []
synonym: "spliceosomal A1 complex formation" NARROW []
synonym: "spliceosomal B2 complex biosynthesis" NARROW []
synonym: "spliceosomal B2 complex formation" NARROW []
synonym: "U12-type spliceosome conformational change to release U4atac and U11" NARROW []
synonym: "U2-type spliceosome conformational change to release U4 and U1" NARROW []

[Term]
id: GO:0000389
name: nuclear mRNA 3'-splice site recognition
alt_id: GO:0000382
alt_id: GO:0000383
namespace: biological_process
def: "Recognition of the intron 3'-splice site by components of the assembling U2- or U12-type spliceosome." [GOC:krc, ISBN:0879695897]
is_a: GO:0006376
synonym: "U12-type nuclear mRNA 3'-splice site recognition" NARROW []
synonym: "U2-type nuclear mRNA 3'-splice site recognition" NARROW []

[Term]
id: GO:0000390
name: spliceosome disassembly
alt_id: GO:0000391
alt_id: GO:0000392
namespace: biological_process
def: "Disassembly of the spliceosome with the ATP-dependent release of the product RNAs, one of which is composed of the joined exons. In cis splicing, the other product is the excised sequence, often a single intron, in a lariat structure." [GOC:krc, ISBN:0879695897]
is_a: GO:0032988
relationship: OBO_REL:part_of GO:0000398
synonym: "spliceosome complex disassembly" EXACT []
synonym: "U12-type spliceosome disassembly" NARROW []
synonym: "U2-type spliceosome disassembly" NARROW []

[Term]
id: GO:0000393
name: spliceosomal conformational changes to generate catalytic conformation
namespace: biological_process
def: "Structural rearrangements of the spliceosome complex, containing RNA to be spliced, to generate a catalytic conformation." [GOC:krc]
is_a: GO:0022618
relationship: OBO_REL:part_of GO:0000398
synonym: "3'-splice site cleavage, exon ligation" BROAD []

[Term]
id: GO:0000394
name: RNA splicing, via endonucleolytic cleavage and ligation
namespace: biological_process
def: "Splicing of RNA via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons." [GOC:krc, ISBN:0879695897]
comment: Note that while typically associated with tRNA splicing, this mechanism of splicing is known to be used for some non-tRNA substrates, e.g. HAC1 (YFL031W) in S. cerevisiae and an intron in the 23S rRNA of the Archaeal species Desulfurococcus mobilis.
subset: gosubset_prok
is_a: GO:0008380
synonym: "mRNA splicing" BROAD []

[Term]
id: GO:0000395
name: nuclear mRNA 5'-splice site recognition
alt_id: GO:0000368
alt_id: GO:0000369
namespace: biological_process
def: "Recognition of the intron 5'-splice site by components of the assembling spliceosome." [GOC:krc, ISBN:0879695897]
comment: Note that this step represents formation of the Commitment Complex (CC, in yeast) or the E complex (mammalian).
is_a: GO:0006376
relationship: OBO_REL:part_of GO:0045292
synonym: "nuclear mRNA 5' splice site recognition" EXACT []
synonym: "spliceosomal CC complex biosynthesis" NARROW []
synonym: "spliceosomal CC complex formation" NARROW []
synonym: "spliceosomal commitment complex biosynthesis" NARROW []
synonym: "spliceosomal commitment complex formation" NARROW []
synonym: "spliceosomal E complex biosynthesis" NARROW []
synonym: "spliceosomal E complex formation" NARROW []
synonym: "U12-type nuclear mRNA 5' splice site recognition" NARROW []
synonym: "U12-type nuclear mRNA 5'-splice site recognition" NARROW []
synonym: "U2-type nuclear mRNA 5' splice site recognition" NARROW []
synonym: "U2-type nuclear mRNA 5'-splice site recognition" NARROW []

