| ID | NIF_Dysfunction:birnlex_12577 |
|---|---|
| ID Space | NIF_Dysfunction |
| Name | Striatonigral Degeneration |
| Ontology | birnlex_anatomy |
| Definition | A sporadic neurodegenerative disease with onset in middle-age characterized clinically by Parkinsonian features (e.g., MUSCLE RIGIDITY; HYPOKINESIA; stooped posture) and HYPOTENSION. This condition is considered a clinical variant of MULTIPLE SYSTEM ATROPHY. Pathologic features include a prominent loss of neurons in the zona compacta of the SUBSTANTIA NIGRA and PUTAMEN (MeSH). http://ontology.neuinfo.org/NIF/Backend/OBO_annotation_properties.owl#MeSH_defSource |
| http://www.w3.org/2004/02/skos/core#definition | A sporadic neurodegenerative disease with onset in middle-age characterized clinically by Parkinsonian features (e.g., MUSCLE RIGIDITY; HYPOKINESIA; stooped posture) and HYPOTENSION. This condition is considered a clinical variant of MULTIPLE SYSTEM ATROPHY. Pathologic features include a prominent loss of neurons in the zona compacta of the SUBSTANTIA NIGRA and PUTAMEN (MeSH). |
| http://www.w3.org/2004/02/skos/core#prefLabel | Striatonigral Degeneration |
| nif_annot:hasBirnlexCurator | http://ontology.neuinfo.org/NIF/Backend/BIRNLex_annotation_properties.owl#BillBug |
| nif_annot:hasCurationStatus | http://ontology.neuinfo.org/NIF/Backend/BIRNLex_annotation_properties.owl#uncurated |
| nif_obo_annot:MeshUid | D020955 |
| nif_obo_annot:createdDate | 2007-10-05 |
| nif_obo_annot:definingCitation | Adams et al., Principles of Neurology, 6th ed, p1075-6 |
| nif_obo_annot:definingCitationURI | http://www.ninds.nih.gov/disorders/msa_orthostatic_hypotension/msa_orthostatic_hypotension.htm |
| nif_obo_annot:hasDefinitionSource | http://ontology.neuinfo.org/NIF/Backend/OBO_annotation_properties.owl#MeSH_defSource |
| nif_obo_annot:hasExternalSource | http://ontology.neuinfo.org/NIF/Backend/OBO_annotation_properties.owl#MeSH |
| nif_obo_annot:modifiedDate | 2007-10-05 |
| nif_obo_annot:synonym | Striatonigral Atrophy |
| Synonym | Striatonigral Atrophy |
| is_a | Multiple System Atrophy |