[Term]
id: GO:0000398
name: nuclear mRNA splicing, via spliceosome
alt_id: GO:0006374
alt_id: GO:0006375
namespace: biological_process
def: "The joining together of exons from one or more primary transcripts of nuclear messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced." [GOC:krc, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", ISBN:0879695897]
comment: Note that although the many U12-type introns have the sequence AT-AC at the intron termini, some introns with these terminal sequences are spliced by the U2-type spliceosome. The distinguishing characteristics are sequences near the 5' splice site and the branch point sequences of the intron. Note that although the majority of U2-type introns have the sequence GU-AG at the intron termini, some introns with these terminal sequences are spliced by the U12-type spliceosome. The distinguishing characteristics are sequences near the 5' splice site and the branch point sequences of the intron.
is_a: GO:0000377
is_a: GO:0006397
synonym: "mRNA splicing" BROAD []
synonym: "nuclear mRNA splicing via U12-type spliceosome" NARROW []
synonym: "nuclear mRNA splicing via U2-type spliceosome" NARROW []
synonym: "pre-mRNA splicing" BROAD []
synonym: "splicing AT-AC intron" RELATED []
synonym: "splicing GT-AG intron" RELATED []
xref: Reactome:212002
xref: Reactome:221766
xref: Reactome:238383
xref: Reactome:244938
xref: Reactome:249819
xref: Reactome:255735
xref: Reactome:259129
xref: Reactome:262486
xref: Reactome:274165
xref: Reactome:280638
xref: Reactome:286656
xref: Reactome:288338
xref: Reactome:291782
xref: Reactome:293761
xref: Reactome:72172

[Term]
id: GO:0000409
name: regulation of transcription by galactose
namespace: biological_process
def: "Any process involving galactose that modulates the frequency, rate or extent or transcription." [GOC:go_curators]
subset: gosubset_prok
is_a: GO:0045990

[Term]
id: GO:0000410
name: negative regulation of transcription by galactose
namespace: biological_process
def: "Any process involving galactose that stops, prevents or reduces the rate of transcription." [GOC:mah]
is_a: GO:0000409
is_a: GO:0045013
synonym: "down regulation of transcription by galactose" EXACT []
synonym: "down-regulation of transcription by galactose" EXACT []
synonym: "downregulation of transcription by galactose" EXACT []
synonym: "inhibition of transcription by galactose" NARROW []

[Term]
id: GO:0000411
name: positive regulation of transcription by galactose
namespace: biological_process
def: "Any process involving galactose that activates or increases the rate of transcription." [GOC:go_curators]
is_a: GO:0000409
is_a: GO:0045991
synonym: "activation of transcription by galactose" NARROW []
synonym: "stimulation of transcription by galactose" NARROW []
synonym: "up regulation of transcription by galactose" EXACT []
synonym: "up-regulation of transcription by galactose" EXACT []
synonym: "upregulation of transcription by galactose" EXACT []

[Term]
id: GO:0000412
name: histone peptidyl-prolyl isomerization
namespace: biological_process
def: "The modification of a histone by cis-trans isomerization of a proline residue." [GOC:krc]
is_a: GO:0000413
is_a: GO:0016570
synonym: "histone proline isomerization" EXACT []

[Term]
id: GO:0000413
name: protein peptidyl-prolyl isomerization
namespace: biological_process
def: "The modification of a protein by cis-trans isomerization of a proline residue." [GOC:krc, PMID:16959570]
is_a: GO:0043687
synonym: "protein proline isomerization" EXACT []

[Term]
id: GO:0000414
name: regulation of histone H3-K36 methylation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 36 of histone H3." [GOC:krc]
is_a: GO:0031060
relationship: regulates GO:0010452

[Term]
id: GO:0000415
name: negative regulation of histone H3-K36 methylation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 36 of histone H3." [GOC:krc]
is_a: GO:0000414
is_a: GO:0031061
relationship: negatively_regulates GO:0010452
synonym: "down regulation of histone H3-K36 methylation" EXACT []
synonym: "down-regulation of histone H3-K36 methylation" EXACT []
synonym: "downregulation of histone H3-K36 methylation" EXACT []
synonym: "inhibition of histone H3-K36 methylation" NARROW []

[Term]
id: GO:0000416
name: positive regulation of histone H3-K36 methylation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 36 of histone H3." [GOC:krc]
is_a: GO:0000414
is_a: GO:0031062
relationship: positively_regulates GO:0010452
synonym: "activation of histone H3-K36 methylation" NARROW []
synonym: "stimulation of histone H3-K36 methylation" NARROW []
synonym: "up regulation of histone H3-K36 methylation" EXACT []
synonym: "up-regulation of histone H3-K36 methylation" EXACT []
synonym: "upregulation of histone H3-K36 methylation" EXACT []

[Term]
id: GO:0000422
name: mitochondrion degradation
namespace: biological_process
def: "The process by which mitochondria are delivered to the vacuole and degraded in response to changing cellular conditions, autophagy of mitochondria." [PMID:15798367]
is_a: GO:0006914
synonym: "mitophagy" EXACT []

[Term]
id: GO:0000423
name: macromitophagy
namespace: biological_process
def: "Degradation of a mitochondrion by macroautophagy." [PMID:15798367]
is_a: GO:0000422
is_a: GO:0016236

[Term]
id: GO:0000424
name: micromitophagy
namespace: biological_process
def: "Degradation of a mitochondrion by microautophagy." [PMID:15798367]
is_a: GO:0000422
is_a: GO:0016237

[Term]
id: GO:0000425
name: macropexophagy
namespace: biological_process
def: "Degradation of a peroxisome by macropexophagy." [PMID:12914914, PMID:16973210]
is_a: GO:0016236
is_a: GO:0030242

[Term]
id: GO:0000426
name: micropexophagy
namespace: biological_process
def: "Degradation of a peroxisome by micropexophagy." [PMID:12914914, PMID:16973210]
is_a: GO:0016237
is_a: GO:0030242

[Term]
id: GO:0000429
name: regulation of transcription from RNA polymerase II promoter by carbon catabolites
namespace: biological_process
def: "Any process involving carbon catabolites that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:krc]
is_a: GO:0006357
is_a: GO:0045990

[Term]
id: GO:0000430
name: regulation of transcription from RNA polymerase II promoter by glucose
namespace: biological_process
def: "Any process involving glucose that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:krc]
is_a: GO:0000429
is_a: GO:0046015

[Term]
id: GO:0000431
name: regulation of transcription from RNA polymerase II promoter by galactose
namespace: biological_process
def: "Any process involving galactose that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:krc]
is_a: GO:0000409
is_a: GO:0000429

[Term]
id: GO:0000432
name: positive regulation of transcription from RNA polymerase II promoter by glucose
namespace: biological_process
def: "Any process involving glucose that activates or increases the rate of transcription from an RNA polymerase II promoter." [GOC:krc]
is_a: GO:0000430
is_a: GO:0000436
is_a: GO:0046016
synonym: "activation of transcription from RNA polymerase II promoter by glucose" NARROW []
synonym: "stimulation of transcription from RNA polymerase II promoter by glucose" NARROW []
synonym: "up regulation of transcription from RNA polymerase II promoter by glucose" EXACT []
synonym: "up-regulation of transcription from RNA polymerase II promoter by glucose" EXACT []
synonym: "upregulation of transcription from RNA polymerase II promoter by glucose" EXACT []

[Term]
id: GO:0000433
name: negative regulation of transcription from RNA polymerase II promoter by glucose
namespace: biological_process
def: "Any process involving glucose that stops, prevents or reduces the rate of transcription from an RNA polymerase II promoter." [GOC:krc]
is_a: GO:0000430
is_a: GO:0000437
is_a: GO:0045014
synonym: "down regulation of transcription from RNA polymerase II promoter by glucose" EXACT []
synonym: "down-regulation of transcription from RNA polymerase II promoter by glucose" EXACT []
synonym: "downregulation of transcription from RNA polymerase II promoter by glucose" EXACT []
synonym: "inhibition of transcription from RNA polymerase II promoter by glucose" NARROW []

[Term]
id: GO:0000434
name: negative regulation of transcription from RNA polymerase II promoter by galactose
namespace: biological_process
def: "Any process involving galactose that stops, prevents or reduces the rate of transcription from an RNA polymerase II promoter." [GOC:krc]
is_a: GO:0000410
is_a: GO:0000431
is_a: GO:0000437
synonym: "down regulation of transcription from RNA polymerase II promoter by galactose" EXACT []
synonym: "down-regulation of transcription from RNA polymerase II promoter by galactose" EXACT []
synonym: "downregulation of transcription from RNA polymerase II promoter by galactose" EXACT []
synonym: "inhibition of transcription from RNA polymerase II promoter by galactose" NARROW []

[Term]
id: GO:0000435
name: positive regulation of transcription from RNA polymerase II promoter by galactose
namespace: biological_process
def: "Any process involving galactose that activates or increases the rate of transcription from an RNA polymerase II promoter." [GOC:krc]
is_a: GO:0000411
is_a: GO:0000431
is_a: GO:0000436
synonym: "activation of transcription from RNA polymerase II promoter by galactose" NARROW []
synonym: "stimulation of transcription from RNA polymerase II promoter by galactose" NARROW []
synonym: "up regulation of transcription from RNA polymerase II promoter by galactose" EXACT []
synonym: "up-regulation of transcription from RNA polymerase II promoter by galactose" EXACT []
synonym: "upregulation of transcription from RNA polymerase II promoter by galactose" EXACT []

[Term]
id: GO:0000436
name: positive regulation of transcription from RNA polymerase II promoter by carbon catabolites
namespace: biological_process
def: "Any process involving carbon catabolites that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:krc]
is_a: GO:0000429
is_a: GO:0045944
synonym: "activation of transcription from RNA polymerase II promoter by carbon catabolites" NARROW []
synonym: "stimulation of transcription from RNA polymerase II promoter by carbon catabolites" NARROW []
synonym: "up regulation of transcription from RNA polymerase II promoter by carbon catabolites" EXACT []
synonym: "up-regulation of transcription from RNA polymerase II promoter by carbon catabolites" EXACT []
synonym: "upregulation of transcription from RNA polymerase II promoter by carbon catabolites" EXACT []

[Term]
id: GO:0000437
name: negative regulation of transcription from RNA polymerase II promoter by carbon catabolites
namespace: biological_process
def: "Any process involving carbon catabolites that stops, prevents or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:krc]
is_a: GO:0000122
is_a: GO:0000429
synonym: "down regulation of transcription from RNA polymerase II promoter by carbon catabolites" EXACT []
synonym: "down-regulation of transcription from RNA polymerase II promoter by carbon catabolites" EXACT []
synonym: "downregulation of transcription from RNA polymerase II promoter by carbon catabolites" EXACT []
synonym: "inhibition of transcription from RNA polymerase II promoter by carbon catabolites" NARROW []

[Term]
id: GO:0000447
name: endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
namespace: biological_process
def: "Endonucleolytic cleavage beween the SSU-rRNA and the 5.8S rRNA of an rRNA molecule originally produced as a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript." [GOC:curators, PMID:10690410]
is_a: GO:0000479
relationship: OBO_REL:part_of GO:0000462
relationship: OBO_REL:part_of GO:0000466
synonym: "endonucleolytic cleavage at A2" NARROW []

[Term]
id: GO:0000448
name: cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
alt_id: GO:0000490
namespace: biological_process
def: "Endonucleolytic cleavage within ITS2 between the 5.8S rRNA and the LSU-rRNA of an rRNA molecule originally produced as a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript." [GOC:curators, PMID:10690410]
is_a: GO:0000479
relationship: OBO_REL:part_of GO:0000463
relationship: OBO_REL:part_of GO:0000466
synonym: "cleavage at C2" RELATED []
synonym: "cleavage in ITS2 of tricistronic rRNA transcript to separate 5.8S and LSU rRNAs (SSU-rRNA, 5.8S rRNA, LSU-rRNA)" EXACT []

[Term]
id: GO:0000449
name: endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 5S)
namespace: biological_process
def: "Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the Large Subunit (LSU) rRNA, and the 5S rRNA, in that order, from 5' to 3' along the primary transcript. For example, primary ribosomal RNA transcripts containing three genes, in this order, are produced in E. coli and other prokaryotic species. Note that the use of the word tricistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript." [GOC:curators]
is_a: GO:0000478

[Term]
id: GO:0000450
name: cleavage of bicistronic rRNA transcript (SSU-rRNA, LSU-rRNA)
namespace: biological_process
def: "Endonucleolytic cleavage of pre-rRNAs originally produced as a bicistronic rRNA transcript that contains the SSU-rRNA and the LSU-rRNA in that order from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with two genes in this order are produced in Archaeal species." [GOC:curators]
is_a: GO:0000478

[Term]
id: GO:0000451
name: rRNA 2'-O-methylation
namespace: biological_process
def: "The addition of a methyl group to the 2'-oxygen atom of a nucleotide residue in an rRNA molecule during ribosome biogenesis." [GOC:curators, ISBN:1555811337 "Modification and Editing of RNA"]
is_a: GO:0031167

[Term]
id: GO:0000452
name: snoRNA guided rRNA 2'-O-methylation
namespace: biological_process
def: "The posttranscriptional addition of methyl groups to the 2'-oxygen atom of nucleotide residues in an rRNA molecule during ribosome biogenesis using a snoRNA guide that targets the position of methylation." [GOC:curators, ISBN:1555811337 "Modification and Editing of RNA"]
is_a: GO:0000451

[Term]
id: GO:0000453
name: enzyme-directed rRNA 2'-O-methylation
namespace: biological_process
def: "The addition of methyl groups to the 2'-oxygen atom of nucleotide residues in an rRNA molecule during ribosome biogenesis where the methylase specifies the site that becomes methylated without using a guide RNA." [GOC:curators, ISBN:1555811337 "Modification and Editing of RNA"]
is_a: GO:0000451

[Term]
id: GO:0000454
name: snoRNA guided rRNA pseudouridine synthesis
namespace: biological_process
def: "The intramolecular conversion of uridine to pseudouridine in an rRNA molecule during ribosome biogenesis using a snoRNA guide that targets the position of pseudouridylation." [GOC:curators, ISBN:1555811337 "Modification and Editing of RNA"]
is_a: GO:0031118

[Term]
id: GO:0000455
name: enzyme-directed rRNA pseudouridine synthesis
namespace: biological_process
def: "The intramolecular conversion of uridine to pseudouridine during ribosome biogenesis where the enzyme specifies the site that becomes pseudouridylated without using a guide RNA." [GOC:curators, ISBN:1555811337 "Modification and Editing of RNA"]
is_a: GO:0031118

[Term]
id: GO:0000456
name: dimethylation during SSU-rRNA biogenesis
namespace: biological_process
def: "Dimethyation of the N6 amino groups of two consecutive adenosine residues near the 3'-end of the SSU rRNA. This process has been conserved from bacteria to eukaryotes." [GOC:curators, ISBN:1555811337 "Modification and Editing of RNA"]
is_a: GO:0031167

[Term]
id: GO:0000457
name: endonucleolytic cleavage between SSU-rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 5S)
namespace: biological_process
def: "Endonucleolytic cleavage to separate a pre-SSU-rRNA from a pre-LSU-rRNA originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the Large Subunit (LSU) rRNA, and the 5S rRNA, in that order, from 5' to 3' along the primary transcript. Note that the use of the word tricistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript." [GOC:curators]
is_a: GO:0000449
relationship: OBO_REL:part_of GO:0002108
relationship: OBO_REL:part_of GO:0002109

[Term]
id: GO:0000458
name: endonucleolytic cleavage between LSU-rRNA and 5S rRNA of tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 5S)
namespace: biological_process
def: "Endonucleolytic cleavage to separate a pre-LSU-rRNA from a pre-5S rRNA originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the Large Subunit (LSU) rRNA, and the 5S rRNA, in that order, from 5' to 3' along the primary transcript. Note that the use of the word tricistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript." [GOC:curators]
is_a: GO:0000449
relationship: OBO_REL:part_of GO:0002108

[Term]
id: GO:0000459
name: exonucleolytic trimming during rRNA processing
namespace: biological_process
def: "Exonucleolytic digestion of a pre-rRNA molecule in the process to generate a mature rRNA molecule." [GOC:curators]
is_a: GO:0000469

[Term]
id: GO:0000460
name: maturation of 5.8S rRNA
namespace: biological_process
def: "Any process involved in the maturation of a precursor 5.8S ribosomal RNA (rRNA) molecule into a mature 5.8S rRNA molecule." [GOC:curators]
is_a: GO:0006364

[Term]
id: GO:0000461
name: endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
namespace: biological_process
def: "Endonucleolytic cleavage at the 3'-end of the SSU-rRNA from an originally tricistronic rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript, to produce the mature end of the SSU-rRNA." [GOC:krc, PMID:10690410]
is_a: GO:0000479
is_a: GO:0031125
relationship: OBO_REL:part_of GO:0000462
synonym: "endonucleolytic cleavage at site D" NARROW []

[Term]
id: GO:0000462
name: maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
namespace: biological_process
def: "Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and the Large Subunit (LSU) in that order from 5' to 3' along the primary transcript." [GOC:curators]
is_a: GO:0030490

[Term]
id: GO:0000463
name: maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
namespace: biological_process
def: "Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript." [GOC:curators]
is_a: GO:0000470

[Term]
id: GO:0000464
name: endonucleolytic cleavage in ITS1 upstream of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
namespace: biological_process
def: "Endonucleolytic cleavage within Internal Transcribed Spacer 1 (ITS1) upstream of the 5.8S rRNA derived from an originally tricistronic rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript. In S. cerevisiae, this endonucleolytic cleavage within ITS1 initiates the maturation of the LSU and the 5.8S rRNAs." [GOC:krc, PMID:10690410]
is_a: GO:0000479
relationship: OBO_REL:part_of GO:0000463
relationship: OBO_REL:part_of GO:0000466
synonym: "endonucleolytic cleavage at A3" NARROW []

[Term]
id: GO:0000465
name: exonucleolytic trimming to generate mature 5'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
namespace: biological_process
def: "Exonucleolytic digestion of a pre-rRNA molecule to generate the mature 5'-end of a 5.8S rRNA molecule derived from an originally tricistronic pre-rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript." [GOC:krc, PMID:10690410]
is_a: GO:0000459
is_a: GO:0000967
relationship: OBO_REL:part_of GO:0000466

[Term]
id: GO:0000466
name: maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
namespace: biological_process
def: "Any process involved in the maturation of an rRNA molecule originally produced as part of a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript." [GOC:curators, PMID:10690410]
is_a: GO:0000460

[Term]
id: GO:0000467
name: exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
namespace: biological_process
def: "Exonucleolytic digestion of a pre-rRNA molecule to generate the mature 3'-end of a 5.8S rRNA molecule derived from an originally tricistronic pre-rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript." [GOC:krc, PMID:10690410]
is_a: GO:0000459
is_a: GO:0031125
relationship: OBO_REL:part_of GO:0000466

[Term]
id: GO:0000468
name: generation of mature 3'-end of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
namespace: biological_process
def: "Any process involved in generating the mature 3'-end of an LSU-rRNA derived from a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript." [GOC:krc, PMID:10690410]
is_a: GO:0031125
relationship: OBO_REL:part_of GO:0000463
synonym: "processing at B2" NARROW []

[Term]
id: GO:0000469
name: cleavages during rRNA processing
namespace: biological_process
def: "Any cleavage involved in the conversion of a primary ribosomal RNA (rRNA) transcript into a mature rRNA molecule." [GOC:curators]
is_a: GO:0006364

[Term]
id: GO:0000470
name: maturation of LSU-rRNA
namespace: biological_process
def: "Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule." [GOC:curators]
is_a: GO:0006364

[Term]
id: GO:0000471
name: endonucleolytic cleavage in 3'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
namespace: biological_process
def: "Endonucleolytic cleavage within the 3'-External Transcribed Spacer (ETS) of a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript. In S. cerevisiae, endonucleolytic cleavage within the 3'-ETS of the pre-RNA, which may occur cotranscriptionally, is the first step in rRNA processing, and initiates a cascade of subsequent processing and modification events." [GOC:krc, PMID:10690410]
is_a: GO:0000479

[Term]
id: GO:0000472
name: endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
namespace: biological_process
def: "Endonucleolytic cleavage between the 5'-External Transcribed Spacer (5'-ETS) and the 5' end of the SSU-rRNA of a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript, to produce the mature end of the SSU-rRNA." [GOC:curators, PMID:10690410]
is_a: GO:0000479
is_a: GO:0000967
relationship: OBO_REL:part_of GO:0000462
synonym: "endonucleolytic cleavage at A1" NARROW []

[Term]
id: GO:0000473
name: maturation of LSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)
namespace: biological_process
def: "Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8 S rRNA, 2S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript." [GOC:curators]
is_a: GO:0000470

[Term]
id: GO:0000474
name: maturation of SSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)
namespace: biological_process
def: "Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8 S rRNA, 2S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript." [GOC:curators]
is_a: GO:0030490

[Term]
id: GO:0000475
name: maturation of 2S rRNA
namespace: biological_process
def: "Any process involved in the maturation of a precursor 2S ribosomal RNA (rRNA) molecule into a mature 2S rRNA molecule." [GOC:curators]
is_a: GO:0006364

[Term]
id: GO:0000476
name: maturation of 4.5S rRNA
namespace: biological_process
def: "Any process involved in the maturation of a precursor 4.5S ribosomal RNA (rRNA) molecule into a mature 4.5S rRNA molecule." [GOC:curators]
is_a: GO:0006364

[Term]
id: GO:0000477
name: generation of mature 5'-end of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
namespace: biological_process
def: "Cleavage within ITS2 to generate the mature 5'-end of an LSU-rRNA derived from a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript." [GOC:curators, PMID:10690410]
is_a: GO:0000469
is_a: GO:0000967
relationship: OBO_REL:part_of GO:0000463
synonym: "processing at C1" NARROW []

[Term]
id: GO:0000478
name: endonucleolytic cleavages during rRNA processing
namespace: biological_process
def: "Any endonucleolytic cleavage involved in the conversion of a primary ribosomal RNA (rRNA) transcript into a mature rRNA molecule. Some endonucleolytic cleavages produce the mature end, while others are a step in the process of generating the mature end from the pre-rRNA." [PMID:10690410, SGD:krc]
is_a: GO:0000469

[Term]
id: GO:0000479
name: endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
namespace: biological_process
def: "Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with three genes, in this order, are produced in the nuclei of many eukaryotic species, including S. cerevisiae." [GOC:curators, PMID:10690410]
is_a: GO:0000478

[Term]
id: GO:0000480
name: endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
namespace: biological_process
def: "Endonucleolytic cleavage within the 5'-External Transcribed Spacer (ETS) of a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript. Endonucleolytic cleavage within the 5'-ETS of the pre-RNA is conserved as one of the early steps of rRNA processing in all eukaryotes, but the specific position of cleavage is variable." [GOC:curators, PMID:10690410, PMID:15282326]
is_a: GO:0000479
relationship: OBO_REL:part_of GO:0000462
synonym: "endonucleolytic cleavage at A-prime" NARROW [PMID:15282326]
synonym: "endonucleolytic cleavage at A0" NARROW []

[Term]
id: GO:0000481
name: maturation of 5S rRNA
namespace: biological_process
def: "Any process involved in the maturation of a precursor 5S ribosomal RNA (rRNA) molecule into a mature 5S rRNA molecule." [GOC:curators]
is_a: GO:0006364

[Term]
id: GO:0000482
name: maturation of 5S rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
namespace: biological_process
def: "Any process involved in the maturation of a precursor 5S ribosomal RNA (rRNA) molecule into a mature 5S rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript." [GOC:curators]
is_a: GO:0000481

[Term]
id: GO:0000483
name: endonucleolytic cleavage of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)
namespace: biological_process
def: "Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small SubUnit (SSU) rRNA, the 5.8S rRNA, 2S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with four genes, in this order, are produced in the nuclei of D. melanogaster as well as in those of other dipteran species." [GOC:curators]
is_a: GO:0000478

[Term]
id: GO:0000484
name: cleavage between SSU-rRNA and 5.8S rRNA of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)
namespace: biological_process
def: "Endonucleolytic cleavage beween the SSU-rRNA and the 5.8S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, 2S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript." [GOC:curators]
is_a: GO:0000483
relationship: OBO_REL:part_of GO:0000474
relationship: OBO_REL:part_of GO:0000487

[Term]
id: GO:0000485
name: cleavage between 2S rRNA and LSU-rRNA of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)
namespace: biological_process
def: "Endonucleolytic cleavage beween the LSU-rRNA and the 2S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, 2S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript." [GOC:curators, PMID:768488]
is_a: GO:0000483
relationship: OBO_REL:part_of GO:0000473
relationship: OBO_REL:part_of GO:0000475

[Term]
id: GO:0000486
name: cleavage between 5.8S rRNA and 2S rRNA of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)
namespace: biological_process
def: "Endonucleolytic cleavage beween the 5.8S rRNA and the 2S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, 2S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript." [GOC:curators, PMID:768488]
is_a: GO:0000483
relationship: OBO_REL:part_of GO:0000475
relationship: OBO_REL:part_of GO:0000487

[Term]
id: GO:0000487
name: maturation of 5.8S rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)
namespace: biological_process
def: "Any process involved in the maturation of a precursor 5.8S ribosomal RNA (rRNA) molecule into a mature 5.8S rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 8.8S rRNA, the 2S rRNA, and the Large Subunit (LSU) in that order from 5' to 3' along the primary transcript." [GOC:curators]
is_a: GO:0000460

[Term]
id: GO:0000488
name: maturation of LSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)
namespace: biological_process
def: "Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript." [GOC:curators]
is_a: GO:0000470

[Term]
id: GO:0000489
name: maturation of SSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)
namespace: biological_process
def: "Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript." [GOC:curators]
is_a: GO:0030490

[Term]
id: GO:0000491
name: snoRNP assembly
namespace: biological_process
def: "The aggregation, arrangement and bonding together of proteins and a snoRNA to form a small nucleolar ribonucleoprotein (snoRNP) complex." [GO:krc]
is_a: GO:0022618
synonym: "small nucleolar ribonucleoprotein complex assembly" EXACT []

[Term]
id: GO:0000492
name: box C/D snoRNP assembly
namespace: biological_process
def: "The aggregation, arrangement and bonding together of proteins and a box C/D snoRNA to form a box C/D small nucleolar ribonucleoprotein (snoRNP) complex." [GO:krc]
is_a: GO:0000491
synonym: "box C/D small nucleolar ribonucleoprotein complex assembly" EXACT []

[Term]
id: GO:0000493
name: box H/ACA snoRNP assembly
namespace: biological_process
def: "The aggregation, arrangement and bonding together of proteins and a box H/ACA snoRNA to form a box H/ACA small nucleolar ribonucleoprotein (snoRNP) complex." [GO:krc, PMID:12515383]
is_a: GO:0000491
synonym: "box H/ACA small nucleolar ribonucleoprotein complex assembly" EXACT []

[Term]
id: GO:0000494
name: box C/D snoRNA 3'-end processing
namespace: biological_process
def: "Any process involved in forming the mature 3' end of a box C/D snoRNA molecule." [GO:krc]
is_a: GO:0031126
is_a: GO:0033967
synonym: "box C/D snoRNA 3' end processing" EXACT []

[Term]
id: GO:0000495
name: box H/ACA snoRNA 3'-end processing
namespace: biological_process
def: "Any process involved in forming the mature 3' end of a box H/ACA snoRNA molecule." [GO:krc]
is_a: GO:0031126
is_a: GO:0033979
synonym: "box H/ACA snoRNA 3' end processing" EXACT []

[Term]
id: GO:0000501
name: flocculation via cell wall protein-carbohydrate interaction
namespace: biological_process
def: "Mannose-sensitive, nonsexual aggregation of cells mediated by protein-carbohydrate (flocculin-mannan) interaction present in the cell wall. This process is pH- and calcium-dependent and reversible." [DOI:10.1016/S0963-9969(99)00021-6, GOC:sgd_curators]
subset: gosubset_prok
is_a: GO:0000128
synonym: "flocculation (sensu Saccharomyces)" NARROW []

[Term]
id: GO:0000578
name: embryonic axis specification
namespace: biological_process
def: "Axis specification in the embryo." [GOC:go_curators]
is_a: GO:0009798
is_a: GO:0009880
synonym: "embryonic axis determination" EXACT []

[Term]
id: GO:0000705
name: achiasmate meiosis I
namespace: biological_process
def: "The first division of meiosis in which homologous chromosomes are paired and segregated from each other, occurring in the constitutive absence of chiasmata." [GOC:elh, GOC:sart, PMID:10690419]
is_a: GO:0007127

[Term]
id: GO:0000706
name: meiotic DNA double-strand break processing
namespace: biological_process
def: "The cell cycle process whereby the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang occurs. This takes place during meiosis." [GOC:elh, PMID:9334324]
is_a: GO:0000729
is_a: GO:0022402
relationship: OBO_REL:part_of GO:0006311
relationship: OBO_REL:part_of GO:0007131

[Term]
id: GO:0000707
name: meiotic DNA recombinase assembly
namespace: biological_process
def: "During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form higher order oligomers on single-stranded DNA." [GOC:elh, PMID:11459983]
is_a: GO:0000730
is_a: GO:0022402
relationship: OBO_REL:part_of GO:0006311
relationship: OBO_REL:part_of GO:0007131

[Term]
id: GO:0000708
name: meiotic strand invasion
namespace: biological_process
def: "The cell cycle process whereby the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules. This occurs during meiosis." [GOC:elh, PMID:10915877]
is_a: GO:0022402
is_a: GO:0042148
relationship: OBO_REL:part_of GO:0006311
relationship: OBO_REL:part_of GO:0007131
synonym: "meiotic D-loop biosynthesis" RELATED []
synonym: "meiotic D-loop formation" RELATED []

[Term]
id: GO:0000709
name: meiotic joint molecule formation
namespace: biological_process
def: "The conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule, formed during meiotic recombination. These joint molecules contain Holliday junctions on either side of heteroduplex DNA." [GOC:elh, PMID:8521495]
is_a: GO:0022402
relationship: OBO_REL:part_of GO:0007131

[Term]
id: GO:0000710
name: meiotic mismatch repair
namespace: biological_process
def: "A system for the identification and correction of base-base mismatches, small insertion-deletion loops, and regions of heterology that are present in duplex DNA formed with strands from two recombining molecules. Correction of the mismatch can result in non-Mendelian segregation of alleles following meiosis." [GOC:elh, PMID:10357855]
is_a: GO:0006298
is_a: GO:0022402
relationship: OBO_REL:part_of GO:0006311
relationship: OBO_REL:part_of GO:0007131

[Term]
id: GO:0000711
name: meiotic DNA repair synthesis
namespace: biological_process
def: "During meiosis, the synthesis of DNA proceeding from the broken 3' single-strand DNA end that uses the homologous intact duplex as the template." [GOC:elh, PMID:9334324]
is_a: GO:0000731
is_a: GO:0022402
relationship: OBO_REL:part_of GO:0006311
relationship: OBO_REL:part_of GO:0007131

[Term]
id: GO:0000712
name: resolution of meiotic joint molecules as recombinants
namespace: biological_process
def: "The cleavage and rejoining of Holliday junctions fo